Patents by Inventor Norbert Bannert

Norbert Bannert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Processed polypeptides with IL-16 activity, process for preparing the same and their use
    Patent number: 6506582
    Abstract: A nucleic acid which can be used to express a polypeptide with interleukin-16 activity in a prokaryotic or eukaryotic host cell wherein the nucleic acid codes for a polypeptide with the amino acid sequence SEQ ID NO:2 or a SEQ ID NO:2 elongated N-terminally by an aspartic acid residue or a form shortened at the C-terminus by up to 8 amino acids, and is suitable for the production of an active IL-16 polypeptide.
    Type: Grant
    Filed: February 25, 1999
    Date of Patent: January 14, 2003
    Assignee: Bundesrepublik Deutschland vertreten durch den Bundesminister fur Gesundheit
    Inventors: Reinhard Kurth, Michael Baier, Norbert Bannert, Albrecht Werner, Kurt Lang
  • Genomic nucleic acids, cDNA and mRNA which code for polypeptides with IL-16 activity, processes for the production thereof and their use
    Patent number: 6338844
    Abstract: A nucleic acid with which expression of a polypeptide having interleukin-16 activity can be achieved or regulated in a prokaryotic or eukaryotic host cell, wherein in the region coding for the polypeptide, the nucleic acid (1) corresponds to the DNA sequence SEQ ID NOS:1 and 5-7 or its complementary strand; (b) hybridizes under stringent conditions with the DNA of sequence SEQ ID NOS:1 and 5-7; (c) or is a nucleic acid sequence which, if there was no degeneracy of the genetic code, would hybridize under stringent conditions with the nucleic acid sequences defined by (a) and (b); (d) and, if it codes for a polypeptide having interleukin-16 activity, is suitable as genomic DNA for the recombinant production of IL-16 in eukaryotic host cells and processes for producing the same and pharmaceutical compositions containing the same.
    Type: Grant
    Filed: May 11, 1999
    Date of Patent: January 15, 2002
    Assignee: Bundesrepublik Deutschland vertreten durch de Bundesminister für Gesundheit
    Inventors: Reinhard Kurth, Michael Baier, Norbert Bannert, Karin Metzner, Albrecht Werner
  • Polypeptides with interleukin-16 activity, process for the preparation and use thereof
    Patent number: 6207144
    Abstract: A nucleic acid which can be used to express a polypeptide with interleukin-16 activity in a prokaryotic or eukaryotic host cell, wherein in the region coding for the said polypeptide the said nucleic acid a)corresponds to the DNA sequence of nucleotides 54-1175 from SEQ ID NO:1 or to its complementary strand, b) hybridizes with the DNA of nucleotide sequence 54-785 from SEQ ID NO:1 under stringent conditions, c) hybridizes with the DNA of nucleotide sequence 786-1175 from SEQ ID NO:1 under stringent conditions and at the 5′ end begins with nucleotides 756-785 from SEQ ID NO:1 or a part thereof which codes for part of the sequence of amino acids 235-244 from SEQ ID NO:1 or d) it is a nucleic acid sequence which would hybridize under stringent conditions with the nucleic acid sequences defined by a) or b) without the degeneracy of the genetic code, codes for proteins with improved interleukin-16 activity.
    Type: Grant
    Filed: August 27, 1998
    Date of Patent: March 27, 2001
    Assignees: Roche Diagnostics, GmbH, Bundesrepublik Deutschland, vertreten durch den Bundesminister fur Gesundheit
    Inventors: Reinhard Kurth, Michael Baier, Norbert Bannert, Karin Metzner, Albrecht Werner, Kurt Lang