Patents by Inventor Nobuo Kawahara

Nobuo Kawahara has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9668985
    Abstract: An object of the present invention is to provide a therapeutic preparation and method for diseases associated with cartilage loss, cartilage degeneration and/or cartilage thinning. The present invention provides a therapeutic preparation comprising a pterosin derivative or a pharmaceutically acceptable salt thereof for diseases associated with cartilage loss, cartilage degeneration and/or cartilage thinning; and a therapeutic method for the diseases.
    Type: Grant
    Filed: October 14, 2014
    Date of Patent: June 6, 2017
    Assignee: KYOTO UNIVERSITY
    Inventors: Noriyuki Tsumaki, Hiroshi Takemori, Hiroyuki Fuchino, Nobuo Kawahara
  • Publication number: 20150051293
    Abstract: An object of the present invention is to provide a therapeutic preparation and method for diseases associated with cartilage loss, cartilage degeneration and/or cartilage thinning. The present invention provides a therapeutic preparation comprising a pterosin derivative or a pharmaceutically acceptable salt thereof for diseases associated with cartilage loss, cartilage degeneration and/or cartilage thinning; and a therapeutic method for the diseases.
    Type: Application
    Filed: October 14, 2014
    Publication date: February 19, 2015
    Inventors: Noriyuki TSUMAKI, Hiroshi TAKEMORI, Hiroyuki FUCHINO, Nobuo KAWAHARA
  • Publication number: 20110196103
    Abstract: An olefin polymerization catalyst having (A) a transition metal compound (2a) or (3a) and (B) at least one compound selected from (B-1) an organometallic compound, (B-2) an organoaluminum oxy compound and (B-3) a compound capable of forming an ion pair by reacting with the transition metal compound (A).
    Type: Application
    Filed: April 22, 2011
    Publication date: August 11, 2011
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Nobuo Kawahara, Shinichi Kojoh, Norio Kashiwa
  • Patent number: 7868097
    Abstract: A hybrid polymer has a structure in which a polyolefin segment and a polar polymer segment are connected not via a bonding group containing a heteroatom. A method of the invention produces the hybrid polymer with industrial advantages. The hybrid polymer includes a polyolefin segment (A) and a polar polymer segment (B), the polar polymer segment being obtained by radical polymerization of a radically polymerizable monomer.
    Type: Grant
    Filed: February 21, 2006
    Date of Patent: January 11, 2011
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Hideyuki Kaneko, Shinichi Kojoh, Nobuo Kawahara, Shingo Matsuo, Tomoaki Matsugi, Norio Kashiwa
  • Patent number: 7847021
    Abstract: A modified polyolefin resin comprising a copolymer having a structure that a propylene-based polyolefin segment (a) and a segment (b) containing a lactic acid as a constituent are bonded in a block state and/or a graft state through a vinyl monomer having a hydroxyl group, wherein a number average molecular weight of the propylene-based polyolefin segment (a) is from 1,000 to 100,000, a number average molecular weight of the segment (b) containing lactic acid as a constituent is from 1,000 to 200,000, and a weight composition of the propylene-based polyolefin segment (a) and the segment (b) containing lactic acid as a constituent is from 10/90 to 90/10. The modified polyolefin resin can be used in a resin composition containing an aliphatic polyester resin (A), a polyolefin resin (B) and the modified polyolefin resin (C). The composition can exhibit excellent heat resistance and impact resistance and can be used for molding various parts.
    Type: Grant
    Filed: February 9, 2005
    Date of Patent: December 7, 2010
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Hosei Shinoda, Takeshi Kashima, Masahiro Enna, Shinichi Kojoh, Hideyuki Kaneko, Shingo Matsuo, Nobuo Kawahara, Tomoaki Matsugi, Yuichi Matsuda, Takayuki Onogi, Fumio Kageyama
  • Patent number: 7803888
    Abstract: A novel olefin-based polymer has excellent thermal resistance, as well as excellent balance among various properties. The olefin-based polymer is an olefin-based polymer comprising 50 to 100% by weight of a constituent unit derived from 4-methyl-1-pentene, and 0 to 50% by weight of a constituent unit derived from at least one olefin selected from olefins having 2 to 20 carbon atoms except 4-methyl-1-pentene, and having the following properties: i) the diad isotacticity is 70% or greater, ii) the ratio (Mw/Mn) of the weight average molecular weight (Mw) to the number average molecular weight (Mn) as measured by gel permeation chromatography (GPC) is in the range of 1.0 to 3.5, and iii) the intrinsic viscosity [?] is 0.5 (dl/g) or greater.
