Abstract: Systems and methods are provided for locking equipment exposure settings. The system includes a safety interlock device coupled to an access point of a barrier and equipment enclosed thereby. The safety interlock device is configured to suspend a normal operation of the equipment while in an open state and allow the normal operation while in a closed state. The system includes an access point control device configured to allow a user to select among exposure settings for the equipment corresponding to operability of the equipment, and to, by a processor: control the equipment to operate in accordance with a selected exposure setting, determine whether the safety interlock device is in the open or closed state, automatically lock the selected exposure setting if the safety interlock device is in the open state, and automatically unlock the selected exposure setting if the safety interlock device is in the closed state.