Patents by Inventor Noriko Tsutsumi

Noriko Tsutsumi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240101991
    Abstract: The present invention relates to polypeptides having trehalase activity, particularly derived from Talaromyces. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides for the production of ethanol.
    Type: Application
    Filed: September 28, 2022
    Publication date: March 28, 2024
    Applicant: NOVOZYMES A/S
    Inventors: Marc Dominique Morant, Tomoko Matsui, Kirk Matthew Schnorr, Shiro Fukuyama, Noriko Tsutsumi, Zhengfang Kang
  • Patent number: 11584783
    Abstract: The present invention relates to polypeptides having trehalase activity, particularly derived from Talaromyces. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides for the production of ethanol.
    Type: Grant
    Filed: June 26, 2018
    Date of Patent: February 21, 2023
    Assignee: NOVOZYMES A/S
    Inventors: Marc Dominique Morant, Tomoko Matsui, Kirk Matthew Schnorr, Shiro Fukuyama, Noriko Tsutsumi, Zhengfang Kang
  • Patent number: 11377648
    Abstract: The present invention relates to a hybrid polypeptide having alpha-amylase activity, selected from a first polypeptide sequence comprising a catalytic core, and a second polypeptide sequence comprising a carbohydrate binding module (CBM), wherein (a) the catalytic core is selected from a polypeptide having at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99% or 100% sequence identity to amino acids 20 to 494 of SEQ ID NO: 1 or amino acids 20 to 496 of SEQ ID NO: 1; and (b) the CBM is selected from a polypeptide having at least 75%, at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99% or 100% sequence identity to SEQ ID NO: 4, SEQ ID NO: 5, or SEQ ID NO: 6.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: July 5, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Tomoko Namoto, Takashi Nakanishi, Shiro Fukuyama, Noriko Tsutsumi, Keiichi Ayabe
  • Patent number: 11279921
    Abstract: The present invention relates to glucoamylase variants having an increase in raw starch activity compared to the guy-coamylase disclosed as SEQ ID NO: 2, comprising one or more modifications in the catalytic domain and/or one or more modifications in the starch binding domain selected from: a) at least one, preferably at least two, preferably at least three, preferably at least four of: V18M, T43K, N112L, T116R, A117Q, G120S, A271F, Y295W, Q318Y; and/or b) Introducing at least three, preferably at least four substitutions selected from the group: S458C, S458SCGG, S458SGGC, A493V, A518K, E520Q, N527M, S540K, R, S(G)546P, T(V)549W, N503R, N539R+I541Y+T543V+A545S+S546GCGV+G547S+S548T+T549A. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: April 10, 2018
    Date of Patent: March 22, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Tomoko Namoto, Noriko Tsutsumi, Keiichi Ayabe, Zhengfang Kang
  • Patent number: 11220679
    Abstract: The present invention relates to trehalase variants of the Myceliophthora sepedonium GH37 trehalase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: August 6, 2018
    Date of Patent: January 11, 2022
    Assignee: NOVOZYMES A/S
    Inventors: Noriko Tsutsumi, Tomoko Matsui, Yuma Kurakata
  • Publication number: 20210139875
    Abstract: The present invention relates to a hybrid polypeptide having alpha-amylase activity, selected from a first polypeptide sequence comprising a catalytic core, and a second polypeptide sequence comprising a carbohydrate binding module (CBM), wherein (a) the catalytic core is selected from a polypeptide having at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99% or 100% sequence identity to amino acids 20 to 494 of SEQ ID NO: 1 or amino acids 20 to 496 of SEQ ID NO: 1; and (b) the CBM is selected from a polypeptide having at least 75%, at least 80%, at least 85%, at least 90%, at least 91%, at least 92%, at least 93%, at least 94%, at least 95%, at least 96%, at least 97%, at least 98%, at least 99% or 100% sequence identity to SEQ ID NO: 4, SEQ ID NO: 5, or SEQ ID NO: 6.
    Type: Application
    Filed: April 8, 2019
    Publication date: May 13, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Tomoko Namoto, Takashi Nakanishi, Shiro Fukuyama, Noriko Tsutsumi, Keiichi Ayabe
  • Publication number: 20210087543
    Abstract: The present invention relates to trehalase variants of the Myceliophthora sepedonium GH37 trehalase. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: August 6, 2018
    Publication date: March 25, 2021
    Applicant: NOVOZYMES A/S
    Inventors: Noriko Tsutsumi, Tomoko Matsui, Yuma Kurakata
  • Publication number: 20200140495
    Abstract: The present invention relates to polypeptides having trehalase activity, particularly derived from Talaromyces. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides for the production of ethanol.