    Type: Grant
    Filed: June 9, 2005
    Date of Patent: September 28, 2010
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Nobuo Kawahara, Shinichi Kojoh, Shingo Matsuo, Hideyuki Kaneko, Tomoaki Matsugi, Norio Kashiwa, Munehito Funaya, Naritoshi Hirota, Tooru Tanaka, Toshiyuki Hirose, Nobuhisa Mikawa, Kouichi Kizu, Keiji Okada
  • Patent number: 7795347
    Abstract: A group of polymers comprising a plurality of polyolefin chains and polar polymer chains and having a multi-branched structure such as a block structure, a graft structure and a star-shaped structure is produced efficiently by polymerizing or reacting a combination of various polar monomers and their polymers i.e. polar polymer chains by using a functional group-containing polyolefin as a macroinitiator, a macromonomer or a reactive polymer. The resulting multi-branched polymer has a specific shape such as a block structure, a graft structure or a star-shaped structure, and has properties of both the polyolefin and polar polymer, thus exhibiting useful performance in various uses in films and compatibilizing agents as a novel polyolefin-based polymer.
    Type: Grant
    Filed: March 11, 2004
    Date of Patent: September 14, 2010
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Hideyuki Kaneko, Tomoaki Matsugi, Shin-Ichi Kojoh, Shingo Matsuo, Nobuo Kawahara, Norio Kashiwa
  • Patent number: 7767313
    Abstract: A polypropylene composite film having a propylene/1-butene random copolymer which has 60 to 90 mol % of propylene units and 10 to 40 mol % of 1-butene units and has a triad isotacticity of not less than 85% and not more than 97.5%, a molecular weight distribution of from 1 to 3, an intrinsic viscosity of from 0.1 to 12 dl/g, a melting point of from 40 to 75° C. and a crystallization rate at 45° C. of 10 minutes or less, and satisfying the following relation, 146 exp (?0.022M)?Tm?125 exp (?0.032M), and an olefin catalyst for preparation thereof.
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: August 3, 2010
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Shigenobu Ikenaga, Keiji Okada, Hiroshi Hoya, Norihide Inoue, Nobuo Kawahara
  • Patent number: 7678934
    Abstract: A transition metal compound represented by the following formula (2a):
    Type: Grant
    Filed: August 4, 2008
    Date of Patent: March 16, 2010
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Naritoshi Hirota, Hiromu Kaneyoshi, Munehito Funaya, Koji Kawai, Nobuo Kawahara
  • Patent number: 7619030
    Abstract: An automobile part comprising a polypropylene resin composition, the polypropylene resin composition comprising a propylene homopolymer (A1), an elastomer (B) and an inorganic filler (C) in specified proportions. The polypropylene homopolymer (A1) exhibits an MFR (230° C.) of 20 to 300 g/10 min, a ratio of position irregular units derived from 2,1-insertion or 1,3-insertion of propylene monomer relative to all propylene structural units, determined from a 13C-NMR spectrum, each of 0.05% or less, and an Mw/Mn, determined by GPC, of 1 to 3.
    Type: Grant
    Filed: April 26, 2006
    Date of Patent: November 17, 2009
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Koji Kawai, Masahiro Yamashita, Yasushi Tohi, Keita Itakura, Ikunori Sakai, Mikio Hashimoto, Takeshi Minoda, Masamichi Naito, Toru Takaoka, Nobuo Kawahara, Hiromu Kaneyoshi
  • Publication number: 20090186985
    Abstract: The present invention relates to olefinic compositions comprising a functionalized branched olefin copolymer containing functionalized sidechains derived from olefin and at least one chain end nucleophilic heteroatom containing functional group with at least one protic hydrogen, optionally with one or more copolymerizable monomers, the copolymer characterized by having A) a Tg<?10° C. as measured by DSC; B) a Ta>100° C.; C) an elongation at break of greater than or equal to 500 percent; D) a Tensile Strength of greater than or equal to 1,500 psi (10,300 kPa) at 25° C.; E) a TMA temperature>80° C., and F) an elastic recovery of greater than or equal to 50 percent.
