Patents by Inventor Noreen J. Hickok

Noreen J. Hickok has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotic drug release sheath
    Patent number: 10485902
    Abstract: An implantable medical device having a sheath formed of a polymer material, wherein the sheath forms a reservoir attached to or around the implantable medical device, and wherein the reservoir is sealed with a biocompatible pressure responsive coating; wherein the biocompatible coating is stable for at least 7-day post implantation into a body, and can be mechanically ruptured by application of an exterior pressure generating force.
    Type: Grant
    Filed: August 29, 2016
    Date of Patent: November 26, 2019
    Assignees: Thomas Jefferson University, Drexel University
    Inventors: Christopher K. Kepler, Alex Michael Sevit, Steven Michael Kurtz, Noreen J. Hickok, Flemming Forsberg, John R. Eisenbrey
  • COVALENT MODIFICATION OF DECELLULARIZED ALLOGENEIC GRAFTS WITH ACTIVE PHARMACEUTICALS
    Publication number: 20180303976
    Abstract: A functionalized tissue having covalently bound antibiotics and methods for producing the functionalized tissue having bound antibiotics comprising; providing a tissue having a sufficient number of primary amine groups on the tissue; coupling and deprotecting one or more F-moc AEEA linkers using HATU chemistry to the primary amine groups; and coupling an antibiotic to said AEEA linkers using HATU chemistry.
    Type: Application
    Filed: October 3, 2016
    Publication date: October 25, 2018
    Applicant: THOMAS JEFFERSON UNIVERSITY
    Inventors: Noreen J. Hickok, Constantinos Ketonis, Javad Parvizi, Irving M. Shapiro, Christopher S. Adams, John A. Abraham
  • Multifunctional chitosan grafted surfaces and uses thereof
    Patent number: 9950097
    Abstract: The invention relates to a multifunctional chitosan grafted surface. Specifically, the invention relates to a chitosan modified with a quaternary ammonium salt (CH-Q) grafted surface that provides various functional properties, including stability (pH 3-9) and unique pH dependent swelling and antibacterial properties.
    Type: Grant
    Filed: February 7, 2012
    Date of Patent: April 24, 2018
    Assignees: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA, THOMAS JEFFERSON UNIVERSITY
    Inventors: Hyun-Su Lee, Russell Composto, David M. Eckmann, Noreen J. Hickok
  • ANTIBIOTIC DRUG RELEASE SHEATH
    Publication number: 20170056565
    Abstract: An implantable medical device having a sheath formed of a polymer material, wherein the sheath forms a reservoir attached to or around the implantable medical device, and wherein the reservoir is sealed with a biocompatible pressure responsive coating; wherein the biocompatible coating is stable for at least 7-day post implantation into a body, and can be mechanically ruptured by application of an exterior pressure generating force.
    Type: Application
    Filed: August 29, 2016
    Publication date: March 2, 2017
    Applicants: Thomas Jefferson University, Drexel University
    Inventors: Christopher K. Kepler, Alex Michael Sevit, Steven Michael Kurtz, Noreen J. Hickok, Flemming Forsberg, John R. Eisenbrey
  • MULTIFUNCTIONAL CHITOSAN GRAFTED SURFACES AND USES THEREOF
    Publication number: 20140114055
    Abstract: The invention relates to a multifunctional chitosan grafted surface. Specifically, the invention relates to a chitosan modified with a quaternary ammonium salt (CH-Q) grafted surface that provides various functional properties, including stability (pH 3-9) and unique pH dependent swelling and antibacterial properties.
    Type: Application
    Filed: February 7, 2012
    Publication date: April 24, 2014
    Inventors: Hyun-Su Lee, Russell Composto, David M. Eckmann, Noreen J. Hickok