Patents by Inventor Norbert Lui

Norbert Lui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for producing 2,2-difluoroethylamine derivative by amide hydrogenation
    Patent number: 8273897
    Abstract: Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are reduced to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A radical is as defined in the description:
    Type: Grant
    Filed: September 5, 2008
    Date of Patent: September 25, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Stefan Antons
  • Process for preparing 2-dihaloacyl-3-aminoacrylic acid derivatives
    Patent number: 8258335
    Abstract: The present invention relates to a process for preparing hydrochloride-free 2-dihaloacyl-3-aminoacrylic esters by reacting acid fluorides with dialkylaminoacrylic acid derivatives.
    Type: Grant
    Filed: September 13, 2008
    Date of Patent: September 4, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Sergii Pazenok, Norbert Lui
  • Alkoxy enones and enamino ketones and a process for preparation thereof
    Patent number: 8242313
    Abstract: The present invention relates to novel alkoxy enones and enamino ketones, and to a novel process for preparation thereof. Alkoxy enones and enamino ketones are valuable intermediates for preparation of pyrazoles and anthranilamides, which can be used as insecticides.
    Type: Grant
    Filed: January 21, 2011
    Date of Patent: August 14, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Sergii Pazenok, Norbert Lui, Arnd Neeff
  • Process for preparing 2,2-difluoroethylamine and salts thereof proceeding from difluoroacetonitrile
    Patent number: 8242311
    Abstract: The present invention relates to a process for preparing 2,2-difluoroethylamine of the formula (I) and salts thereof, for example sulphates, hydrochlorides or acetates, which proceeds from difluoroacetonitrile.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: August 14, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Stefan Antons, Wahed Ahmed Moradi
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE
    Publication number: 20120190867
    Abstract: A process for the preparation of 2,2-difluoroethylamine, comprising the reaction of 2,2-difluoro-1-chloroethane with an imide of the formula (II) in the presence of an acid scavenger, to give a compound of the formula (III) in which, in the compounds of the formulae (II) and (III), R1 and R2 are, each independently of one another, hydrogen or C1-C6-alkyl or R1 and R2 form, together with the carbon atoms to which they are bonded, a six-membered aromatic ring which is optionally substituted; and the cleavage of 2,2-difluoroethylamine by reaction of the compound of the formula (III) with acid, base or hydrazine.
    Type: Application
    Filed: January 23, 2012
    Publication date: July 26, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH
  • PROCESS FOR PREPARING 2,2-DIFLUOROETHYLAMINE FROM 2,2-DIFLUORO-1-CHLOROETHANE AND AMMONIA
    Publication number: 20120184777
    Abstract: Process for preparing 2,2-difluoroethylamine, comprising the following steps: (i) mixing 2,2-difluoro-1-chloroethane and gaseous, liquid or supercritical ammonia in a pressure-stable, closed reaction vessel under a pressure in the range from 10 to 180 bar; (ii) reacting the reaction mixture at a reaction temperature in the range from 80° C. to 200° C.; (iii) letting down the reaction mixture and isolating 2,2-difluoroethylamine.
    Type: Application
    Filed: January 11, 2012
    Publication date: July 19, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Rafael WARSITZ, Christian FUNKE, Christian SEVERINS
  • Dioxolane and dioxane derivatives and a process for their preparation
    Patent number: 8222435
    Abstract: The present invention relates to novel acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes of the general formula (I) in which R1, R2, R3 and n have the meanings given in the description, and also a novel process for their preparation. Acylmethylene-1,3-dioxolanes and acylmethylene-1,4-dioxanes are important intermediates for the preparation of pyrazoles and anthranilamides, which can be used as insecticides.
    Type: Grant
    Filed: December 15, 2010
    Date of Patent: July 17, 2012
    Assignee: Bayer CropScience AG
    Inventors: Sergii Pazenok, Norbert Lui, Igor Gerus, Olga Balabon
  • Process for preparing fluoroalkyl nitriles
    Patent number: 8203015
    Abstract: The present invention relates to a process for preparing fluoroalkyl nitriles by reacting fluorinated carboxamides with halides and fluorinated carboxylic acids.
