Patents by Inventor Nobuyuki Miyajima

Nobuyuki Miyajima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8138123
    Abstract: The present invention provides a tool for analysis of expression of Macaca fascicularis gene expression analysis tool containing a set of nucleic acids containing base sequences the same or substantially the same as two or more base sequences selected from the group consisting of the base sequences shown by SEQ ID NOs:1-14, or partial sequences thereof, and a method of analyzing the expression of Macaca fascicularis gene, including measuring a gene transcription product in a Macaca fascicularis sample using the tool.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: March 20, 2012
    Assignees: Takeda Pharmaceutical Company Limited, Shin Nippon Biomedical Laboratories, Ltd.
    Inventors: Nobuyuki Miyajima, Akira Horinouchi, Kenji Takami, Ryota Ise
  • Publication number: 20090048116
    Abstract: The present invention provides a tool for analysis of expression of Macaca fascicularis gene. The present invention provides a Macaca fascicularis gene expression analysis tool containing a set of nucleic acids containing base sequences the same or substantially the same as two or more base sequences selected from the group consisting of the base sequences shown by SEQ ID NOs: 1-14, or partial sequences thereof, and a method of analyzing the expression of Macaca fascicularis gene, including measuring a gene transcription product in a Macaca fascicularis sample using the tool.
    Type: Application
    Filed: January 26, 2007
    Publication date: February 19, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Nobuyuki Miyajima, Akira Horinouchi, Kenji Takami, Ryota Ise
  • Patent number: 7250272
    Abstract: The present invention aims at providing a useful and novel G protein-coupled receptor protein and DNA thereof. The G protein-coupled receptor protein of the present invention and the like, and the polynucleotides encoding the receptor protein and the like, are useful for; 1) determination of ligands (agonists); 2) preparation of antibodies and antisera; 3) construction of recombinant receptor protein expression systems; 4) development of the receptor binding assay systems using the expression systems and screening of pharmaceutical candidate compounds; 5) effecting drug design based on comparison with structurally similar ligand receptors; 6) reagents for preparation of probes and PCR primers for gene diagnosis; 7) production of transgenic animals; and 8) pharmaceutical drugs for the gene prophylaxis and gene therapy.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: July 31, 2007
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Syuji Sato, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20060057663
    Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.
    Type: Application
    Filed: July 6, 2001
    Publication date: March 16, 2006
    Inventors: Masanori Miwa, Takashi Ito, Natsuki Ikeda, Yasuko Terao, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040248321
    Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.
    Type: Application
    Filed: May 19, 2003
    Publication date: December 9, 2004
    Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040146967
    Abstract: The present invention provides a novel G protein-coupled receptor comprising the same or substantially the same amino acid sequence as that represented by SEQ ID NO: 1, or a salt thereof, and a polynucleotide encoding the same. The present invention also provides their use such as pharmaceuticals, etc.
    Type: Application
    Filed: January 13, 2003
    Publication date: July 29, 2004
    Inventors: Keiji Iwamoto, Nobuyuki Miyajima, Yasushi Shintani
  • Publication number: 20040110920
    Abstract: The present invention aims at providing a useful and novel G protein-coupled receptor protein and DNA thereof.
    Type: Application
    Filed: April 9, 2003
    Publication date: June 10, 2004
    Inventors: Syuji Sato, Yasushi Shintani, Nobuyuki Miyajima, Koji Yoshimura
  • Publication number: 20040101875
    Abstract: The present invention provides a novel G protein-coupled receptor comprising the same or substantially the same amino acid sequence as that represented by SEQ ID NO: 1, or a salt thereof, and a polynucleotide encoding the same. The present invention also provides their use such as pharmaceuticals, etc.
    Type: Application
    Filed: April 25, 2003
    Publication date: May 27, 2004
    Inventors: Keiji Iwamoto, Nobuyuki Miyajima, Yasushi Shintani
  • Publication number: 20040086505
    Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.
    Type: Application
    Filed: January 6, 2003
    Publication date: May 6, 2004
    Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040086940
    Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.
    Type: Application
    Filed: January 3, 2003
    Publication date: May 6, 2004
    Inventors: Sachio Shibata, Kenichi Horikoshi, Yoshio Taniyama, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040072751
    Abstract: The present invention aims at providing a useful and novel G protein-coupled receptor protein and DNA thereof.
    Type: Application
    Filed: April 1, 2003
    Publication date: April 15, 2004
    Inventors: Masanori Miwa, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040067553
    Abstract: The present invention intends to screen a novel G protein-coupled receptor protein and to elucidate its function.
