Patents by Inventor Noel Aaron Powell

Noel Aaron Powell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ERGOLINE-LIKE COMPOUNDS FOR PROMOTING NEURAL PLASTICITY
    Publication number: 20230295106
    Abstract: Provided herein are ergoline-derived heterocyclic compounds which can be useful for methods of treating a disease or for increasing neural plasticity. The compounds can also be useful for increasing dendritic spine density.
    Type: Application
    Filed: October 14, 2020
    Publication date: September 21, 2023
    Inventors: David E. Olson, Lee Dunlap, Florence Wagner, Milan Chytil, Noel Aaron Powell
  • TRICYCLIC PSYCHOPLASTOGENS AND USES THEREOF
    Publication number: 20230227453
    Abstract: Disclosed herein are compounds, compositions, and methods for promoting neuronal growth and/or improving neuronal structure with the compounds and compositions disclosed herein. Also described are methods of treating diseases or disorders that are mediated by the loss of synaptic connectivity and/or plasticity, such as neurological diseases and disorders, with non-hallucinogenic psychoplastogens.
    Type: Application
    Filed: June 9, 2021
    Publication date: July 20, 2023
    Inventors: Florence WAGNER, Milan CHYTIL, Noel Aaron POWELL
  • ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF
    Publication number: 20230219969
    Abstract: Disclosed herein are compounds, compositions, and methods for promoting neuronal growth and/or improving neuronal structure with the compounds and compositions disclosed herein. Also described are methods of treating diseases or disorders that are mediated by the loss of synaptic connectivity and/or plasticity, such as neurological diseases and disorders, with non-hallucinogenic psychoplastogens.
    Type: Application
    Filed: June 9, 2021
    Publication date: July 13, 2023
    Inventors: Florence WAGNER, Noel Aaron POWELL, Milan CHYTIL, David E. OLSON
  • 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS
    Publication number: 20220185799
    Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
    Type: Application
    Filed: October 29, 2021
    Publication date: June 16, 2022
    Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Linghong XIE, Philip Glyn JONES, Kerry L. SPEAR, Noel Aaron POWELL, Taleen G. HANANIA, Vadim ALEXANDROV
  • 1-heterocyclyl isochromanyl compounds and analogs for treating CNS disorders
    Patent number: 11192885
    Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: December 7, 2021
    Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Linghong Xie, Philip Glyn Jones, Kerry L. Spear, Noel Aaron Powell, Taleen G. Hanania, Vadim Alexandrov
  • Compounds and compositions and uses thereof
    Patent number: 11077090
    Abstract: Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need thereof are also disclosed.
    Type: Grant
    Filed: July 28, 2017
    Date of Patent: August 3, 2021
    Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Vadim Alexandrov, Carrie A. Bowen, Taleen G. Hanania, Noel Aaron Powell
  • 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS
    Publication number: 20190389845
    Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
    Type: Application
    Filed: May 6, 2019
    Publication date: December 26, 2019
    Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Linghong Xie, Philip Glyn JONES, Kerry L. SPEAR, Noel Aaron POWELL, Taleen G. HANANIA, Vadim ALEXANDROV
  • 1-heterocyclyl isochromanyl compounds and analogs for treating CNS disorders
    Patent number: 10336732
    Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
    Type: Grant
    Filed: November 21, 2017
    Date of Patent: July 2, 2019
    Assignees: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Linghong Xie, Philip Glyn Jones, Kerry L. Spear, Noel Aaron Powell, Taleen G. Hanania, Vadim Alexandrov
  • 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS
    Publication number: 20180093974
    Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
    Type: Application
    Filed: November 21, 2017
    Publication date: April 5, 2018
    Applicants: Sunovion Pharmaceuticals Inc., PGI Drug Discovery LLC
    Inventors: Linghong Xie, Philip Glyn Jones, Kerry L. Spear, Noel Aaron Powell, Taleen G. Hanania, Vadim Alexandrov
  • COMPOUNDS AND COMPOSITIONS AND USES THEREOF
    Publication number: 20180028492
    Abstract: Compounds of formula I: are disclosed, as are pharmaceutical compositions containing such compounds. Methods of treating neurological or psychiatric diseases and disorders in a subject in need thereof are also disclosed.
    Type: Application
    Filed: July 28, 2017
    Publication date: February 1, 2018
    Inventors: Noel Aaron POWELL, Taleen G. HANANIA, Vadim ALEXANDROV, Carrie A. BOWEN
  • 1-heterocyclyl isochromanyl compounds and analogs for treating CNS disorders
    Patent number: 9856238
    Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: January 2, 2018
    Assignees: SUNOVION PHARMACEUTICALS INC., PGI DRUG DISCOVERY LLC
    Inventors: Linghong Xie, Philip Glyn Jones, Kerry L. Spear, Noel Aaron Powell, Taleen G. Hanania, Vadim Alexandrov
  • 1-HETEROCYCLYL ISOCHROMANYL COMPOUNDS AND ANALOGS FOR TREATING CNS DISORDERS
    Publication number: 20170001987
    Abstract: Disclosed are compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, Ra, R1, R2, R3, R4, R6, w and n1 are defined and described herein; compositions thereof; and methods of use thereof. These compounds are useful for treating a variety of neurological and psychiatric disorders, such as those described herein.
    Type: Application
    Filed: February 11, 2016
    Publication date: January 5, 2017
    Inventors: Linghong Xie, Philip Glyn Jones, Kerry L. Spear, Noel Aaron Powell, Taleen G. Hanania, Vadim Alexandrov
  • Piperazine derivative renin inhibitors
    Publication number: 20040214832
    Abstract: Disclosed are piperazine derivatives, their manufacture and use as inhibitors of renin.
    Type: Application
    Filed: March 26, 2004
    Publication date: October 28, 2004
    Inventors: Cuiman Cai, Emma Hazel Clay, Dennis M. Downing, Jeremy John Edmunds, Daniel Dale Holsworth, Tingsheng Li, Noel Aaron Powell
  • Piperidine derivative rennin inhibitors
    Publication number: 20040204455
    Abstract: Disclosed are piperidine derivatives, their manufacture and use as inhibitors of renin.
    Type: Application
    Filed: March 26, 2004
    Publication date: October 14, 2004
    Inventors: Wayne Livingston Cody, Jeremy John Edmunds, Daniel Dale Holsworth, Noel Aaron Powell