    Type: Grant
    Filed: June 7, 2010
    Date of Patent: June 19, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich, Thomas Wollner, Sergii Pazenok
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM PROP-2-EN-1-AMINE
    Publication number: 20120142971
    Abstract: A process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2??(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the formula (II) CHF2—CH2Hal??(II) in which Hal is chlorine, bromine or iodine, with prop-2-en-1-amine of the formula (III) to give N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (IV) preferably in the presence of an acid scavenger, and stage (ii): removal of the allyl group from the N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (IV) obtained in stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.
    Type: Application
    Filed: November 9, 2011
    Publication date: June 7, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Christian FUNKE, Jens-Dietmar HEINRICH, Thomas Norbert MÜLLER
  • PROCESS FOR PREPARING PYRIDYL-SUBSTITUTED PYRAZOLES
    Publication number: 20120136156
    Abstract: The present invention relates to a process for preparing 1-pyridyl-substituted pyrazoles, comprising the reaction of acetyleneketones with pyridylhydrazine derivatives to give 1-pyridyl-substituted dihydro-1H-pyrazoles, the further reaction thereof with elimination of water to give 1-pyridyl-substituted trihalomethylpyrazoles, and the further processing thereof.
    Type: Application
    Filed: April 2, 2010
    Publication date: May 31, 2012
    Applicant: Bayer CropScience AG
    Inventors: Sergii PAZENOK, Norbert LUI, Harry BLASCHKE
  • Process for preparing 2,2-difluoroethylamine
    Patent number: 8188319
    Abstract: The present invention relates to a process for preparing 2,2-difluoroethylamine proceeding from 2,2-difluoro-1-haloethane using ammonia in a solvent which has a maximum water content of 15% by volume and in the presence of a catalyst which accelerates the reaction with ammonia.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: May 29, 2012
    Assignee: Bayer CropScience AG
    Inventors: Norbert Lui, Sergii Pazenok, Yuriy Grigorievich Shermolovich
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE DERIVATIVES STARTING FROM N-(2,2-DIFLUOROETHYL)PROP-2-EN-1-AMINE
    Publication number: 20120123130
    Abstract: Process for the preparation of 2,2-difluoroethylamine derivatives of the formula (IV) comprising the steps (i) and (ii): step (i): reaction of N-(2,2-difluoroethyl)prop-2-en-1-amine of the formula (I) with a compound of the formula (II) A-CH2-E??(II) to give a compound of the formula (III) optionally in the presence of an inorganic or organic base, and step (ii): removal of the allyl group from the compound of the formula (III), in which, in the formulae (II), (III) and (IV), A and E have the meanings given in the description.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 17, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH
  • PROCESS FOR THE PREPARATION OF 2,2-DIFLUOROETHYLAMINE STARTING FROM A BENZYLAMINE COMPOUND
    Publication number: 20120123163
    Abstract: Process for the preparation of 2,2-difluoroethylamine of the formula (I) CHF2CH2NH2??(I) comprising the stages (i) and (ii): stage (i): reaction of 2,2-difluoro-1-haloethane of the general formula (II) CHF2—CH2Hal??(II), with a benzylamine compound of the formula (III) in the presence of an acid scavenger, in which, in formula (II), Hal is chlorine, bromine or iodine, and, in the formulae (III), R1 is hydrogen or C1-C12-alkyl, and R2 is hydrogen, halogen, C1-C12-alkyl or C1-C6-alkoxy; stage (ii): catalytic hydrogenation of the N-benzyl-2,2-difluoroethanamine compound obtained in the stage (i) to give 2,2-difluoroethylamine of the formula (I) or a salt thereof.
    Type: Application
    Filed: November 9, 2011
    Publication date: May 17, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert LUI, Jens-Dietmar HEINRICH, Christian FUNKE, Günter SCHLEGEL, Thomas Norbert Müller
  • PROCESS FOR PREPARING TETRAZOLE-SUBSTITUTED ANTHRANILAMIDE DERIVATIVES AND NOVEL CRYSTAL POLYMORPHS OF THESE DERIVATIVES
    Publication number: 20120101133
    Abstract: The present invention relates to a process for preparing tetrazole-substituted anthranilamide derivatives of the formula (I) in which R1, R2, R3, R4, R5 and Z are each as defined in the description, and to a novel crystal polymorph of these derivatives and to the use thereof in agrochemical formulations.
