Patents by Inventor Norbert Mesterházy

Norbert Mesterházy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROCESS FOR PREPARATION OF HIGH-PURITY MELOXICAM AND MELOXICAM POTASSIUM SALT
    Publication number: 20120035162
    Abstract: The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam.
    Type: Application
    Filed: October 12, 2011
    Publication date: February 9, 2012
    Inventors: Tibor MEZEI, Gyula Simig, Enikó Molnár, Gyula Lukács, Márta Porcs-Makkay, Balázs Volk, Valéria Hofmanné Fekete, Kálmán Nagy, Norbert Mesterházy, György Krasznai, Györgyi Vereczkeyné Donáth, Gyuláné Körtvélyessy, Éva Pécsi
  • Process for preparation of high-purity meloxicam and meloxicam potassium salt
    Patent number: 8097616
    Abstract: The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium sait monohydrate is produced. Said sait is subsequently treated with mineral or organic acid to yield high-purity meloxicam.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: January 17, 2012
    Assignee: Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag
    Inventors: Tibor Mezei, Gyula Simig, Enikó Molnár, Gyula Lukács, Márta Porcs-Makkay, Balázs Volk, Valéria Hofmanné Fekete, Kálmán Nagy, Norbert Mesterházy, György Krasznai, Györgyi Vereczkeyné Donáth, Gyuláné Körtvélyessy, Éva Pécsi
  • Process for the preparation of olanzapine
    Patent number: 7981884
    Abstract: The invention relates to a process for the preparation of 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno-[2,3-b][1,5]benzodiazepine (olanzapine) of the formula (I) by reacting 4-amino-2-methyl-10H-thieno[2,3-b][1/5]benzodiazepine hydrochloride of the formula (II) with N-methylpiperazine in an organic solvent, which comprises carrying out the reaction in the mixture of toluene and 1,3-dimethyl-2-imidazolidinone. The invention also encompasses new 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b] [1,5]benzodiazepine dihydrochloride trihydrate of the formula (IB), the preparation thereof and pharmaceutical compositions comprising said new compound.
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: July 19, 2011
    Assignee: Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag
    Inventors: Györgyi Kovanyine Lax, Gábor Nemeth, György Krasznay, Norbert Mesterhazy, Kálmán Nagy, Györgyi Vereczkeyné Donáth, Zsuzsanna Szent-Kirallyi
  • Process for Preparation of High-Purity Meloxicam and Meloxicam Potassium Salt
    Publication number: 20090215757
    Abstract: The invention provides a process for the preparation of high purity meloxicam of the Formula (II). The meloxicam raw product is reacted with the solution of potassium hydroxide or potassium carbonate, whereby high purity meloxicam potassium salt monohydrate is produced. Said salt is subsequently treated with mineral or organic acid to yield high-purity meloxicam.
    Type: Application
    Filed: December 16, 2005
    Publication date: August 27, 2009
    Inventors: Tibor Mezei, Gyula Simig, Enikó Molnár, Gyula Lukács, Márta Porcs-Makkay, Balázs Volk, Valéria Hofmanné Fekete, Kálmán Nagy, Norbert Mesterházy, György Krasznai, Györgyi Vereczkeyné Donáth, Gyuláné Körtvélyessy, Éva Pécsi
  • PROCESS FOR THE PREPARTION OF OLANZAPINE
    Publication number: 20090137563
    Abstract: The invention relates to a process for the preparation of 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno-[2,3-b][1,5]benzodiazepine (olanzapine) of the formula (I) by reacting 4-amino-2-methyl-10H-thieno [2,3-b][1/5]benzodiazepine hydrochloride of the formula (II) with N-methylpiperazine in an organic solvent, which comprises carrying out the reaction in the mixture of toluene and 1,3-dimethyl-2-imidazolidinone. The invention also encompasses new 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno [2,3-b][1,5]benzodiazepine dihydrochloride trihydrate of the formula (IB), the preparation thereof and pharmaceutical compositions comprising said new compound.
    Type: Application
    Filed: November 10, 2006
    Publication date: May 28, 2009
    Inventors: Gyorgyi Kovanyine Lax, Gabor Nemeth, Gyorgy Krasznay, Norbert Mesterhazy, Kalman Nagy, Gyorgyi Vereczkeyne Donath, Zsuzsanna Szent-Kirallyi