Abstract: A vehicle includes a drive motor with electrically upstream electric converter, a drive controller generating converter control signals actuating the converter for driving and normal braking operation, and an immobilizer electrically connected between the converter and the drive controller preventing converter control signals which would produce a driving operation of the drive motor from being forwarded to the converter when the vehicle is stopped, in particular at a stop. An alternate regulating device and a monitoring device allow activation of a special braking mode in the presence of an emergency braking command and in the event of which the drive controller is deactivated or at least signal flows of converter control signals of the drive controller to the immobilizer are interrupted, the immobilizer is activated, and converter control signals producing braking operation of the drive motor are transmitted to the converter through the immobilizer by the alternate regulating device.

Abstract: A vehicle includes a drive motor with electrically upstream electric converter, a drive controller generating converter control signals actuating the converter for driving and normal braking operation, and an immobilizer electrically connected between the converter and the drive controller preventing converter control signals which would produce a driving operation of the drive motor from being forwarded to the converter when the vehicle is stopped, in particular at a stop. An alternate regulating device and a monitoring device allow activation of a special braking mode in the presence of an emergency braking command and in the event of which the drive controller is deactivated or at least signal flows of converter control signals of the drive controller to the immobilizer are interrupted, the immobilizer is activated, and converter control signals producing braking operation of the drive motor are transmitted to the converter through the immobilizer by the alternate regulating device.

Abstract: The present invention is directed to new 5-ALA derivatives, particles and formulation thereof, related methods of preparation and methods of use thereof. In particular, the invention relates to compounds of the invention, particles and formulation thereof useful in the treatment of a cancer and/or the diagnosis of a cancer cell such as in photodynamic therapy or photodynamic diagnosis.

Abstract: The present invention is directed to new 5-ALA derivatives, particles and formulation thereof, related methods of preparation and methods of use thereof. In particular, the invention relates to compounds of the invention, particles and formulation thereof useful in the treatment of a cancer and/or the diagnosis of a cancer cell such as in photodynamic therapy or photodynamic diagnosis.

Abstract: A Hall sensor includes a first Hall element pair configured to provide a first measurement signal, a second Hall element pair configured to provide a second measurement signal, and a third Hall element pair configured to provide a third measurement signal. Each element in the third Hall element pair is arranged between Hall elements of the first Hall element pair and Hall elements of the second Hall element pair. The Hall element pairs are configured to be actuated such that the first, second, and third measurement signals can be combined into one aggregate measurement signal which corrects an error in an angle of rotation determination caused by an external magnetic field.

Abstract: A Hall sensor includes a first Hall element pair configured to provide a first measurement signal, a second Hall element pair configured to provide a second measurement signal, and a third Hall element pair configured to provide a third measurement signal. Each element in the third Hall element pair is arranged between Hall elements of the first Hall element pair and Hall elements of the second Hall element pair. The Hall element pairs are configured to be actuated such that the first, second, and third measurement signals can be combined into one aggregate measurement signal which corrects an error in an angle of rotation determination caused by an external magnetic field.

Abstract: A filter device for fluids, in particular for low viscosity fluids such as water, includes a filter housing (1) in which element holders (31) are provided for a plurality of filter elements (21). Filter medium (35) of each filter element in the filter housing (1) separates an unfiltered side (5) from a clean side (7). The filter housing (1) can be opened for inserting and removing the filter elements (21). A carrier in the form of a basket (19) is provided for the filter elements (21). The basket can be inserted into and removed from the filter housing (1). The filter elements (21) can be releasably secured at the basket.

Abstract: A method for functionally checking a vacuum switch of a traction inverter having a grid-side four-quadrant chopper and a load-side pulse inverter electrically connected in parallel on the DC side by a DC intermediate circuit. The AC side of the chopper is connected to a secondary winding of a traction transformer, with the primary winding of the traction transformer connectable to an AC grid voltage by a vacuum switch. When the vacuum switch is open, the chopper is actuated precisely when the AC grid voltage is temporally located relative to the chopper input voltage, such that the amplitude of a voltage difference between the AC grid voltage and the chopper input voltage corresponds to a predetermined test voltage. It is then checked whether current flows from the AC supply grid to the chopper. The functionality of the vacuum switch can thus be checked at any time without a test device.

Abstract: A device for the pulsed release of an amount of fluid stored in a storage housing (2) has a locking device (7) formed by a piston-cylinder arrangement (8). The arrangement has a cylinder housing (9) subdivided into a first working chamber (11) and a second working chamber (12) by a working piston (10). An electrorheological or magnetorheological valve (14) in the form of a gap (15) or an opening is arranged between the working chambers (11, 12) in the circumference (13) of the working piston (10) or in the working piston (10).

Abstract: A device for the pulsed release of an amount (3) of fluid that is stored in a storage housing (2) includes a piston (5) biased by a first spring (4) and movable within the storage housing (2) to dispense the fluid by the spring bias, when triggered by an actuator (6) to release a lock holding the piston in place (7). The lock (7) has individual catches (8) keeping the piston (5) in its pretensioned position and, when actuated by the actuator (6), releases the piston (5).

