Abstract: An object of the present invention is to provide a novel antischistosomal agent, and more specifically, to provide a novel drug capable of inhibiting a growth of schistosomes in vivo to prevent development of liver dysfunction due to eggs of the schistosomes in the case of infection with the schistosomes. The novel antischistosomal agent includes as an active ingredient a peroxide derivative. Specifically, the novel antischistosomal agent includes as an active ingredient a peroxide derivative represented by the general formula (I): where C represents an alicyclic hydrocarbon ring group which may be substituted, and n represents an integer of 1 to 6.

Abstract: An object of the present invention is to provide a novel antischistosomal agent, and more specifically, to provide a novel drug capable of inhibiting a growth of schistosomes in vivo to prevent development of liver dysfunction due to eggs of the schistosomes in the case of infection with the schistosomes. The novel antischistosomal agent includes as an active ingredient a peroxide derivative. Specifically, the novel antischistosomal agent includes as an active ingredient a peroxide derivative represented by the general formula (I): where C represents an alicyclic hydrocarbon ring group which may be substituted, and n represents an integer of 1 to 6.

Abstract: An object of the present invention is to provide a novel antischistosomal agent, and more specifically, to provide a novel drug capable of inhibiting a growth of schistosomes in vivo to prevent development of liver dysfunction due to eggs of the schistosomes in the case of infection with the schistosomes. The novel antischistosomal agent includes as an active ingredient a peroxide derivative. Specifically, the novel antischistosomal agent includes as an active ingredient a peroxide derivative represented by the general formula (I): where C represents an alicyclic hydrocarbon ring group which may be substituted, and n represents an integer of 1 to 6.

Abstract: A flow-metering valve for metering a flow of liquid has a valve member, a stopper and an electromagnetic driving member. The valve member is reciprocally displaceably arranged between a first position and a second position in the liquid chamber. The stopper is arranged at the second position in the liquid chamber. The electromagnetic driving member generates a magnetic attractive force between the valve member and the stopper to hold the valve member at the second position when the electromagnetic driving member is energized.

Abstract: A high pressure pump has a fuel passage and a pump chamber. Fuel flows into the pump chamber through the fuel passage. The high pressure pump includes a valve member and a plunger. The valve member is movable along a movable axis in a substantially axial direction of the valve member for controlling an amount of fuel flowing into the pump chamber through the fuel passage. The plunger is movable substantially along a movable axis in a substantially axial direction of the plunger. The plunger is capable of pressurizing fuel in the pump chamber to discharge fuel in the pump chamber. The movable axis of the valve member is displaced from the movable axis of the plunger substantially in parallel with each other.

Abstract: A fuel injection valve includes a substantially cylindrical housing that at least partially surrounds an outer periphery of a coil. The housing is formed of a magnetic material. A fixed core and a movable core are located on a radially inner side of the coil. The movable core is opposed to the fixed core. The movable core is attracted to the fixed core by magnetic attractive force generated between the movable core and the fixed core. A valve is axially movable together with the movable core. A holder is formed of a magnetic material separately from the housing. The holder connects with a first axial end of the housing. The holder accommodates the valve. A cap is formed of a magnetic material separately from both the housing and the holder. The cap connects with a second axial end of the housing.

Abstract: Multiple injection holes are formed in an injection hole plate. Each injection hole penetrates the injection hole plate. The injection hole is formed with an inlet side opening and an outlet side opening. The outlet side opening is formed in the shape of a flattened rectangle having a major axis and a minor axis. Therefore, the fuel flowing into the injection hole through the inlet side opening is injected in the shape of a film from the outlet side opening. Thus, liquid film splitting is promoted, so atomization of the fuel is promoted. Since the multiple injection holes are formed in the injection hole plate, the shape of a great fuel spray, which is formed by combining fuel sprays injected from the respective injection holes, can be adjusted easily.

Abstract: A flow-metering valve for metering a flow of liquid has a valve member, a stopper and an electromagnetic driving member. The valve m ember is reciprocally displaceably arranged between a first position and a second position in the liquid chamber. The stopper is arranged at the second position in the liquid chamber. The electromagnetic driving member generates a magnetic attractive force between the valve member and the stopper to hold the valve member at the second position when the electromagnetic driving member is energized.

Abstract: In an injection hole plate of a fuel injection apparatus, a second-side hole section of each injection hole extends from a downstream end of a base wall of the injection hole plate and is communicated with first-side hole sections, which extends from an upstream end of the wall of the injection hole plate to an axially intermediate point of the wall. The first-side hole sections may discharge fuel into the second-side hole section in a manner that forms a swirl fuel flow in the second-side hole section. The injection hole plate may includes a collision portion, in which fuel flows supplied from the first-side hole sections collide with one another.

