Patents by Inventor Nobuyuki Yamagata

Nobuyuki Yamagata has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and therapeutic agent for autoimmune diseases containing the same
    Patent number: 6034064
    Abstract: The present invention relates to a peptide having the following amino acid sequence:Ala-Xaa1-Leu-Xaa2-Phe-Xaa3-Xaa4-Xaa5-(Xaa6)n(wherein Xaa1 and Xaa4 each independently represents an amino acid residue which may have an alkyl or heteroalkyl side chain which may be substituted by a hydroxy, amino or guanidyl group;Xaa2 and Xaa6 each independently represents an amino acid residue which may have an alkyl or heteroalkyl side chain which may be substituted by a hydroxyl group;Xaa3 and Xaa5 each independently represents an amino acid residue which may have a hydrophobic side chain; andn stands for 1 or 0), or derivatives thereof; and a modification thereof.The peptide or derivatives thereof according to the present invention is useful as a pharmaceutical composition for the prevention and treatment of autoimmune diseases, rejection reaction attendant on the organ transplantation, inflammation or the like.
    Type: Grant
    Filed: January 8, 1998
    Date of Patent: March 7, 2000
    Assignee: Hoechst Pharmaceuticals & Chemicals K.K.
    Inventors: Nobuyuki Yamagata, Kenji Ogata, Masako Wagatsuma, Hitoshi Takanashi
  • Method of treating diabetes mellitus using variable .alpha. domain of T-cell receptor
    Patent number: 5648332
    Abstract: A soluble T-cell receptor .alpha.-chain produced by suppressor T-cell. The said soluble T-cell receptor .alpha.-chain is useful as a prophylactic and therapeutic agent for autoimmune diseases generated to a wide variety of autoantigens irrespective of specificity to the said suppressor T-cell.
    Type: Grant
    Filed: October 20, 1994
    Date of Patent: July 15, 1997
    Assignee: Hoechst Japan Limited
    Inventors: Hiroshi Watanabe, Nobuyuki Yamagata, Masaru Taniguchi