Patents by Inventor Noemí VILA MOLARES

Noemí VILA MOLARES has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyridazin-3(2H)-one derivatives as monoamine oxidase selective isoform B inhibitors
    Patent number: 10253000
    Abstract: The present invention refers to pyridazin-3(2H)-one derivatives of general structure I, II and III, which are selective MAO-B inhibitors, and to the use thereof for preparing medicaments intended to treat disorders derived from MAO-B hyperactivity, particularly degenerative disorders of the central nervous system (CNS), such as Parkinson's disease (PD), Alzheimer's disease (AD) and other dementias. These are pyridazin-3(2H)-one derivatives having dithiocarbamate moieties bonded to position 4, 5 or 6 through an alkyl chain of variable length (n=1, 2, 3). This invention is also directed to the preparation of said compounds.
    Type: Grant
    Filed: March 3, 2015
    Date of Patent: April 9, 2019
    Assignees: UNIVERSIDADE DE VIGO, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
    Inventors: Ma del Carmen Terán Moldes, Pedro Besada Pereira, Tamara Costas Caamaño, Ma del Carmen Costas Lago, Noemí Vila Molares, Dolores Viña Castelao
  • PYRIDAZIN-3(2H)-ONE DERIVATIVES AS MONOAMINE OXIDASE SELECTIVE ISOFORM B INHIBITORS (As Amended)
    Publication number: 20180215718
    Abstract: The present invention refers to pyridazin-3(2H)-one derivatives of general structure I, II and III, which are selective MAO-B inhibitors, and to the use thereof for preparing medicaments intended to treat disorders derived from MAO-B hyperactivity, particularly degenerative disorders of the central nervous system (CNS), such as Parkinson's disease (PD), Alzheimer's disease (AD) and other dementias. These are pyridazin-3(2H)-one derivatives having dithiocarbamate moieties bonded to position 4, 5 or 6 through an alkyl chain of variable length (n=1, 2, 3). This invention is also directed to the preparation of said compounds.
    Type: Application
    Filed: March 3, 2015
    Publication date: August 2, 2018
    Applicants: UNIVERSIDADE DE VIGO, UNIVERSIDADE DE SANTIAGO DE COMPOSTELA
    Inventors: Mª del Carmen TERÁN MOLDES, Pedro BESADA PEREIRA, Tamara COSTAS CAAMAÑO, Mª del Carmen COSTAS LAGO, Noemí VILA MOLARES, Dolores VIÑA CASTELAO