Patents by Inventor Norbert Hoefgen

Norbert Hoefgen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing high-purity hydroxyindolylglyoxylamides
    Patent number: 7122674
    Abstract: The invention relates to a process for preparing hydroxyindolylglyoxylamides in high yields and particularly pure form.
    Type: Grant
    Filed: July 31, 2003
    Date of Patent: October 17, 2006
    Assignee: Elbion AG
    Inventors: Hans-Joachim Jänsch, Helge Hartenhauer, Hans Stange, Norbert Höfgen, Jürgen Schäfer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6613794
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: January 20, 2003
    Date of Patent: September 2, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6602890
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: August 5, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6545158
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: April 8, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and processes for their preparation
    Patent number: 6545025
    Abstract: The invention relates to nets hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: February 21, 2002
    Date of Patent: April 8, 2003
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • Process for the treatment of erectile dysfunction and product therefor
    Patent number: 6465465
    Abstract: The invention relates to the use of pyrido[3,2-e]-pyrazinones of formula 1 as inhibitors of phosphodiesterase 5 for the treatment of erectile dysfunction (impotence).
    Type: Grant
    Filed: February 8, 2001
    Date of Patent: October 15, 2002
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Degenhard Marx, Norbert Höfgen, Ute Egerland, Stefan Szelényi, Thomas Kronbach
  • Use of maduraohtalazine derivatives as inhibitors of proinflammatory cytokines
    Patent number: 6440968
    Abstract: The maduraphthalazine derivatives of the formula (4) are able to inhibit the effect of the cytokines interleukin-2, interleukin-4 and interleukin-5 and are suitable for the production of pharmaceuticals.
    Type: Grant
    Filed: April 13, 2000
    Date of Patent: August 27, 2002
    Assignee: Elbion G.m.b.H.
    Inventors: Regina Draheim, Thomas Kronbach, Lothar Heinisch, Ernst Roemer, Norbert Höfgen, Hildegard Poppe, Peter Jütten, Wolfgang Haas, Walter Werner, Udo Gräfe
  • Hydroxyindoles, their use as inhibitors of phosphodiesterase 4 and process for their preparation
    Patent number: 6251923
    Abstract: The invention relates to new hydroxyindoles of the Formula, their use as inhibitors of phosphodiesterase 4 and processes for their preparation.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: June 26, 2001
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Norbert Höfgen, Ute Egerland, Hildegard Poppe, Degenhard Marx, Stefan Szelényi, Thomas Kronbach, Emmanuel Polymeropoulos, Sabine Heer
  • 1,2,5-trisubstituted 1,2-dihydroindazol-3-ones having anti-asthmatic, anti-allergic, anti-inflammatory, immunomodulating and neuroprotective action, process for their preparation and their use as medicaments
    Patent number: 6180637
    Abstract: The invention relates to 1,2,5-trisubstituted 1,2-dihydroindazol-3-ones of formula (I) wherein X is —SO2—, —SO—, —(CH2)p—, —(CH2)p—O—, —(CH2)p—(C═O)—, —(CH2)p—(C═O)—NH—, —(CH2)p—CHOH—, —CHOH—(CH2)p—, —(CH2)p—CH═CH—, —CH═CH—(CH2)p—, Y is —(C═O)—, —(C═O)—NH—, —(C═O)—NH—(CH2)p—, —C═O)—(CH2)p—, —(CH2)p—, —(CH2)p—O—, —(CH2)p—(C═O)—, —(CH2)p—(C═O)—NH—, —(CH2)p—(C═O)—NH—(CH2)p—, —(CH2)p—CHOH—, —CHOH—(CH2)p—, —(CH2)p—CH═CH—, —CH═CH—(CH2)p—, Z is —O—, —O—(CH2)p—, —NH—, —NH—(
    Type: Grant
    Filed: May 5, 1999
    Date of Patent: January 30, 2001
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Rudolf Schindler, Norbert Höfgen, Hildegard Poppe, Kay Brune