Patents by Inventor Norbert Gallus

Norbert Gallus has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 18-METHYL-6,7-METHYLENE-3-OXO-17-PREGN-4-ENE-21,17B-CARBOLACTONES, PHARMACEUTICAL PREPARATIONS COMPRISING SAID COMPOUNDS AND USE THEREOF IN THE TREATMENT OF ENDOMETRIOSIS
    Publication number: 20140288035
    Abstract: The present invention relates to 18-methyl-6,7-methylene-17-pregn-4-ene-21,17?-carbolactones of general formula I wherein the 6,7-methylene group can be in ?- or ? position, pharmaceutical preparations containing at least one isomer of formula I and use thereof in the treatment of endometriosis.
    Type: Application
    Filed: November 2, 2012
    Publication date: September 25, 2014
    Applicants: BAYER PHARMA AKTIENGESELLSCHAFT, BAYER INTELLECTUAL PROPERTY GMBH
    Inventors: Jan Hübner, Rolf Bohlmann, Isabella Gashaw, Oliver Martin Fischer, Joachim Kuhnke, Norbert Gallus, Reinhard Nubbemeyer, Ildiko Terebesi
  • 18-Methyl-19-norandrost-4-ene 17, 17-spiro ether (18-methyl-19-nor-20-spirox-4-en-3-one), and pharmaceutical products comprising the same
    Patent number: 7846917
    Abstract: The present invention describes the novel 18-methyl-19-norandrost-4-ene 17,17-spiro ethers of the general formula I in which Z is an oxygen atom, two hydrogen atoms, a group ?NOR or ?NNHSO2R, where R is a hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 or 3 to 4 carbon atoms, R4 is a hydrogen atom, a halogen atom or a trifluoromethyl group, and R6 and/or R7 may have ? or ? configuration, and R6 and R7 are independently of one another a hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 or 3 to 4 carbon atoms or a straight- or branched-chain alkenyl group having 2 to 4 or 3 to 4 carbon atoms or a saturated cycloalkyl group having 3 to 5 carbon atoms or together are a methylene group or a double bond. The novel compounds have progestational and antimineralocorticoid activity.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: December 7, 2010
    Assignee: Bayer Schering Pharma AG
    Inventors: Rolf Bohlmann, Joachim Kuhnke, Jan Huebner, Norbert Gallus, Frederik Menges, Steffen Borden, Hans-Peter Muhn, Katja Prelle
  • 18-Methyl-19-norandrost-4-ene 17, 17-spiro ether (18-methyl-19-nor-20-spirox-4-en-3-one), and pharmaceutical products comprising the same
    Publication number: 20080153787
    Abstract: The present invention describes the novel 18-methyl-19-norandrost-4-ene 17,17-spiro ethers of the general formula I in which Z is an oxygen atom, two hydrogen atoms, a group ?NOR or ?NNHSO2R, where R is a hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 or 3 to 4 carbon atoms, R4 is a hydrogen atom, a halogen atom or a trifluoromethyl group, and R6 and/or R7 may have a or a configuration, and R6 and R7 are independently of one another a hydrogen atom or a straight- or branched-chain alkyl group having 1 to 4 or 3 to 4 carbon atoms or a straight- or branched-chain alkenyl group having 2 to 4 or 3 to 4 carbon atoms or a saturated cycloalkyl group having 3 to 5 carbon atoms or together are a methylene group or a double bond. The novel compounds have progestational and antimineralocorticoid activity.
    Type: Application
    Filed: June 28, 2007
    Publication date: June 26, 2008
    Inventors: Rolf BOHLMANN, Joachim Kuhnke, Jan Huebner, Norbert Gallus, Frederik Menges, Steffen Borden, Hans-Peter Muhn, Katja Prelle
  • Microbiological process for the production of 7-substitued 11-hydroxy steroids, 7,17-substituted 11-halogen steroids, and uses thereof
    Publication number: 20070298456
    Abstract: A novel method of synthesis for the manufacture of upstream products for the production of compounds with general formulas 8, 10, and 12 is described. In this synthesis, compounds with general formula 4,B are produced in a microbiological reaction. The meanings of R7, R10, R11, R13, R17 and R17? as well as of the grouping U—V—W—X—Y-Z are indicated in the claims.
    Type: Application
    Filed: July 17, 2007
    Publication date: December 27, 2007
    Inventors: Lud-wig Zorn, Rolf Bohlmann, Norbert Gallus, Hermann Kuenzer, Hans-Peter Muhn, Reinhard Nubbemeyer
  • Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-Halogen steroids and uses thereof
    Patent number: 7262023
    Abstract: A novel method of synthesis for the manufacture of upstream products for the production of compounds with general formulas 8, 10, and 12 is described. In this synthesis, compounds with general formula 4,B are produced in a microbiological reaction.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: August 28, 2007
    Assignee: Bayer Schering Pharma AG
    Inventors: Ludwig Zorn, Rolf Bohlmann, Norbert Gallus, Hermann Kuenzer, Hans-Peter Muhn, Reinhard Nubbemeyer
  • Microbiological process for the production of 7-substituted 11-hydroxy steroids, 7,17-substituted 11-halogen steroids that can be produced therefrom, their process for production and use as well as pharmaceutical prepartions that contain these compounds, as well as 7-substituted estra-1,3,5(10)-trienses that can be produced therefrom
    Publication number: 20050090477
    Abstract: A novel method of synthesis for the manufacture of upstream products for the production of compounds with general formulas 8, 10, and 12 is described. In this synthesis, compounds with general formula 4,B are produced in a microbiological reaction. The meanings of R7, R10, R11, R13, R17 and R17? as well as of the grouping U-V-W-X-Y-Z are indicated in the claims.
    Type: Application
    Filed: July 24, 2003
    Publication date: April 28, 2005
    Applicant: Schering AG
    Inventors: Ludwig Zorn, Rolf Bohlmann, Norbert Gallus, Hermann Kuenzer, Hans-Peter Muhn, Reinhard Nubbemeyer