Patents by Inventor Noreen D. Francis

Noreen D. Francis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Extractive purification of lipopeptide antibiotics
    Patent number: 7138487
    Abstract: The present invention provides a rapid and inexpensive method for extractively isolating acidic lipopeptide antibiotics, such as those having a cyclic peptide or cyclic depsipeptide core, in high yield and purity. In particular, there is provided a method of extracting a variety of acidic lipopeptide antibiotics, directly or indirectly, into water immiscible organic solvents by using a divalent cation chelation procedure.
    Type: Grant
    Filed: March 26, 2004
    Date of Patent: November 21, 2006
    Assignee: Migenix Inc.
    Inventors: Donald B. Borders, Noreen D. Francis, Amedeo A. Fantini
  • Extractive purification of lipopeptide antibiotics
    Publication number: 20040242467
    Abstract: The present invention provides a rapid and inexpensive method for extractively isolating acidic lipopeptide antibiotics in high yield and purity.
    Type: Application
    Filed: March 26, 2004
    Publication date: December 2, 2004
    Applicant: MICROLOGIX BIOTECH INC.
    Inventors: Donald B. Borders, Noreen D. Francis, Amedeo A. Fantini
  • Derivatives of laspartomycin and preparation and use thereof
    Patent number: 6737403
    Abstract: The present invention provides laspartomycin core peptides, laspartomycin core peptide derivatives, antimicrobial laspartomycin derivatives, methods for making laspartomycin core peptides, methods for making laspartomycin core peptide derivatives, methods for making antimicrobial laspartomycin derivatives, pharmaceutical compositions of antimicrobial laspartomycin derivatives, methods of inhibiting microbial growth and methods for treating and/or preventing microbial infections in a subject.
    Type: Grant
    Filed: July 13, 2001
    Date of Patent: May 18, 2004
    Assignee: Micrologix Biotech Inc.
    Inventors: Donald B Borders, William V Curran, Amedeo A Fantini, Noreen D Francis, Howard Jarolmen, Richard A Leese
  • Extractive purification of lipopeptide antibiotics
    Patent number: 6716962
    Abstract: The present invention provides a rapid and inexpensive method for extractively isolating acidic lipopeptide antibiotics, such as those having a cyclic peptide or cyclic depsipeptide core, in high yield and purity. In particular, there is provided a method of extracting a variety of acidic lipopeptide antibiotics, directly or indirectly, into water immiscible organic solvents by using a divalent cation chelation procedure.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: April 6, 2004
    Assignee: Micrologix Biotech Inc.
    Inventors: Donald B Borders, Noreen D Francis, Amedeo A Fantini
  • Derivatives of laspartomycin and preparation and use thereof
    Patent number: 6511962
    Abstract: The present invention provides a laspartomycin core peptide, a laspartomycin core peptide derivative, a antimicrobial laspartomycin derivative, a method for making laspartomycin core peptides, methods for making laspartomycin core peptide derivatives, methods for making antimicrobial laspartomycin derivatives, pharmaceutical compositions of antimicrobial laspartomycin derivatives, methods of inhibiting microbial growth and methods for treating and/or preventing microbial infections in a subject.
    Type: Grant
    Filed: January 12, 2001
    Date of Patent: January 28, 2003
    Assignee: Micrologix Biotech Inc.
    Inventors: Donald B Borders, William V Curran, Amedeo A Fantini, Noreen D Francis, Howard Jarolmen, Richard A Leese
  • Extractive purification of lipopeptide antibiotics
    Publication number: 20020132762
    Abstract: The present invention provides a rapid and inexpensive method for extractively isolating acidic lipopeptide antibiotics in high yield and purity.
    Type: Application
    Filed: September 6, 2001
    Publication date: September 19, 2002
    Inventors: Donald B. Borders, Noreen D. Francis, Amedeo A. Fantini
  • Derivatives of laspartomycin and preparation and use thereof
    Publication number: 20020035063
    Abstract: The present invention provides laspartomycin core peptides, laspartomycin core peptide derivatives, antimicrobial laspartomycin derivatives, methods for making laspartomycin core peptides, methods for making laspartomycin core peptide derivatives, methods for making antimicrobial laspartomycin derivatives, pharmaceutical compositions of antimicrobial laspartomycin derivatives, methods of inhibiting microbial growth and methods for treating and/or preventing microbial infections in a subject.
    Type: Application
    Filed: July 13, 2001
    Publication date: March 21, 2002
    Inventors: Donald B. Borders, William V. Curran, Amedeo A. Fantini, Noreen D. Francis, Howard Jarolmen, Richard A. Reese