Patents by Inventor Noreen P. Nugent

Noreen P. Nugent has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteropolymeric protein production methods
    Patent number: 5674711
    Abstract: Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.
    Type: Grant
    Filed: July 23, 1993
    Date of Patent: October 7, 1997
    Assignee: Genzyme Corporation
    Inventors: Christie A. Kelton, Noreen P. Nugent, Scott C. Chappel
  • Heteropolymeric protein production methods
    Patent number: 5658760
    Abstract: Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: August 19, 1997
    Assignee: Genzyme Corporation
    Inventors: Christie A. Kelton, Noreen P. Nugent, Scott C. Chappel
  • Heteropolymeric protein production methods
    Patent number: 5602006
    Abstract: Cultured mammalian cell transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: February 11, 1997
    Assignee: Genzyme Corporation
    Inventors: Christie A. Kelton, Noreen P. Nugent, Scott C. Chappel
  • Heteropolymeric protein production methods
    Patent number: 5240832
    Abstract: Cultured mammalian cells transfected with new vectors comprising full-length or partial .alpha. and .beta. subunit genomic DNA sequences produce significantly higher levels of dimeric glycoprotein hormone than do cells transfected with .alpha. and .beta. subunit cDNA sequences. In cases where only the cDNA clones are available, the cDNA sequences can be used in new expression vectors comprising introns or other important genomic regions from a homologous or heterologous source.
    Type: Grant
    Filed: October 16, 1991
    Date of Patent: August 31, 1993
    Assignee: Genzyme Corporation
    Inventors: Christie A. Kelton, Noreen P. Nugent, Scott C. Chappel