Patents by Inventor Noel Hillier SMITH

Noel Hillier SMITH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CRISPR-associated (Cas) proteins with reduced immunogenicity
    Patent number: 11566052
    Abstract: The invention relates to methods of reducing the immunogenicity of CRISPR-associated (Cas) proteins and the modified Cas proteins produced therefrom. In addition, the invention relates to methods for cell and gene therapy, including any and all genetic modifications and alterations of gene expression (and/or genetic elements) made in-vivo or ex-vivo using Cas proteins with reduced immunogenicity.
    Type: Grant
    Filed: November 11, 2016
    Date of Patent: January 31, 2023
    Assignee: LONZA LTD.
    Inventors: Thomas Payne, Jesús Zurdo, Noel Hillier Smith
  • CRISPR-ASSOCIATED (Cas) PROTEINS WITH REDUCED IMMUNOGENICITY
    Publication number: 20180319850
    Abstract: The invention relates to methods of reducing the immunogenicity of CRISPR-associated (Cas) proteins and the modified Cas proteins produced therefrom. In addition, the invention relates to methods for cell and gene therapy, including any and all genetic modifications and alterations of gene expression (and/or genetic elements) made in-vivo or ex-vivo using Cas proteins with reduced immunogenicity.
    Type: Application
    Filed: November 11, 2016
    Publication date: November 8, 2018
    Inventors: Thomas PAYNE, Jesús ZURDO, Noel Hillier SMITH