Patents by Inventor Norifumi Tokunaga

Norifumi Tokunaga has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9457134
    Abstract: A surface treating agent comprising a copolymer including: a monomer (A) having a hydrophilic functional group of formula (1), a monomer (B) having a basic functional group of formula (3) or (5), and a monomer (C) having a reactive functional group of formula (7), wherein the copolymer has a molar ratio of the monomer (A)/the monomer (B)/and the monomer (C) between 87/10/3 and 98/1/1. In the formulas, the R groups and n are defined.
    Type: Grant
    Filed: October 7, 2015
    Date of Patent: October 4, 2016
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Shoji Ochiai, Norifumi Tokunaga, Noboru Taguchi
  • Publication number: 20160024240
    Abstract: A surface treating agent comprising a copolymer including: a monomer (A) having a hydrophilic functional group of formula (1), a monomer (B) having a basic functional group of formula (3) or (5), and a monomer (C) having a reactive functional group of formula (7), wherein the copolymer has a molar ratio of the monomer (A)/the monomer (B)/and the monomer (C) between 87/10/3 and 98/1/1. In the formulas, the R groups and n are defined.
    Type: Application
    Filed: October 7, 2015
    Publication date: January 28, 2016
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Shoji OCHIAI, Norifumi TOKUNAGA, Noboru TAGUCHI
  • Publication number: 20160023148
    Abstract: A surface treating agent comprising a copolymer including: a monomer (A) having a hydrophilic functional group of formula (2), a monomer (B) having a basic functional group of formula (3) or (5), and a monomer (C) having a reactive functional group of formula (8), wherein the copolymer has a molar ratio of the monomer (A)/the monomer (B)/and the monomer (C) between 87/10/3 and 98/1/1. In the formulas, the R groups and n are defined.
    Type: Application
    Filed: October 7, 2015
    Publication date: January 28, 2016
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Shoji OCHIAI, Norifumi TOKUNAGA, Noboru TAGUCHI
  • Patent number: 9186441
    Abstract: A surface treating agent includes a copolymer including: a monomer (A) having a hydrophilic functional group of formula (1) or (2) below, a monomer (B) having a basic functional group, and a monomer (C) having a reactive functional group as monomer components, wherein the copolymer has a molar ratio of the monomer (A)/the monomer (B)/and the monomer (C) being between 70/15/15 and 98/1/1. (wherein each of R1 represents a hydrogen atom or a methyl group, R2 represents an alkyl group having 1 to 4 carbon atoms, n represents an integer of 2 to 4, and each of R3 and R4 independently represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms).
    Type: Grant
    Filed: March 16, 2010
    Date of Patent: November 17, 2015
    Assignee: TERUMO KABUSHIKI KAISHA
    Inventors: Shoji Ochiai, Norifumi Tokunaga, Noboru Taguchi
  • Publication number: 20120024779
    Abstract: A surface treating agent is comprising a copolymer including: a monomer (A) having a hydrophilic functional group of formula (1) or (2) below, a monomer (B) having a basic functional group and a monomer (C) having a reactive functional group as monomer components, wherein the copolymer has a molar ratio of the monomer (A)/(B)/(C) between 70/15/15 to 98/1/1.
    Type: Application
    Filed: March 16, 2010
    Publication date: February 2, 2012
    Applicant: TERUMO KABUSHIKI KAISHA
    Inventors: Shoji Ochiai, Norifumi Tokunaga, Noboru Taguchi
  • Publication number: 20050148748
    Abstract: A copolymer having excellent blood compatibility comprising an alkoxyalkyl (meth)acrylate and a comonomer having a basic functional group, a surface treating agent for blood filter using the same, and blood filter coated with the same on the surface thereof. The copolymer is useful as blood filter material for efficiently removing leucocytes and platelets while preventing damages of blood components at the time of blood filtration to a low level.
    Type: Application
    Filed: February 10, 2005
    Publication date: July 7, 2005
    Applicant: Terumo Kabushiki Kaisha
    Inventors: Masaru Tanaka, Norifumi Tokunaga
  • Patent number: 6590054
    Abstract: A copolymer comprising a monomer of formula (1) below and a monomer having a basic functional group copolymerizable with the monomer as monomer components, wherein molar ratio of the monomer of formula (1) to the monomer having a basic functional group is 85/15 to 99.9/0.1 and wherein the copolymer has a number based mean molecular weight of 5,000 to 500,000. The copolymer is excellent in antithrombotic activity and further in biocompatibility and can be used as a medial material having high hydrophilicity. It also can serve as an antithrombotic surface treating agent. (wherein R1 is an alkylene group having 1 to 4 carbon atoms, R2 is an alkyl group having 1 to 4 carbon atoms, and R3 represents hydrogen or a methyl group).
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: July 8, 2003
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Masaru Tanaka, Shoji Ochiai, Norifumi Tokunaga, Yukiko Irie
  • Publication number: 20020064558
    Abstract: A copolymer comprising a monomer of formula (1) below and a monomer having a basic functional group copolymerizable with the monomer as monomer components, wherein molar ratio of the monomer of formula (1) to the monomer having a basic functional group is 85/15 to 99.9/0.1 and wherein the copolymer has a number based mean molecular weight of 5,000 to 500,000. The copolymer is excellent in antithrombotic activity and further in biocompatibility and can be used as a medial material having high hydrophilicity. It also can serve as an antithrombotic surface treating agent.
    Type: Application
    Filed: September 26, 2001
    Publication date: May 30, 2002
    Inventors: Masaru Tanaka, Shoji Ochiai, Norifumi Tokunaga, Yukiko Irie
  • Publication number: 20020000403
    Abstract: A copolymer having excellent blood compatibility comprising an alkoxyalkyl (meth)acrylate and a comonomer having a basic functional group, a surface treating agent for blood filter using the same, and blood filter coated with the same on the surface thereof. The copolymer is useful as blood filter material for efficiently removing leucocytes and platelets while preventing damages of blood components at the time of blood filtration to a low level.
    Type: Application
    Filed: May 17, 2001
    Publication date: January 3, 2002
    Inventors: Masaru Tanaka, Norifumi Tokunaga
  • Patent number: 6303375
    Abstract: A matrix for supporting cells such as animal cells is provided that enables cells to be supported at high efficiency and density in a short period. The matrix contains a plurality of cone shaped pores having an average diameter opening in an upstream surface of the matrix of from 500 to 1500 &mgr;m. The diameter decreases from the upstream surface to a downstream surface, and the average diameter of the cone shaped pores in the whole matrix is from 100 to 1000 &mgr;m. The matrix also contains a plurality of communicating pores that communicate with the cone shaped pores and with each other. These pores have an average diameter of from 5 to 100 &mgr;m, and the diameter decreases from a pore opening positioned near one surface of the matrix or near an interior surface of the cone shaped pores to a pore opening positioned remote from the surfaces. The matrix may also contain a plurality of column shaped pores having an average diameter of 100 to 1000 &mgr;m.
    Type: Grant
    Filed: June 23, 1999
    Date of Patent: October 16, 2001
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Tetsuhiro Kimura, Norifumi Tokunaga, Yoshitaka Omura