Abstract: An apparatus for improving the procedure for quantifying the volume of liquid dispensed by a liquid-dispensing mechanism of an analytical instrument. The apparatus of this invention comprises (a) at least one weigh cup; (b) at least one standard mass; (c) at least one transducer assembly to convert a value of weight to an electrical response; and (d) at least one electronic circuit for converting the electrical response to a measurement of volume. This invention provides a method for calibrating readings of the volume of liquid dispensed by a liquid-dispensing mechanism of an analytical instruments so that absolute measurements of the volume of liquid dispensed can be obtained.

Abstract: A method for cleaning deposits of particulate material from the tip of a nozzle of a dispensing apparatus, such as, for example, the tip of the nozzle of a liquid reagent dispensing apparatus. The method involves the use of a multiple excitation signal waveform to cavitate and agitate the cleaning medium in which the tip of the nozzle is suspended. Multiple excitation refers to a method of excitation that uses waves of alternating polarity; multiple excitation may involve excitation at a plurality of frequencies in sequence, at a plurality of amplitudes in sequence, at a plurality of waveforms in sequence, combinations of the aforementioned frequencies, amplitudes, and waveforms. The invention also provides an apparatus incorporating electrical and mechanical components, along with appropriate software, sufficient to perform the method described herein.

Abstract: An apparatus for improving the procedure for quantifying the volume of liquid dispensed by a liquid-dispensing mechanism of an analytical instrument. The apparatus of this invention comprises (a) at least one weigh cup; (b) at least one standard mass; (c) at least one transducer assembly to convert a value of weight to an electrical response; and (d) at least one electronic circuit for converting the electrical response to a measurement of volume. This invention provides a method for calibrating readings of the volume of liquid dispensed by a liquid-dispensing mechanism of an analytical instruments so that absolute measurements of the volume of liquid dispensed can be obtained.