Patents by Inventor Nobuyuki Susumu

Nobuyuki Susumu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220033911
    Abstract: Provided are a method for determining prognosis of endometrial cancer, a method for determining endometrial cancer patient compatible to preservation therapy, and a method for determining risk of endometrial cancer. The methods comprise detecting DNA methylation level at a target CpG site in a genomic DNA derived from an endometrial cell, endometrial cancer cell or tissue containing the cell. Prognosis of endometrial cancer, compatibility to preservation therapy, or risk of endometrial cancer of a subject is determined on the basis of the detected DNA methylation level.
    Type: Application
    Filed: December 5, 2019
    Publication date: February 3, 2022
    Applicants: KEIO UNIVERSITY, SEKISUI MEDICAL CO., LTD.
    Inventors: Yae KANAI, Eri ARAI, Daisuke AOKI, Nobuyuki SUSUMU, Wataru YAMAGAMI, Takeshi MAKABE
  • Patent number: 8518651
    Abstract: It is provided a method for identification of the morbidity of epithelial ovarian cancer based on a tissue-type in view of molecular typing which is different from a conventional histopathology, and a marker for identification of a tissue-type of epithelial ovarian cancer. A method for identification of the morbidity of epithelial ovarian cancer based on a tissue-type, comprising: subjecting a sample originated from an individual of interest to a treatment for detecting at least one selected from the group consisting of biological molecules specifically showing an upregulation in expression in a specific tissue-type of epithelial ovarian cancer, and/or at least one selected from the group consisting of biological molecules specifically showing a downregulation in expression in a specific tissue-type of epithelial ovarian cancer, and identifying whether or not the significant detection of the protein is achieved, thereby identifying the tissue-type.
    Type: Grant
    Filed: February 15, 2008
    Date of Patent: August 27, 2013
    Assignees: Shimadzu Corporation, Keio University
    Inventors: Taka-aki Sato, Atsuhiko Toyama, Takashi Shimada, Tetsuyoshi Sugita, Daisuke Aoki, Atsushi Suzuki, Nobuyuki Susumu, Hiroyuki Nomura
  • Publication number: 20100075354
    Abstract: It is provided a method for identification of the morbidity of epithelial ovarian cancer based on a tissue-type in view of molecular typing which is different from a conventional histopathology, and a marker for identification of a tissue-type of epithelial ovarian cancer. A method for identification of the morbidity of epithelial ovarian cancer based on a tissue-type, comprising: subjecting a sample originated from an individual of interest to a treatment for detecting at least one selected from the group consisting of biological molecules specifically showing an upregulation in expression in a specific tissue-type of epithelial ovarian cancer, and/or at least one selected from the group consisting of biological molecules specifically showing a downregulation in expression in a specific tissue-type of epithelial ovarian cancer, and identifying whether or not the significant detection of the protein is achieved, thereby identifying the tissue-type.
    Type: Application
    Filed: February 15, 2008
    Publication date: March 25, 2010
    Inventors: Taka-aki Sato, Atsuhiko Toyama, Takashi Shimada, Tetsuyoshi Sugita, Daisuke Aoki, Atsushi Suzuki, Nobuyuki Susumu, Hiroyuki Nomura
  • Publication number: 20090246769
    Abstract: A molecular diagnosis system of ovarian cancers encompasses a detection device configured to obtain a detected value of an expression amount of an apolipoprotein A1 gene in ovarian tissue as a diagnosis subject, a storage device configured to store a normal value of the expression amount of the apolipoprotein A1 gene in normal ovarian tissue, and a determination mechanism configured to determine that the ovarian tissue as the diagnosis subject is clear cell adenocarcinoma when the detected value is lower than the normal value.
    Type: Application
    Filed: October 6, 2008
    Publication date: October 1, 2009
    Applicants: SHIMADZU CORPORATION, KEIO UNIVERSITY
    Inventors: Takaaki SATO, Tetsuyoshi Sugita, Atsuhiko Toyama, Takashi Shimada, Daisuke Aoki, Atsushi Suzuki, Nobuyuki Susumu, Hiroyuki Nomura