Patents by Inventor Noriko ITABA

Noriko ITABA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fibrosis-inhibiting composition, cells producing same, and cell sheet comprising said cells
    Patent number: 11866483
    Abstract: [Problem] To provide a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cells having fibrosis-inhibiting activity, which are useful in regenerative medicine. [Solution] A medium containing IC-2 or a related compound is inoculated with mesenchymal stem cells or bone marrow mononuclear cells, and the cells are cultured for a prescribed period of time while the IC-2 or related compound is maintained at a constant concentration, thereby allowing a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cultured cells having fibrosis-inhibiting activity, to be obtained.
    Type: Grant
    Filed: May 30, 2019
    Date of Patent: January 9, 2024
    Assignees: KanonCure, Inc., National University Corporation Tottori University
    Inventors: Yohei Kono, Noriko Itaba, Goshi Shiota
  • CELL SHEET HAVING FIBROSIS INHIBITORY ACTION
    Publication number: 20230117252
    Abstract: [Problem to be solved by the invention] To provide a cell sheet for increasing fibrosis inhibitory action, said cell sheet comprising bone marrow mononuclear cells, and a production method thereof. [Solution] A cell sheet comprising bone marrow mononuclear cells, said cell sheet being obtained by forming bone marrow mononuclear cells from a bone marrow mononuclear cell suspension into a sheet, and then shrinking and suspension culturing the result.
    Type: Application
    Filed: November 9, 2022
    Publication date: April 20, 2023
    Inventors: Goshi SHIOTA, Noriko ITABA, Yohei KONO
  • Inhibitory effect of low molecular weight compound on cancer and fibrosis
    Patent number: 11213527
    Abstract: A novel therapeutic drug for malignant tumors, cancer stem cells, or fibrosis is obtained. A therapeutic drug for malignant tumors or cancer stem cells is used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof. Alternatively, a therapeutic drug for fibrosis can be used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof.
    Type: Grant
    Filed: March 25, 2015
    Date of Patent: January 4, 2022
    Assignees: National University Corporation Tottori University, KanonCure, Inc.
    Inventors: Goshi Shiota, Noriko Itaba, Keita Kanki, Kenzo Seto, Hiroki Shimizu, Yohei Kouno, Shinya Kunita, Zyunya Adumi, Tomohiko Sakabe, Kenichiro Abe, Minoru Morimoto, Hiroyuki Oka
  • INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS
    Publication number: 20210386747
    Abstract: A novel therapeutic drug for malignant tumors, cancer stem cells, or fibrosis is obtained. A therapeutic drug for malignant tumors or cancer stem cells is used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof. Alternatively, a therapeutic drug for fibrosis can be used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof.
    Type: Application
    Filed: August 27, 2021
    Publication date: December 16, 2021
    Inventors: Goshi SHIOTA, Noriko ITABA, Keita KANKI, Kenzo SETO, Hiroki SHIMIZU, Yohei KOUNO, Shinya KUNITA, Zyunya ADUMI, Tomohiko SAKABE, Kenichiro ABE, Minoru MORIMOTO, Hiroyuki OKA
  • FIBROSIS-INHIBITING COMPOSITION, CELLS PRODUCING SAME, AND CELL SHEET COMPRISING SAID CELLS
    Publication number: 20210115112
    Abstract: [Problem] To provide a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cells having fibrosis-inhibiting activity, which are useful in regenerative medicine. [Solution] A medium containing IC-2 or a related compound is inoculated with mesenchymal stem cells or bone marrow mononuclear cells, and the cells are cultured for a prescribed period of time while the IC-2 or related compound is maintained at a constant concentration, thereby allowing a composition and a cell sheet which are highly effective for inhibiting fibrosis, or cultured cells having fibrosis-inhibiting activity, to be obtained.
    Type: Application
    Filed: May 30, 2019
    Publication date: April 22, 2021
    Inventors: Yohei KONO, Noriko ITABA, Goshi SHIOTA
  • CELL SHEET HAVING FIBROSIS INHIBITORY ACTION
    Publication number: 20200190476
    Abstract: [Problem to be solved by the invention] To provide a cell sheet for increasing fibrosis inhibitory action, said cell sheet comprising bone marrow mononuclear cells, and a production method thereof. [Solution] A cell sheet comprising bone marrow mononuclear cells, said cell sheet being obtained by forming bone marrow mononuclear cells from a bone marrow mononuclear cell suspension into a sheet, and then shrinking and suspension culturing the result.
    Type: Application
    Filed: August 27, 2018
    Publication date: June 18, 2020
    Inventors: Goshi SHIOTA, Noriko ITABA, Yohei KONO
  • Suppression and regeneration promoting effect of low molecular weight compound on cancer and fibrosis
    Patent number: 10597398
    Abstract: To obtain a novel therapeutic drug for a malignant tumor or fibrosis. Used is a compound represented by formula (1), a salt thereof, or a solvate thereof. Also used is a therapeutic drug for a malignant tumor or a therapeutic drug for fibrosis, comprising a compound represented by formula (1), a salt thereof, or a solvate thereof.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: March 24, 2020
    Assignees: National University Corporation Tottori University, KanonCure, Inc.
    Inventors: Goshi Shiota, Noriko Itaba, Minoru Morimoto, Hiroyuki Oka, Kenichiro Abe, Hiroki Shimizu, Yohei Kouno, Satoshi Yokogi
  • SUPPRESSION AND REGENERATION PROMOTING EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS
    Publication number: 20190055249
    Abstract: To obtain a novel therapeutic drug for a malignant tumor or fibrosis. Used is a compound represented by formula (1), a salt thereof, or a solvate thereof. Also used is a therapeutic drug for a malignant tumor or a therapeutic drug for fibrosis, comprising a compound represented by formula (1), a salt thereof, or a solvate thereof.
    Type: Application
    Filed: September 16, 2016
    Publication date: February 21, 2019
    Inventors: Goshi SHIOTA, Noriko ITABA, Minoru MORIMOTO, Hiroyuki OKA, Kenichiro ABE, Hiroki SHIMIZU, Yoohei KOUNO, Satoshi YOKOGI
  • INHIBITORY EFFECT OF LOW MOLECULAR WEIGHT COMPOUND ON CANCER AND FIBROSIS
    Publication number: 20180028536
    Abstract: A novel therapeutic drug for malignant tumors, cancer stem cells, or fibrosis is obtained. A therapeutic drug for malignant tumors or cancer stem cells is used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof. Alternatively, a therapeutic drug for fibrosis can be used that includes at least one compound selected from the group consisting of compounds represented by formulas (1), (2), and (5), a salt thereof, or a solvate thereof.
    Type: Application
    Filed: March 25, 2015
    Publication date: February 1, 2018
    Inventors: Goshi SHIOTA, Noriko ITABA, Keita KANKI, Kenzo SETO, Hiroki SHIMIZU, Yohei KOUNO, Shinya KUNITA, Zyunya ADUMI, Tomohiko SAKABE, Kenichiro ABE, Minoru MORIMOTO, Hiroyuki OKA