    Type: Application
    Filed: June 14, 2011
    Publication date: April 26, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Sergii PAZENOK, Norbert Lui, Frank Volz, Britta Olenik, Christian Funke, Rüdiger Fischer, Oliver Gaertzen, Martin-Holger Hinz, Arnd Neeff
  • FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES
    Publication number: 20120065164
    Abstract: The present invention relates to pyrazole carboxamides derivatives of formula (1) wherein Y represents CR5 or N, T represents S or O, X1 and X2 represent a chlorine or a fluorine atom, and Z1 represents a substituted or non-substituted cyclopropyl; Their process of preparation, their use as fungicide, and/or anti-mycotoxin active agents, and/or insecticide, and/or nematicide, particularly in the form of fungicide compositions, and methods for the control of phytopathogenic fungi, notably of plants, using these compounds or compositions.
    Type: Application
    Filed: May 12, 2010
    Publication date: March 15, 2012
    Inventors: Guenter Bartels, Angela Becker, Juergen Benting, Christoph-Andreas Braun, Peter Dahmen, Philippe Desbordes, Christophe Dubost, Stephanie Gary, Ulrich Gorgens, Hiroyuki Hadano, Benoit Hartmann, Thomas Knobloch, Marc Kosten, Norbert Lui, Ruth Meissner, Sergiy Pazenok, Rachel Rama, Arnd Voerste, Ulrike Wachendorf-Neumann
  • Process for the Preparation of 5-Substituted 3-Aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles
    Publication number: 20120029202
    Abstract: The present invention relates to a process for the manufacturing of 5-substituted 3-aryl-3-(trifluoromethyl)-3,4-dihydro-2H-pyrroles of formula (I) which comprises the following steps: (i) reacting a compound of formula (II) with a isonitrile compound of formula (III) in the presence of a metal catalyst to obtain compounds of formula (IV) (ii) isomerizing compounds of formula (IV) to obtain compounds of formula (V) and (iii) reacting the dihydropyrrole compound of formula (V) under acidic conditions, to obtain the compounds of formula (I), wherein X, n, Z, Y, and T are as defined in the description.
    Type: Application
    Filed: May 11, 2011
    Publication date: February 2, 2012
    Applicant: Bayer CropScience AG
    Inventors: Koichi ARAKI, Jun Mihara, Norio Sasaki, Peter Bruechner, Kei Domon, Johannes-Rudolf Jansen, Norbert Lui
  • Novel alkoxy enones and enamino ketones and a process for preparation thereof
    Publication number: 20120022285
    Abstract: The present invention relates to novel alkoxy enones and enamino ketones, and to a novel process for preparation thereof. Alkoxy enones and enamino ketones are valuable intermediates for preparation of pyrazoles and anthranilamides, which can be used as insecticides.
    Type: Application
    Filed: January 21, 2011
    Publication date: January 26, 2012
    Applicant: Bayer CropScience AG
    Inventors: Sergii Pazenok, Norbert Lui, Arnd Neeff
  • METHOD FOR PRODUCING 2,2 DIFLUOROETHYLAMINE DERIVATIVES BY IMINE HYDROGENATION
    Publication number: 20120022264
    Abstract: Process for preparing 2,2-difluoroethylamine derivatives, wherein compounds of the general formula (IV) are hydrogenated to the corresponding 2,2-difluoroethylamine derivatives of the general formula (III), where the A, R1 and R2 radicals are each as defined in the description:
    Type: Application
    Filed: March 8, 2010
    Publication date: January 26, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert Lui, Stefan Antons
  • NOVEL METHOD FOR PRODUCING ENAMINOCARBONYL COMPOUNDS
    Publication number: 20120016132
    Abstract: The present invention relates to a process for the preparation of enaminocarbonyl compounds of the formula (I) where compounds of the formula (II) are reacted in the presence of a Brønsted acid to give compounds of the formula (I), and A, R1 and Z are as defined in the description, and also corresponding starting compounds which are used in the process according to the invention.
    Type: Application
    Filed: March 12, 2010
    Publication date: January 19, 2012
    Applicant: BAYER CROPSCIENCE AG
    Inventors: Norbert Lui, Jens-Dietmar Heinrich
  • Stereoselective one step fluorination process for the preparation of 2-flouropropionate
    Patent number: 8093421
    Abstract: The current invention describes a one-step process for the synthesis of 2-fluoropropionates from lactic acid ester derivatives using TFEDMA.
    Type: Grant
    Filed: October 16, 2007
    Date of Patent: January 10, 2012
    Assignee: Bayer Cropscience AG
    Inventors: Norbert Lui, Sergii Pazenok