    Type: Application
    Filed: January 21, 2005
    Publication date: July 23, 2009
    Inventors: Roger L. Kuhlman, Timothy T. Wenzel, Yunwa W. Cheung, Phillip D. Hustad, Edmund M. Carnahan, John R. Briggs, Brian A. Jazdzewski, Wenbin Liang, Roji Mori, Kouichi Kizu, Nobuo Kawahara, Shingo Matuso, Shinichi Kojoh, Norio Kashiwa
  • Publication number: 20090124760
    Abstract: It is an object to provide a new polyolefin hybrid polymer composed of a polyolefin segment and a polar polymer segment (Z) and a method for manufacturing the hybrid polymer by an industrially advantageous procedure. A polyolefin hybrid polymer composed of a polyolefin segment and a polar polymer segment (Z), wherein the polyolefin hybrid polymer is a modified compound of maleic polyolefin (A), is characterized by comprising a constitutional unit represented by the general formula (I): wherein Z represents a polar polymer segment obtained by polymerizing monomers of at least one kind selected from organic compounds having at least one carbon-carbon unsaturated bond, and F represents a group including an unsaturated bond.
    Type: Application
    Filed: July 11, 2006
    Publication date: May 14, 2009
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Hideyuki Kaneko, Shinichi Kojoh, Nobuo Kawahara, Shingo Matsuo, Tomoaki Matsugi, Norio Kashiwa
  • Publication number: 20090076233
    Abstract: A novel hybrid polymer has a structure in which a polyolefin segment and a polar polymer segment are connected not via a bonding group containing a heteroatom. A method of the invention produces the hybrid polymer with industrial advantages. The hybrid polymer includes a polyolefin segment (A) and a polar polymer segment (B), the polar polymer segment being obtained by radical polymerization of a radically polymerizable monomer.
    Type: Application
    Filed: February 21, 2006
    Publication date: March 19, 2009
    Applicant: MITSUI CHEMICALS, INC.
    Inventors: Hideyuki Kaneko, Shinichi Kojoh, Nobuo Kawahara, Shingo Matsuo, Tomoaki Matsugi, Norio Kashiwa
  • Publication number: 20090043050
    Abstract: A polypropylene composition containing a propylene/1-butene random copolymer which contains 60 to 90 mol % of propylene units and 10 to 40 mol % of 1-butene units and has a triad isotacticity of not less than 85% and not more than 97.5%, a molecular weight distribution of from 1 to 3, an intrinsic viscosity of from 0.1 to 12 dl/g, a melting point of from 40 to 75° C. and a crystallization rate at 45° C. of 10 minutes or less, and satisfying the following relation, 146 exp (?0.022M)?Tm?125 exp (?0.032M), and an olefin catalyst for preparation thereof.
    Type: Application
    Filed: August 4, 2008
    Publication date: February 12, 2009
    Inventors: Shigenobu Ikenaga, Keiji Okada, Hiroshi Hoya, Norihide Inoue, Naritoshi Hirota, Hiromu Kaneyoshi, Munehito Funaya, Koji Kawai, Nobuo Kawahara, Shinichi Kojoh, Norio Kashiwa, Ryoji Mori
  • Patent number: 7488789
    Abstract: A propylene/1-butene random copolymer containing 60 to 90 mol % of propylene units and 10 to 40 mol % of 1-butene units and has a triad isotacticity of not less than 85% and not more than 97.5%, a molecular weight distribution of from 1 to 3, an intrinsic viscosity of from 0.1 to 12 dl/g, a melting point of from 40 to 75° C. and a crystallization rate at 45° C. of 10 minutes or less, and satisfying the following relation, 146 exp (?0.022M)?Tm?125 exp (?0.032M), and an olefin catalyst for preparation thereof.