    Type: Application
    Filed: June 26, 2018
    Publication date: May 7, 2020
    Applicant: NOVOZYMES A/S
    Inventors: Marc Dominique Morant, Tomoko Matsui, Kirk Matthew Schnorr, Shiro Fukuyama, Noriko Tsutsumi, Zhengfang Kang
  • Publication number: 20200131491
    Abstract: The present invention relates to glucoamylase variants having an increase in raw starch activity compared to the guy-coamylase disclosed as SEQ ID NO: 2, comprising one or more modifications in the catalytic domain and/or one or more modifications in the starch binding domain selected from: a) at least one, preferably at least two, preferably at least three, preferably at least four of: V18M, T43K, N112L, T116R, A117Q, G120S, A271F, Y295W, Q318Y; and/or b) Introducing at least three, preferably at least four substitutions selected from the group: S458C, S458SCGG, S458SGGC, A493V, A518K, E520Q, N527M, S540K, R, S(G)546P, T(V)549W, N503R, N539R+I541Y+T543V+A545S+S546GCGV+G547S+S548T+T549A. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 10, 2018
    Publication date: April 30, 2020
    Applicant: NOVOZYMES A/S
    Inventors: Tomoko Namoto, Noriko Tsutsumi, Keiichi Ayabe, Zhengfang Kang
  • Patent number: 10584324
    Abstract: The present invention relates to glucoamylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: March 10, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Shiro Fukuyama, Noriko Tsutsumi, Keiichi Ayabe
  • Patent number: 10550374
    Abstract: The present invention relates to glucoamylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Grant
    Filed: April 29, 2014
    Date of Patent: February 4, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Noriko Tsutsumi, Keiichi Ayabe, Siik Kishishita
  • Patent number: 10538752
    Abstract: The present disclosure relates to isolated polypeptides having alpha-amylase activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing the polypeptides, and method of using polypeptides, including in ethanol production processes.
    Type: Grant
    Filed: August 17, 2017
    Date of Patent: January 21, 2020
    Assignee: NOVOZYMES A/S
    Inventors: Guillermo Coward-Kelly, Shiro Fukuyama, Noriko Tsutsumi, Keiichi Ayabe
  • Patent number: 9909112
    Abstract: The present invention relates to isolated polypeptides having alpha-amylase activity, catalytic domains, carbohydrate binding domains and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding domains.
    Type: Grant
    Filed: May 5, 2017
    Date of Patent: March 6, 2018
    Assignee: NOVOZYMES A/S
    Inventors: Ming Li, Junxin Duan, Noriko Tsutsumi, Guillermo Coward-Kelly, Henrik Lundkvist
  • Publication number: 20170349887
    Abstract: The present disclosure relates to isolated polypeptides having alpha-amylase activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing the polypeptides, and method of using polypeptides, including in ethanol production processes.
    Type: Application
    Filed: August 17, 2017
    Publication date: December 7, 2017
    Applicant: NOVOZYMES A/S
    Inventors: Guillermo Coward Kelly, Shiro Fukuyama, Noriko Tsutsumi, Keiichi Ayabe
  • Publication number: 20170306310
    Abstract: The present invention relates to glucoamylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: October 23, 2015
    Publication date: October 26, 2017
    Applicant: NOVOZYMES A/S
    Inventors: Shiro FUKUYAMA, Noriko TSUTSUMI, Keiichi AYABE
  • Patent number: 9765317
    Abstract: The present disclosure relates to isolated polypeptides having alpha-amylase activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing the polypeptides, and method of using polypeptides, including in ethanol production processes.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: September 19, 2017
    Assignee: NOVOZYMES A/S
    Inventors: Guillermo Coward Kelly, Shiro Fukuyama, Noriko Tsutsumi, Keiichi Ayabe
  • Publication number: 20170240873
    Abstract: The present invention relates to isolated polypeptides having alpha-amylase activity, catalytic domains, carbohydrate binding domains and polynucleotides encoding the polypeptides, catalytic domains or carbohydrate binding domains. The invention also relates to nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding domains.
    Type: Application
    Filed: May 5, 2017
    Publication date: August 24, 2017
    Applicant: NOVOZYMES A/S
    Inventors: Ming Li, Junxin Duan, Noriko Tsutsumi, Guillermo Coward-Kelly, Henrik Lundkvist
  • Publication number: 20160152960
    Abstract: The present invention relates to glucoamylase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.
    Type: Application
    Filed: April 29, 2014
    Publication date: June 2, 2016
    Applicant: NOVOZYMES A/S
    Inventors: Noriko Tsutsumi, Keiichi Ayabe, Siik Kishishita
  • Publication number: 20150337277
    Abstract: The present disclosure relates to isolated polypeptides having alpha-amylase activity, polynucleotides encoding the polypeptides, nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing the polypeptides, and method of using polypeptides, including in ethanol production processes.
    Type: Application
    Filed: December 13, 2013
    Publication date: November 26, 2015
    Inventors: Guillermo Coward Kelly, Shiro Fukuyama, Noriko Tsutsumi, Keiichi Ayabe
  • Publication number: 20150031091
    Abstract: The present invention provides isolated polypeptides having alpha-amylase activity catalytic domains, carbohydrate binding domains and polynucleotide encoding the polypeptides, catalytic domains or carbohydrate binding domains. The invention also provides nucleic acid constructs, vectors, and host cells comprising the polynucleotides as well as methods of producing and using the polypeptides, catalytic domains or carbohydrate binding domains.
    Type: Application
    Filed: September 29, 2012
    Publication date: January 29, 2015
    Applicant: NOVOZYMES A/S
    Inventors: Ming Li, Junxin Duan, Noriko Tsutsumi, Guillermo Coward-Kelly, Henrik Lundkvist