Patents by Inventor Norimitsu Hariguchi
Norimitsu Hariguchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10851079Abstract: The purpose of the present invention is to provide a compound having excellent antibacterial activity against mycobacterium tuberculosis, multidrug-resistant tuberculosis bacteria, and/or non-tuberculous acid-fast bacteria. A compound represented by formula [I]: (in the formula, each symbol is as described in the attached specification), or a salt thereof can be used to diagnose, prevent, and/or treat tuberculosis.Type: GrantFiled: February 27, 2017Date of Patent: December 1, 2020Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Yoshikazu Kawano, Hiroshi Shimizu, Shunpei Ishikawa, Isao Takemura, Norimitsu Hariguchi, Miki Matsuba, Makoto Matsumoto
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Patent number: 10464926Abstract: It is an object of the present invention to provide a compound having an excellent antibacterial activity against tuberculosis bacteria, multidrug-resistant tuberculosis bacteria and/or non-tuberculous mycobacteria. Disclosed is a compound of the general formula (1): wherein each symbol is defined as described in the attached specification, or a salt thereof.Type: GrantFiled: July 9, 2018Date of Patent: November 5, 2019Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hiroshi Shimizu, Yoshikazu Kawano, Shunpei Ishikawa, Yukitaka Uematsu, Toshio Shinohara, Motohiro Itotani, Yoshikazu Haraguchi, Isao Takemura, Atsunori Kaneshige, Yuya Nakai, Norimitsu Hariguchi, Yohei Hayashi, Makoto Matsumoto
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Publication number: 20190040039Abstract: The purpose of the present invention is to provide a compound having excellent antibacterial activity against mycobacterium tuberculosis, multidrug-resistant tuberculosis bacteria, and/or non-tuberculous acid-fast bacteria. A compound represented by formula [I]: (in the formula, each symbol is as described in the attached specification), or a salt thereof can be used to diagnose, prevent, and/or treat tuberculosis.Type: ApplicationFiled: February 27, 2017Publication date: February 7, 2019Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Yoshikazu KAWANO, Hiroshi SHIMIZU, Shunpei ISHIKAWA, Isso TAKEMURA, Norimitsu HARIGUCHI, Miki MATSUBA, Makoto MATSUMOTO
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Publication number: 20180312488Abstract: It is an object of the present invention to provide a compound having an excellent antibacterial activity against tuberculosis bacteria, multidrug-resistant tuberculosis bacteria and/or non-tuberculous mycobacteria. Disclosed is a compound of the general formula (1): wherein each symbol is defined as described in the attached specification, or a salt thereof.Type: ApplicationFiled: July 9, 2018Publication date: November 1, 2018Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hiroshi SHIMIZU, Yoshikazu KAWANO, Shunpei ISHIKAWA, Yukitaka UEMATSU, Toshio SHINOHARA, Motohiro ITOTANI, Yoshikazu HARAGUCHI, Isao TAKEMURA, Atsunori KANESHIGE, Yuya NAKAI, Norimitsu HARIGUCHI, Yohei HAYASHI, Makoto MATSUMOTO
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Patent number: 10053446Abstract: It is an object of the present invention to provide a compound having an excellent antibacterial activity against tuberculosis bacteria, multidrug-resistant tuberculosis bacteria and/or non-tuberculous mycobacteria. Disclosed is a compound of the general formula (1): wherein each symbol is defined as described in the attached specification, or a salt thereof.Type: GrantFiled: August 28, 2015Date of Patent: August 21, 2018Assignee: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hiroshi Shimizu, Yoshikazu Kawano, Shunpei Ishikawa, Yukitaka Uematsu, Toshio Shinohara, Motohiro Itotani, Yoshikazu Haraguchi, Isao Takemura, Atsunori Kaneshige, Yuya Nakai, Norimitsu Hariguchi, Yohei Hayashi, Makoto Matsumoto
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Publication number: 20170253576Abstract: It is an object of the present invention to provide a compound having an excellent antibacterial activity against tuberculosis bacteria, multidrug-resistant tuberculosis bacteria and/or non-tuberculous mycobacteria. Disclosed is a compound of the general formula (1): wherein each symbol is defined as described in the attached specification, or a salt thereof.Type: ApplicationFiled: August 28, 2015Publication date: September 7, 2017Applicant: OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Hiroshi SHIMIZU, Yoshikazu KAWANO, Shunpei ISHIKAWA, Yukitaka UEMATSU, Toshio SHINOHARA, Motohiro ITOTANI, Yoshikazu HARAGUCHI, Isao TAKEMURA, Atsunori KANESHIGE, Yuya NAKAI, Norimitsu HARIGUCHI, Yohei HAYASHI, Makoto MATSUMOTO
