Patents by Inventor Norikazu Higashimura

Norikazu Higashimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for producing chiral hydroxyaldehyde compounds
    Patent number: 7402710
    Abstract: An industrial process for producing hydroxyaldehydes efficiently, by solving the problems of conventional DERA, such as low stability against aldehydes, low catalytic activity for aldol condensation, and the difficulty of controlling the number of acetaldehyde molecules to be condensed, is provided. According to the process, aldol condensation of a substituted or unsubstituted aliphatic aldehyde compound having 2 to 6 carbon atoms with acetaldehyde is conducted by using D-2-deoxyribose-5-phosphate aldolase which is highly stable against aldehydes and has high catalytic activity for aldol condensation, whereby a hydroxyaldehyde compound having the number of carbon atoms increased by two or four can be produced.
    Type: Grant
    Filed: March 28, 2005
    Date of Patent: July 22, 2008
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Kazuya Matsumoto, Yasushi Kazuno, Norikazu Higashimura, Toshihisa Ohshima, Haruhiko Sakuraba
  • Process For Producing Chiral Hydroxyaldehyde Compounds
    Publication number: 20070196906
    Abstract: An industrial process for producing hydroxyaldehydes efficiently, by solving the problems of conventional DERA, such as low stability against aldehydes, low catalytic activity for aldol condensation, and the difficulty of controlling the number of acetaldehyde molecules to be condensed, is provided. According to the process, aldol condensation of a substituted or unsubstituted aliphatic aldehyde compound having 2 to 6 carbon atoms with acetaldehyde is conducted by using D-2-deoxyribose-5-phosphate aldolase which is highly stable against aldehydes and has high catalytic activity for aldol condensation, whereby a hydroxyaldehyde compound having the number of carbon atoms increased by two or four can be produced.
    Type: Application
    Filed: March 28, 2005
    Publication date: August 23, 2007
    Applicant: Mitsui Chemicals, Inc.
    Inventors: Kazuya Matsumoto, Yasushi Kazuno, Norikazu Higashimura, Toshihisa Ohshima, Haruhiko Sakuraba
  • Process for producing a protein
    Publication number: 20020150979
    Abstract: An objective of this invention is to provide an effective process for producing a recombinant protein using E. coli and a technique therefor.
    Type: Application
    Filed: October 4, 2001
    Publication date: October 17, 2002
    Inventors: Naokazu Naitou, Kazuya Matsumoto, Norikazu Higashimura, Bunkichi Tsunekawa, Hiroshi Uchida, Mitsufumi Wada
  • Medicinal composition containing gp34 binding-inhibitor as the active ingredient
    Patent number: 6333035
    Abstract: The present invention relates to a pharmaceutical composition for the therapeutic treatment of autoimmune diseases including rheumatoid arthritis, multiple sclerosis, sarcoidosis, autoimmune uveitis, and inflammatory bowel disease, or graft-versus-host disease. The pharmaceutical composition contains, as the effective ingredient, a gp34 binding-inhibitory substance.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: December 25, 2001
    Assignee: Mitsui Chemicals, Inc.
    Inventors: Kazuo Sugamura, Kazuko Murata, Norikazu Higashimura