Patents by Inventor Norbert Neuss

Norbert Neuss has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing deoxynarasin antibiotics
    Patent number: 4204039
    Abstract: Deoxynarasin antibiotic complex, comprising 20-deoxynarasin and 20-deoxy-epi-17-narasin, is produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 11181. 20-Deoxynarasin and 20-deoxy-epi-17-narasin are separated and isolated by chromatography. The deoxynarasin complex, 20-deoxynarasin and 20-deoxy-epi-17-narasin are antibacterial and anticoccidial agents and also increase feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: June 19, 1978
    Date of Patent: May 20, 1980
    Assignee: Eli Lilly and Company
    Inventors: Walter M. Nakatsukasa, Gary G. Marconi, Norbert Neuss, Robert L. Hamill
  • Apparatus and method for coordinating chromatographic separation (HPLC) with UV/VIS absorbency values and with bioautograph test results
    Patent number: 4174772
    Abstract: An apparatus is described which is adaptable for use in coordinating UV/VIS absorbency values of a chromatography eluate containing antimicrobial constituents with bioautograph test results. Such an apparatus is comprised of a UV/VIS spectrophotometer equipped with a continuous recording monitor, a pair of parallel metering valves, a stream splitter, a rotatable drum adapted to hold a piece of absorbent material and means to rotate said drum. The method involves the use of such an apparatus in combination with the bioautograph test to coordinate said absorbency valves with the test results from a plurality of bioautograph test organisms.
    Type: Grant
    Filed: December 28, 1977
    Date of Patent: November 20, 1979
    Assignee: Eli Lilly and Company
    Inventors: Norbert Neuss, Roger D. Miller
  • Deoxynarasin antibiotics
    Patent number: 4174404
    Abstract: Deoxynarasin antibiotic complex, comprising 20-deoxynarasin and 20-deoxy-epi-17-narasin, is produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 11181. 20-Deoxynarasin and 20-deoxy-epi-17-narasin are separated and isolated by chromatography. The deoxynarasin complex, 20-deoxynarasin and 20-deoxy-epi-17-narasin are antibacterial and anticoccidial agents and also increase feed-utilization efficiency in ruminants. 20-Deoxynarasin and its salts are cardiotonic agents.
    Type: Grant
    Filed: October 27, 1978
    Date of Patent: November 13, 1979
    Assignee: Eli Lilly and Company
    Inventors: Walter M. Nakatsukasa, Gary G. Marconi, Norbert Neuss, Robert L. Hamill
  • Deoxynarasin antibiotics
    Patent number: 4141907
    Abstract: Deoxynarasin antibiotic complex, comprising 20-deoxynarasin and 20-deoxy-epi-17-narasin, is produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 11181. 20-Deoxynarasin and 20-deoxy-epi-17-narasin are separated and isolated by chromatography. The deoxynarasin complex, 20-deoxynarasin and 20-deoxy-epi-17-narasin are antibacterial and anticoccidial agents and also increase feed-utilization efficiency in ruminants.
    Type: Grant
    Filed: October 20, 1977
    Date of Patent: February 27, 1979
    Assignee: Eli Lilly and Company
    Inventors: Walter M. Nakatsukasa, Gary G. Marconi, Norbert Neuss, Robert L. Hamill
  • 4-Desacetoxy-4-oxovinblastine
    Patent number: 4122082
    Abstract: 4-Desacetoxy-4-oxovinblastine, prepared by oxidation of 4-desacetylvinblastine, useful as an intermediate.
    Type: Grant
    Filed: November 7, 1977
    Date of Patent: October 24, 1978
    Assignee: Eli Lilly and Company
    Inventors: Ian G. Wright, Norbert Neuss
  • Des-N-methylvindoline
    Patent number: 4082754
    Abstract: Vindoline and vinblastine demethylated by submerged culture fermentation with S. albogriseolus.
    Type: Grant
    Filed: December 4, 1975
    Date of Patent: April 4, 1978
    Assignee: Eli Lilly and Company
    Inventors: Donald R. Brannon, Norbert Neuss
  • Conversion of leurosine to vincathicine
    Patent number: 4025522
    Abstract: Leurosine is converted to vincathicine by treatment with acid.
    Type: Grant
    Filed: January 14, 1976
    Date of Patent: May 24, 1977
    Assignee: Eli Lilly and Company
    Inventors: Norbert Neuss, Susan S. Tafur
  • N-demethylation of indole alkaloids by S. albogriseolus
    Patent number: 3989593
    Abstract: Vindoline and vinblastine demethylated by submerged culture fermentation with S. albogriseolus.
    Type: Grant
    Filed: September 19, 1973
    Date of Patent: November 2, 1976
    Assignee: Eli Lilly and Company
    Inventors: Donald R. Brannon, Norbert Neuss
  • Conversion of leurosine to vincathicine
    Patent number: 3968113
    Abstract: Leurosine is converted to vincathicine by treatment with acid.
    Type: Grant
    Filed: February 7, 1975
    Date of Patent: July 6, 1976
    Assignee: Eli Lilly and Company
    Inventors: Norbert Neuss, Susan S. Tafur
  • 4-Desacetoxyvinblastine
    Patent number: 3954773
    Abstract: 4-Desacetoxyvinblastine, a novel indole-dihydroindole alkaloid obtained in small quantities from Vinca rosea, intermediate for the preparation of antimitotic compounds.
    Type: Grant
    Filed: November 21, 1974
    Date of Patent: May 4, 1976
    Assignee: Eli Lilly and Company
    Inventors: Norbert Neuss, Albert J. Barnes