Abstract: A high pressure pump has a fuel passage and a pump chamber. Fuel flows into the pump chamber through the fuel passage. The high pressure pump includes a valve member and a plunger. The valve member is movable along a movable axis in a substantially axial direction of the valve member for controlling an amount of fuel flowing into the pump chamber through the fuel passage. The plunger is movable substantially along a movable axis in a substantially axial direction of the plunger. The plunger is capable of pressurizing fuel in the pump chamber to discharge fuel in the pump chamber. The movable axis of the valve member is displaced from the movable axis of the plunger substantially in parallel with each other.

Abstract: A fuel injection valve includes a valve body, a nozzle plate, and a weld portion. The valve body includes an axial end portion that has an opening and an inner periphery connecting with each other. The inner periphery is a substantially conical surface defining a valve seat. The nozzle plate is provided to the axial end portion of the valve body. The valve body and the nozzle plate define a boundary portion therebetween. The nozzle plate has a plurality of nozzle holes, through which an end surface of the nozzle plate on a side of the opening of the valve body communicates with an end surface of the nozzle plate on a side opposite to the valve body. The weld portion connects the valve body with the nozzle plate. The weld portion extends from an outer circumferential periphery of the boundary portion to an inner side in a radial direction of the valve body.

Abstract: A nozzle holder includes a support portion, which supports a downstream end surface of a planar wall of an injection hole plate. The injection hole plate provided with injection holes is welded to one of the valve body and the nozzle holder. The planar wall may be curved and may be thus convex in an upstream direction toward a downstream end opening such that the planar wall is urged against a peripheral edge of the downstream end opening of the valve body. The planar wall may include a reinforcing rib located radially outward of the injection hole.

Abstract: Multiple injection holes are formed in an injection hole plate. Each injection hole penetrates the injection hole plate. The injection hole is formed with an inlet side opening and an outlet side opening. The outlet side opening is formed in the shape of a flattened rectangle having a major axis and a minor axis. Therefore, the fuel flowing into the injection hole through the inlet side opening is injected in the shape of a film from the outlet side opening. Thus, liquid film splitting is promoted, so atomization of the fuel is promoted. Since the multiple injection holes are formed in the injection hole plate, the shape of a great fuel spray, which is formed by combining fuel sprays injected from the respective injection holes, can be adjusted easily.

Abstract: In an injection hole plate of a fuel injection apparatus, a second-side hole section of each injection hole extends from a downstream end of a base wall of the injection hole plate and is communicated with first-side hole sections, which extends from an upstream end of the wall of the injection hole plate to an axially intermediate point of the wall. The first-side hole sections may discharge fuel into the second-side hole section in a manner that forms a swirl fuel flow in the second-side hole section. The injection hole plate may includes a collision portion, in which fuel flows supplied from the first-side hole sections collide with one another.

Abstract: A nozzle holder includes a support portion, which supports a downstream end surface of a planar wall of an injection hole plate. The injection hole plate provided with injection holes is welded to one of the valve body and the nozzle holder. The planar wall may be curved and may be thus convex in an upstream direction toward a downstream end opening such that the planar wall is urged against a peripheral edge of the downstream end opening of the valve body. The planar wall may include a reinforcing rib located radially outward of the injection hole.

Abstract: An electromagnetic fuel injection valve prevents fuel bubbles from staying at a downstream side of the valve's stopper plate and helps to inject fuel smoothly. The electromagnetic injection valve includes a needle having a valve head opening and closing a valve seat, an electromagnetic coil portion for actuating the needle electromagnetically and a contact portion disposed at the downstream side of the stopper plate on the needle. The stopper plate includes a notch accommodating the needle therein and bubble discharge surfaces made outwardly from the notch to discharge bubbles produced at the downstream side of the contact portion toward the upstream side thereof and help the fuel flow smoothly.

Abstract: An electromagnetically operated valve for injecting fluid comprises first guiding element connected to one end portion of a stationary iron core and containing a movable core slidably therein for guiding a movement of a movable valve connected to the movable core, and second guiding element for slidably guiding the movable valve in a position between a large-diameter portion and a seat portion of the movable valve. According to such fluid injection valve, as the movable core and movable valve are axially guided by first guiding means and second guiding element in the above respective positions, the wear of the stopper portion of the movable valve is lessened due to the outer force to the movable valve.