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Patent number: 9333249Abstract: The present invention provides a novel transfer vector and a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient, which are useful as preventive or therapeutic drugs for infectious diseases such as malaria and influenza; and methods for preventing and treating infectious diseases such as malaria and influenza. More specifically, the invention provides a recombinant transfer vector capable of expressing a foreign gene fused to a virus gene under the control of a dual promoter; a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient; and methods for preventing and treating infectious diseases such as malaria and influenza comprising administrating the recombinant baculovirus to patients.Type: GrantFiled: August 15, 2008Date of Patent: May 10, 2016Assignees: EDUCATIONAL FOUNDATION JICHI MEDICAL UNIVERSITY, OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Shigeto Yoshida, Masanori Kawasaki, Makoto Matsumoto, Yoshio Ohba, Masahiro Saito, Yoshihiro Goto, Katsuya Inagaki, Masami Mizukoshi, Norimitsu Hariguchi, Kuniko Hirota
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Patent number: 9327018Abstract: The present invention provides a novel transfer vector and a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient, which are useful as preventive or therapeutic drugs for infectious diseases such as malaria and influenza; and methods for preventing and treating infectious diseases such as malaria and influenza. More specifically, the invention provides a recombinant transfer vector capable of expressing a foreign gene fused to a virus gene under the control of a dual promoter; a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient; and methods for preventing and treating infectious diseases such as malaria and influenza comprising administrating the recombinant baculovirus to patients.Type: GrantFiled: September 14, 2012Date of Patent: May 3, 2016Assignees: EDUCATIONAL FOUNDATION JICHI MEDICAL UNIVERSITY, OTSUKA PHARMACEUTICAL CO., LTD.Inventors: Shigeto Yoshida, Masanori Kawasaki, Makoto Matsumoto, Yoshio Ohba, Masahiro Saito, Yoshihiro Goto, Katsuya Inagaki, Masami Mizukoshi, Norimitsu Hariguchi, Kuniko Hirota
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Patent number: 9023365Abstract: A recombinant transfer vector capable of expressing a foreign gene fused to a viral gene under the control of dual promoters and a recombinant baculovirus, and methods for production thereof, as well as pharmaceuticals comprising the recombinant baculovirus as an active ingredient.Type: GrantFiled: February 8, 2007Date of Patent: May 5, 2015Assignees: Educational Foundation Jichi Medical University, Otsuka Pharmaceutical Co., Ltd.Inventors: Shigeto Yoshida, Yoshio Ohba, Norimitsu Hariguchi, Masami Mizukoshi, Masanori Kawasaki, Makoto Matsumoto, Yoshihiro Goto
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Publication number: 20130022637Abstract: The present invention provides a novel transfer vector and a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient, which are useful as preventive or therapeutic drugs for infectious diseases such as malaria and influenza; and methods for preventing and treating infectious diseases such as malaria and influenza. More specifically, the invention provides a recombinant transfer vector capable of expressing a foreign gene fused to a virus gene under the control of a dual promoter; a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient; and methods for preventing and treating infectious diseases such as malaria and influenza comprising administrating the recombinant baculovirus to patients.Type: ApplicationFiled: September 14, 2012Publication date: January 24, 2013Applicants: OTSUKA PHARMACEUTICAL CO., LTD., EDUCATIONAL FOUNDATION JICHI MEDICAL UNIVERSITYInventors: Shigeto YOSHIDA, Masanori KAWASAKI, Makoto MATSUMOTO, Yoshio OHBA, Masahiro SAITO, Yoshihiro GOTO, Katsuya INAGAKI, Masami MIZUKOSHI, Norimitsu HARIGUCHI, Kuniko HIROTA
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Publication number: 20100233202Abstract: A recombinant transfer vector capable of expressing a foreign gene fused to a viral gene under the control of dual promoters and a recombinant baculovirus, and methods for production thereof, as well as pharmaceuticals comprising the recombinant baculovirus as an active ingredient.Type: ApplicationFiled: February 8, 2007Publication date: September 16, 2010Inventors: Shigeto Yoshida, Yoshio Ohba, Norimitsu Hariguchi, Masami Mizukoshi, Masanori Kawasaki, Makoto Matsumoto, Yoshihiro Goto
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Publication number: 20090324702Abstract: The present invention provides a novel transfer vector and a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient, which are useful as preventive or therapeutic drugs for infectious diseases such as malaria and influenza; and methods for preventing and treating infectious diseases such as malaria and influenza. More specifically, the invention provides a recombinant transfer vector capable of expressing a foreign gene fused to a virus gene under the control of a dual promoter; a recombinant baculovirus; methods for the production thereof; pharmaceuticals containing the recombinant baculovirus as an active ingredient; and methods for preventing and treating infectious diseases such as malaria and influenza comprising administrating the recombinant baculovirus to patients.Type: ApplicationFiled: August 15, 2008Publication date: December 31, 2009Inventors: Shigeto Yoshida, Masanori Kawasaki, Makoto Matsumoto, Yoshio Ohba, Masahiro Saito, Yoshihiro Goto, Katsuya Inagaki, Masami Mizukoshi, Norimitsu Hariguchi, Kuniko Hirota