Abstract: A vessel, particularly a pressure vessel, has a tubular housing part (10) in which a cover part (12) can be secured. Support segments (18) are inserted at least in some areas in a recess (14) on the interior (16) of the housing part (10). These segments provide support to the cover part (12) when it is installed. At least one fixing device (22) ensures a releasable engagement between cover part (12) and at least one of the support segments (18).

Abstract: A filter device for fluids, in particular for low viscosity fluids such as water, comprising a filter housing (1) in which element holders (31) are provided for a plurality of filter elements (21), whose filter medium (35) in the filter housing (1) separates an unfiltered side (5) from a clean side (7), wherein the filter housing (1) can be opened for the purpose of inserting and removing the filter elements (21), is characterized in that a carrier in the form of a basket (19) is provided for the filter elements (21), said basket can be inserted into and removed from the filter housing (1), and the filter elements (21) can be releasably secured at said basket.

Abstract: This invention relates to dry pharmaceutical compositions comprising an active ingredient which is 5-aminolevulinic acid (5-ALA) or a precursor or derivative of 5-ALA, or a pharmaceutically acceptable salt thereof. The compositions may be used in the photodynamic treatment (PDT) or photodynamic diagnosis (PDD) of cancer, pre-cancerous conditions and non-cancerous conditions. The invention relates further to irradiation devices comprising dry compositions and the use of such devices in the photodynamic treatment (PDT) or photodynamic diagnosis (PDD) of cancer, pre-cancerous conditions and non-cancerous conditions.

Abstract: A method for hair removal from a skin area by selective photo-inactivation of the pilo-sebaceous apparatus using derivatives of ALA with alkylene-glycol chains. Selectivity of the method is further enhanced by treatment of the epidermis by agents reducing PpIX levels in the epidermis. Side effects are diminished by using short drug/light intervals.

Abstract: 1. Device for the pulsed release of an amount of fluid (3) which can be stored in an accumulator housing (2). 2. A device for the pulsed release of an amount of fluid which can be stored in a storage housing (2) is characterized in that a locking device (7) is formed by a piston-cylinder arrangement (8) having a cylinder housing (9) that is subdivided into a first working chamber (11) and a second working chamber (12) by a working piston (10), an electrorheological or magnetorheological valve (14) in the form of a gap (15) or an opening being arranged between the working chambers (11, 12) in the circumference (13) of the working piston (10) or in the working piston (10) as such.

Abstract: The invention relates to a vessel, particularly a pressure vessel, having a tubular housing part (10), in which a cover part (12) can be secured, characterized in that support segments (18) are inserted at least in some areas in a recess (14) on the interior (16) of the housing part (10), which segments provide support to the cover part (12) when it is installed, and that at least one fixing means (22) is provided, which ensures a releasable engagement between cover part (12) and at least one of the support segments (18).

Abstract: A method for functionally checking a vacuum switch of a traction inverter having a grid-side four-quadrant chopper and a load-side pulse inverter electrically connected in parallel on the DC side by a DC intermediate circuit. The AC side of the chopper is connected to a secondary winding of a traction transformer, with the primary winding of the traction transformer connectable to an AC grid voltage by a vacuum switch. When the vacuum switch is open, the chopper is actuated precisely when the AC grid voltage is temporally located relative to the chopper input voltage, such that the amplitude of a voltage difference between the AC grid voltage and the chopper input voltage corresponds to a predetermined test voltage. It is then checked whether current flows from the AC supply grid to the chopper. The functionality of the vacuum switch can thus be checked at any time without a test device.

Abstract: A device for the pulsed release of an amount (3) of fluid that is stored in a storage housing (2), in particular for implementing a start-stop function in automatic transmissions, with a piston (5) that is supported against a first energy storage device (4) and that, with the capacity to move within the storage housing (2), limits in conjunction with the latter the amount (3) of fluid that can be held and that, when triggered by an actuation means (6) and released by a locking means (7), pushes the amount (3) of fluid out of the storage housing (2) in a pulsed manner, the locking means (7) having individual catch means (8) that in the locked position keep the piston (5) in its pretensioned position, and that, when actuated by the actuation means (6), release the piston (5) in a release position, is characterized in that in any travel position of the piston (5), the catch means (8) are at least partially in contact with the inside wall of the piston (5) facing them, and that for locking of the piston (5), the

Abstract: Methods and compositions involving enzyme-activatable fluorophore polymer imaging agents for photodetection of specific tissues and/or human diseases and disorders are provided. In certain embodiments, the imaging agent comprises a hydrophilic polymer backbone (e.g., poly(L)lysine), a hydrophobic fluorophore, and a hydrophilic solubilizing agent. The solubilizing agent may comprise a quarternary ammonium group (e.g., a 1-methylnicotinic group) to enhance self-quenching of the fluorophore. Various methods for the generation and purification of imaging agents are also provided, including methods involving solid phase probe extraction or ion exchange purification.

Abstract: A filter device includes a filter housing (10), a filter inlet (12), a filter outlet (14), and a filter element (16). The filter element divides a filter area (18) into two partial areas (20, 22). One partial filter areas is conical in form with the cross-section of that partial area (20) being tapered from the filter inlet (12) to the filter outlet (14). The partial areas are separated from each other by the filter element. This arrangement results in an optimum residence time distribution inside the filter device at a uniform flow rate, which is particularly useful for highly viscous fluids such as polymer melts or similar.