Patents by Inventor Noel SAUER

Noel SAUER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20240084316
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: September 18, 2023
    Publication date: March 14, 2024
    Applicants: CIBUS US LLC, Cibus Europe B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20230407322
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Application
    Filed: January 2, 2023
    Publication date: December 21, 2023
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 11761011
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Grant
    Filed: March 22, 2021
    Date of Patent: September 19, 2023
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 11542515
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: January 3, 2023
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20210261974
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: March 22, 2021
    Publication date: August 26, 2021
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
    Patent number: 10954522
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Grant
    Filed: April 30, 2018
    Date of Patent: March 23, 2021
    Assignees: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20190249182
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Application
    Filed: September 16, 2016
    Publication date: August 15, 2019
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20180320190
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: April 30, 2018
    Publication date: November 8, 2018
    Applicants: CIBUS US LLC, CIBUS EUROPE B.V.
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • Methods and compositions for targeted gene modification
    Patent number: 9957515
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: May 1, 2018
    Assignees: CIBUS US LLC, CIBUS EUROPE, B.V.
    Inventors: Peter R. Beetham, Gregory F. W. Gocal, Christian Schopke, Noel Sauer, James Pearce, Rosa E. Segami, Jerry Mozoruk
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20170081674
    Abstract: Provided herein include methods and compositions for making targeted changes to a DNA sequence. In various aspects and embodiments, methods and compositions for modifying a DNA sequence in a cell (such as a plant, bacterial, yeast, fungal, algal, or mammalian cell) are provided. In some aspects and embodiments the modification of DNA involves combining gene repair oligonucleotides with approaches that enhance the availability of components of the target cell gene repair mechanisms, such as a DNA cutter.
    Type: Application
    Filed: March 14, 2015
    Publication date: March 23, 2017
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK
  • METHODS AND COMPOSITIONS FOR INCREASING EFFICIENCY OF TARGETED GENE MODIFICATION USING OLIGONUCLEOTIDE-MEDIATED GENE REPAIR
    Publication number: 20170051296
    Abstract: Provided herein include methods and compositions for effecting a targeted genetic change in DNA in a cell. Certain aspects and embodiments relate to improving the efficiency of the targeting of modifications to specific locations in genomic or other nucleotide sequences. As described herein, nucleic acids which direct specific changes to the genome may be combined with various approaches to enhance the availability of components of the natural repair systems present in the cells being targeted for modification.
    Type: Application
    Filed: March 14, 2016
    Publication date: February 23, 2017
    Inventors: Peter R. BEETHAM, Gregory F.W. GOCAL, Christian SCHOPKE, Noel SAUER, James PEARCE, Rosa E. SEGAMI, Jerry MOZORUK