Patents by Inventor Norihiko Kondo

Norihiko Kondo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of screening for a substance that strengthens a bond between thioredoxin and macrophage migration inhibition factor
    Patent number: 8440413
    Abstract: Disclosed is a screening method which can select a substance having an influence on the binding between thioredoxin and MIF.
    Type: Grant
    Filed: November 26, 2009
    Date of Patent: May 14, 2013
    Assignee: Redox Bioscience, Inc.
    Inventors: Junji Yodoi, Norihiko Kondo, Aoi Son, Noriko Kato, Tomijiro Hara, Tomohisa Horibe
  • Screening method, composition containing substance selected by the screening method, and binding substance
    Publication number: 20120003673
    Abstract: Disclosed is a screening method which can select a substance having an influence on the binding between thioredoxin and MIF.
    Type: Application
    Filed: November 26, 2009
    Publication date: January 5, 2012
    Applicant: REDOX BIOSCIENCE, INC.
    Inventors: Junji Yodoi, Norihiko Kondo, Aoi Son, Noriko Kato, Tomijiro Hara, Tomohisa Horibe
  • MODIFIED THIOREDOXIN
    Publication number: 20100184215
    Abstract: The present invention relates to a human modified thioredoxin composed of any of the following polypeptides: (a) a polypeptide modified by alteration or chemical modification of a cysteine residue at position 35 with another amino acid in an amino acid sequence of SEQ ID NO:2; and (b) a polypeptide having an amino acid sequence having one or more substituted, deleted, inserted or added amino acids in positions except for positions 32 and 35, preferably positions 32 to 35 in the amino acid sequence of SEQ ID NO:2, and having an apoptosis-inducing activity.
    Type: Application
    Filed: January 25, 2010
    Publication date: July 22, 2010
    Inventors: YASUYUKI ISHII, JUNII YODOI, HAJIME NKAKMURA, NORIHIKO KONDO
  • PREVENTIVE OR THERAPEUTIC AGENT CONTAINING ANTI THIOREDOXIN ANTIBODY POLYPEPTIDE AS AN ACTIVE INGREDIENT FOR DISORDERS
    Publication number: 20090148464
    Abstract: The present invention provides a preventive or therapeutic agent being effective for disorders induced by macrophage migration inhibitory factor and vascular system disorders, and having fewer side effects. In particular, the present agent is characterized by containing anti TRX antibody polypeptide as an active ingredient to inhibit adherence of leukocyte to vascular endothelial cell and a cell internalization of the macrophage migration inhibitory factor.
    Type: Application
    Filed: February 19, 2008
    Publication date: June 11, 2009
    Inventors: Junji YODOI, Aoi Son, Norihiko Kondo, Hajime Nakamura, Tomijiro Hara, Noriko Kato
  • Modified Thioredoxin
    Publication number: 20090075871
    Abstract: The present invention relates to a human modified thioredoxin composed of any of the following polypeptides: (a) a polypeptide modified by alteration or chemical modification of a cysteine residue at position 35 with another amino acid in an amino acid sequence of SEQ ID NO:2; and (b) a polypeptide having an amino acid sequence having one or more substituted, deleted, inserted or added amino acids in positions except for positions 32 and 35, preferably positions 32 to 35 in the amino acid sequence of SEQ ID NO:2, and having an apoptosis-inducing activity.
    Type: Application
    Filed: September 29, 2005
    Publication date: March 19, 2009
    Applicant: National Institute of Advanced Industrial Science and Technology
    Inventors: Yasuyuki Ishii, Junji Yodoi, Hajime Nakamura, Norihiko Kondo
  • Modified Thioredoxin
    Publication number: 20080119398
    Abstract: ABSTRACT The present invention relates to a human modified thioredoxin composed of any of the following polypeptides:(a) a polypeptide modified by alteration or chemical modification of a cysteine residue at position 35 with another amino acid in an amino acid sequence of SEQ ID NO:2; and (b) a polypeptide having an amino acid sequence having one or more substituted, deleted, inserted or added amino acids in positions except for positions 32 and 35, preferably positions 32 to 35 in the amino acid sequence of SEQ ID NO:2, and having an apoptosis-inducing activity.
    Type: Application
    Filed: March 30, 2004
    Publication date: May 22, 2008
    Inventors: Yasuyuki Ishii, Junji Yodoi, Hajime Nakamura, Norihiko Kondo
  • Method and apparatus for lapping gear teeth while changing at least one of load torque, rotating speeds and rate of teeth contact point movement of the gears
    Patent number: 5191739
    Abstract: A method and an apparatus for lapping teeth of a pair of gears by rotating one of the gears in engagement with the other gear, while applying a load torque to the other gear and moving the gears relative to each other such that a teeth contact area of the gears is moved in a direction of width of contacting faces of the teeth of the gears, so that the face of each tooth of the gears is lapped over a substantially entire width thereof. A lapping controller is adapted to change at least one of the load torque applied to the relevent gear, rotating speeds of the gears, and a rate of movement of the teeth contact area of the gears, as the gears are moved relative to each other to move the teeth contact area of the gears in the direction of width of the contacting faces of the gears, so that the gear teeth are lapped efficiently, depending upon the configurations and conditions of use of the gears.
    Type: Grant
    Filed: December 5, 1990
    Date of Patent: March 9, 1993
    Assignee: Toyota Jidosha Kabushiki Kaisha
    Inventors: Norihiko Kondo, Mikio Tsuzuki, Yoshinori Miura