Abstract: An apparatus (7) for localised application of a substance to a site within the oral cavity has a reservoir (9) for receipt of the substance to be applied, and a mounting arrangement (11) a for mounting the apparatus within the oral cavity. The mounting arrangement (11) is configured to place the reservoir (9) in contact with the site to which the substance is to be applied to substantially form a seal between the reservoir and the site to which the substance is to be applied.

Abstract: Apparatus for harvesting material from micro-culture plates comprises either a harvester plate or, in combination a harvester plate and a micro-culture plate, the harvester plate having a plurality of wells recessed into one surface thereof, these wells conforming in size, number and arrangement to the wells of the micro-culture plate, and the wells of the harvester plate being adapted to hold filter elements for absorbing liquid from corresponding wells of the culture plate when the wells of the culture plate, with the culture plate in an upside-down orientation, are contacted with corresponding wells of the harvester plate, and in which the harvester plate wells have fluid outlets at their bases. Also a new micro-culture plate comprises a plurality of wells recessed into a surface thereof each well comprising a fluid inlet passageway through the base thereof.