Patents by Inventor Nobuo Sugiura

Nobuo Sugiura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4517180
    Abstract: This invention provides a peptide represented by the formulaR--Tyr(SO.sub.3 H)--Met--Gly--Trp--Met--Asp--W--NH.sub.2wherein R is HOOC--A--CO--Asp-- (wherein A is lower alkylene), pGlu--Asp--, HOOC--A--CO-- (wherein A is lower alkylene) or ##STR1## and W is Phe or N.sup..alpha. -lower alkyl-Phe, or a salt thereof, process for preparing the peptide and psychodepressant composition containing the peptide.The peptides of the invention are useful as psychodepressant drug, and especially effective for curing schizophrenia.
    Type: Grant
    Filed: October 27, 1983
    Date of Patent: May 14, 1985
    Assignees: Amano Pharmaceutical Co., Ltd, Otsuka Pharmaceutical Co., Ltd.
    Inventors: Noboru Yanaihara, Nobuo Sugiura, Takashi Hiyama
  • Patent number: 4330466
    Abstract: A novel process for the production of cholecystokininpancreozymin C-terminal peptide amide sulfate esters in a high yield and through a simple operation is described. A protected peptide amide is reacted with sulfur trioxide-pyridine complex and resulting protected piptide amide sulfate ester is then isolated in the form of its calcium salt. Thereafter, the protecting groups and calcium are removed. Sulfuric acid resulting from unreacted sulfur trioxide-pyridine complex may be precipitated and easily removed in the form of calcium sulfate.
    Type: Grant
    Filed: December 16, 1980
    Date of Patent: May 18, 1982
    Assignee: Amano Pharmaceutical Co., Ltd.
    Inventors: Noboru Yanaihara, Nobuo Sugiura