    Type: Grant
    Filed: December 26, 2003
    Date of Patent: February 10, 2009
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Shigenobu Ikenaga, Keiji Okada, Hiroshi Hoya, Norihide Inoue, Naritoshi Hirota, Hiromu Kaneyoshi, Munehito Funaya, Koji Kawai, Nobuo Kawahara, Shinichi Kojoh, Norio Kashiwa, Ryoji Mori
  • Publication number: 20080312461
    Abstract: A transition metal compound represented by the following formula (2a):
    Type: Application
    Filed: August 4, 2008
    Publication date: December 18, 2008
    Inventors: Shigenobu Ikenaga, Keiji Okada, Hiroshi Takayasu, Norihide Inoue, Naritoshi Hirota, Hiromu Kaneyoshi, Munehito Funaya, Koji Kwawi, Nobuo Kawahara, Shinichi Kojoh, Norio Kashiwa, Ryoji Mori
  • Publication number: 20080306234
    Abstract: A propylene elastomer (PBER) comprising (a) 50 to 85 mol % of units derived from propylene, (b) 5 to 25 mol % of units derived from 1-butene and (c) 10 to 25 mol % of units derived from ethylene, and having a molar ratio of propylene content to ethylene content of from 89/11 to 70/30, and a modulus in tension (YM), as measured in accordance with JIS 6301, of not more than 40 Mpa.
    Type: Application
    Filed: August 4, 2008
    Publication date: December 11, 2008
    Inventors: Shigenobu Ikenaga, Keiji Okada, Hiroshi Takayasu, Norihide Inoue, Naritoshi Hirota, Hiromu Kaneyoshi, Munehito Funaya, Koji Kawai, Nobuo Kawahara, Shinichi Kojoh, Norio Kashiwa, Ryoji Mori
  • Publication number: 20080306219
    Abstract: An olefin polymerization catalyst having (A) a transition metal compound (2a) or (3a) and (B) at least one compound selected from (B-1) an organometallic compound, (B-2) an organoaluminum oxy compound and (B-3) a compound capable of forming an ion pair by reacting with the transition metal compound (A).
    Type: Application
    Filed: August 4, 2008
    Publication date: December 11, 2008
    Inventors: Shigenobu IKENAGA, Keiji OKADA, Hiroshi TAKAYASU, Norihide INOUE, Naritoshi HIROTA, Hiromu KANEYOSHI, Munehito FUNAYA, Koji KAWAI, Nobuo KAWAHARA, Shinichi KOJOH, Norio KASHIWA, Ryoji MORI
  • Publication number: 20080292896
    Abstract: A polypropylene composite film having a propylene/1-butene random copolymer which has 60 to 90 mol % of propylene units and 10 to 40 mol % of 1-butene units and has a triad isotacticity of not less than 85% and not more than 97.5%, a molecular weight distribution of from 1 to 3, an intrinsic viscosity of from 0.1 to 12 dl/g, a melting point of from 40 to 75° C. and a crystallization rate at 45° C. of 10 minutes or less, and satisfying the following relation, 146 exp (?0.022M)?Tm ?125 exp (?0.032M), and an olefin catalyst for preparation thereof.
    Type: Application
    Filed: August 4, 2008
    Publication date: November 27, 2008
    Inventors: Shigenobu Ikenaga, Keiji Okada, Hiroshi Takayasu, Norihide Inoue, Naritoshi Hirota, Hiromu Kaneyoshi, Munehito Funaya, Koji Kawai, Nobuo Kawahara, Shinichi Kojoh, Norio Kashiwa, Ryoji Mori
  • Patent number: 7449533
    Abstract: The metallocene compound according to the invention and the olefin polymerization catalyst containing the compound are intended to produce a catalyst capable of preparing an isotactic polymer with a high polymerization activity. The metallocene compound contains a substituted cyclopentadienyl group and a (substituted) fluorenyl group and has a structure wherein these groups are bridged by a hydrocarbon group or the like. The process for preparing a metallocene compound according to the invention is intended to selectively prepare a specific metallocene compound so as not to produce an isomer, and in this process an intermediate product is synthesized by a specific method.
    Type: Grant
    Filed: February 10, 2005
    Date of Patent: November 11, 2008
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Koji Kawai, Masahiro Yamashita, Yasushi Tohi, Nobuo Kawahara, Kenji Michiue, Hiromu Kaneyoshi, Ryoji Mori