    Type: Application
    Filed: June 23, 2003
    Publication date: April 8, 2004
    Inventors: Masanori Miwa, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040048284
    Abstract: The present invention intends to provide a novel protein useful for a screening of agonist/antagonist, and the like. Specifically, the present invention provides a novel protein or its salt, a DNA encoding the protein, a determination method of ligand for the protein, a screening method/kit for a compound that alters a binding property between a ligand and the protein, a compound obtained from the screening or its salt, and the like.
    Type: Application
    Filed: June 4, 2003
    Publication date: March 11, 2004
    Inventors: Shuji Sato, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040038238
    Abstract: The present invention provides a human-derived protein or a salt thereof, a DNA encoding the same, a method for determination of ligand to the protein, a screening method/kits for a compound or its salt that alters a binding property between ligand and the protein, and the like. The human-derived protein or a DNA encoding the same of the present invention can be used in (1) determination of ligand to the protein of the present invention, (2) a prophylactic/therapeutic agent for diseases associated with dysfunction of the protein of the present invention, (3) a screening of a compound (agonist, antagonist, etc.) that alters a binding property between the protein and the ligand of the present invention, and the like.
    Type: Application
    Filed: January 6, 2003
    Publication date: February 26, 2004
    Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20040029793
    Abstract: The present invention provides a novel G protein-coupled receptor protein comprising the same or substantially the same amino acid sequence as that represented by SEQ ID NO: 5 or salts thereof, and a polynucleotide encoding the same. The present invention also provides a use such as pharmaceuticals, etc.
    Type: Application
    Filed: May 1, 2003
    Publication date: February 12, 2004
    Inventors: Takeo Moriya, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20030162252
    Abstract: The present invention provides a novel G protein-coupled receptor protein comprising the same or substantially the same amino acid sequence as that represented by SEQ ID NO: 1 or salts thereof, and a polynucleotide encoding the same. The present invention also provides a use such as pharmaceuticals, etc.
    Type: Application
    Filed: December 20, 2002
    Publication date: August 28, 2003
    Inventors: Masanori Miwa, Takashi Ito, Yasushi Shintani, Nobuyuki Miyajima
  • Publication number: 20030157648
    Abstract: The present invention aims at screening of a novel G protein-coupled receptor protein and elucidation of its function.
    Type: Application
    Filed: March 11, 2003
    Publication date: August 21, 2003
    Inventors: Takeo Moriya, Takashi Ito, Ysushi Shintani, Nobuyuki Miyajima
  • Patent number: 5286693
    Abstract: A method of producing a catalyst for converting hydrocarbons involves spray-drying a slurry containing crystalline aluminosilicate zeolite and magnesium silicate mineral. The magnesium silicate mineral functioning as a metal trap contains 10 to 60 wt % of magnesium as an oxide. The magnesium silicate mineral has been treated with a phosphorus-containing solution.
    Type: Grant
    Filed: November 4, 1992
    Date of Patent: February 15, 1994
    Assignee: Nippon Oil Co., Ltd.
    Inventors: Takashi Ino, Kazumasa Hamatani, Nobuyuki Miyajima, Kazuya Nasuno
  • Patent number: 5094840
    Abstract: A novel foaming agent in dentifrice compositions, e.g., tooth pastes, is proposed which is an at least partially, with a basic compound, neutralized salt of a glycerin diester compound represented by the general formulaR.sup.1 --CO--O--CH.sub.2 --CHOH--CH.sub.2 --O--CO--R.sup.2,in which R.sup. 1 --CO--is a residue of a monobasic carboxylic acid having 8 to 18 carbon atoms in a molecule, e.g., lauric acid, and R.sup.2 is a residue of a polybasic carboxylic acid, e.g., succinic acid, from which one of the carboxyl groups is eliminated of which is a 1% by weight aqueous solution has a pH value in the range from 4 to 10 at 25.degree. C. The dentifrice composition compounded with 0.1-10% by weight of the above defined foaming agent has outstandingly high foamability and is advantageous in respect of the little adverse influences on the stability of enzymes contained in the dentrifrices composition.
    Type: Grant
    Filed: October 23, 1990
    Date of Patent: March 10, 1992
    Assignee: Lion Corporation
    Inventors: Kenji Isobe, Nobuyuki Miyajima, Hiroshi Yutani
  • Patent number: 4738790
    Abstract: This invention provides a detergent composition by which proteinaceous depositions can be easily removed from contact lenses in a short time, and a method for removing such depositions from the contact lenses. The detergent composition comprises an anionic or amidoamine-type ampholytic surfactant; and thiourea or a reductant.
    Type: Grant
    Filed: August 5, 1985
    Date of Patent: April 19, 1988
    Assignee: Toyo Contact Lens Co., Ltd.
    Inventors: Nobuyuki Miyajima, Kenji Hata, Junichi Nakayama