Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.

Abstract: An interchangeable lens has a lens frame holding a movable lens group, another lens frame holding another movable lens group, one actuator that drives one lens frame, and the other actuator that drives the other lens frame. A first yoke forming a magnetic circuit of the one actuator and a second yoke forming a magnetic circuit of the other actuator are disposed away from each other in an optical axis direction, and a nonmagnetic member is interposed between the first yoke and the second yoke.

Abstract: An interchangeable lens has a lens frame holding a movable lens group, another lens frame holding another movable lens group, one actuator that drives one lens frame, and the other actuator that drives the other lens frame. A first yoke forming a magnetic circuit of the one actuator and a second yoke forming a magnetic circuit of the other actuator are disposed away from each other in an optical axis direction, and a nonmagnetic member is interposed between the first yoke and the second yoke.

Abstract: Disclosed is a method for inscribing or marking surfaces (1), especially metal surfaces. In said method, the surface (1) that is to be inscribed or marked is coated with an absorption promoter (2) in a first step, whereupon a high-energy beam (4), e.g. a laser beam, which colors the surface (1) as a result of the interaction with the absorption promoter by means of a temperature increase, is applied to surface elements that re to be inscribed or colored.

Abstract: A communication device includes a current information storage unit 130 that stores the bit boundary signal at each of timings at which a sampling clock is updated, a past information storage unit 140 that takes in and stores a signal stored in the current information storage unit 130 when a variation point of a reception signal is detected, and does not update a signal stored therein when no variation point of the reception signal is detected, and a clock selection unit 44 that selects CLKSEL2 used for the sampling of the reception signal from N-phase clocks based on a signal stored in the current information storage unit 130 when a variation point of the reception signal is detected, and selects CLKSEL3 based on a signal stored in the past information storage unit 140 when no variation point of the reception signal is detected.

Abstract: A communication apparatus including a clock generation circuit outputting a plurality of clocks, each clock having a different phase from the other, a synchronization detection block receiving a sync word and a payload having a predetermined length after receiving the payload, sampling the sync word by using each of the plurality of clocks and to output a first signal indicating a clock or clocks capable of sampling the sync word successfully, the synchronization detection block being capable of sampling the payload by using a clock or clocks, a clock phase selection block coupled to the synchronization detection block to receive the first signal, and a clock gate unit to receive each of the plurality of clocks and the second signal to output the selected one of the plurality of clocks, and not to output a rest of the plurality of the clocks based on the second signal.

Abstract: A communication apparatus including a first unit which performs sampling of a synchronization pattern included in a signal with multiple clocks having different phases and identifies clocks where a predetermined synchronization pattern could be correctly sampled, from among the multiple clocks; a second unit which identifies, from among the multiple clocks, a first and second clock having a first clock edge which is nearest to the time point at which the data of the synchronization pattern changes and a second clock edge which is second nearest to the time point next to the first clock edge, respectively, the first and second clock edges being where the sampling of the synchronization pattern is performed; and a judgment section which judges one of clocks other than the first and second clocks, among the clocks with which the predetermined synchronization pattern was correctly sampled, to be used for sampling of the signal.

Abstract: There is provided a communication apparatus capable of reducing power consumption. The communication apparatus in accordance with the present invention includes a synchronization detection block 30 which detects synchronization by performing a receiving process using a plurality of clocks whose phase differs from each other with respect to synchronization information contained in a first frame as well as identifies the synchronization detected clocks as candidate clocks to be selected; a clock phase selection block 40 which selects a sampling clock to be used for sampling of the transmission signal from the candidate clocks to be selected, selects a stop clock separated by a predetermined phase from the selected sampling clock, and outputs an instruction for the stop clock; and a clock gate unit 60 which, terminates supplying the stop clock from the plurality of clocks to the synchronization detection block 30 as well as supplies other clocks to the synchronization detection block 30.

Abstract: A communication device includes a current information storage unit 130 that stores the bit boundary signal at each of timings at which a sampling clock is updated, a past information storage unit 140 that takes in and stores a signal stored in the current information storage unit 130 when a variation point of a reception signal is detected, and does not update a signal stored therein when no variation point of the reception signal is detected, and a clock selection unit 44 that selects CLKSEL2 used for the sampling of the reception signal from N-phase clocks based on a signal stored in the current information storage unit 130 when a variation point of the reception signal is detected, and selects CLKSEL3 based on a signal stored in the past information storage unit 140 when no variation point of the reception signal is detected.

Abstract: A semiconductor integrated circuit includes an oscillation circuit for generating multiple clocks of mutually different phases, and is also characterized in selecting a single clock FCLK_P from among multiple clocks FCLK_P [n-1:0] for use in transmitting IQ Serial transmission signals and, utilizing the FCLK_P to transmit an IQ Serial transmission signal.

Abstract: Disclosed is a method for inscribing or marking surfaces (1), especially metal surfaces. In said method, the surface (1) that is to be inscribed or marked is coated with an absorption promoter (2) in a first step, whereupon a high-energy beam (4), e.g. a laser beam, which colors the surface (1) as a result of the interaction with the absorption promoter by means of a temperature increase, is applied to surface elements that re to be inscribed or colored.

Abstract: A communication apparatus which includes a clock generation circuit outputting a plurality of clocks, each of said plurality of clocks having a different phase from each other; a synchronization detection block receiving a sync word and a payload having a predetermined length after receiving said payload, sampling said sync word by using each of said plurality of clocks and to output a first signal indicating a clock or clocks capable of sampling said sync word successfully, said synchronization detection block being capable of sampling said payload by using a clock or clocks inputted thereinto; a clock phase selection block coupled to said synchronization detection block to-receive said first signal to select one of said plurality of clocks in accordance with said first signal and to output a second signal indicating a selected clock; and a clock gate unit coupled between said clock generation circuit and said synchronization detection block and coupled to said clock phase selection block to receive each of

Abstract: There is provided a communication apparatus capable of reducing power consumption. The communication apparatus in accordance with the present invention includes a synchronization detection block 30 which detects synchronization by performing a receiving process using a plurality of clocks whose phase differs from each other with respect to synchronization information contained in a first frame as well as identifies the synchronization detected clocks as candidate clocks to be selected; a clock phase selection block 40 which selects a sampling clock to be used for sampling of the transmission signal from the candidate clocks to be selected, selects a stop clock separated by a predetermined phase from the selected sampling clock, and outputs an instruction for the stop clock; and a clock gate unit 60 which, terminates supplying the stop clock from the plurality of clocks to the synchronization detection block 30 as well as supplies other clocks to the synchronization detection block 30.

Abstract: A conventional apparatus has a problem that delay occurs in selection of the phase of a synchronization clock.

Abstract: The present invention provides a high-efficiency absorption refrigerating machine which can recover heat from a heat source and can efficiently recover heat from an internal cycle. The absorption refrigerating machine includes an evaporator, an absorber (A), a condenser (C), a high-temperature regenerator (GH), a low-temperature regenerator (GL), a low-temperature solution heat exchanger (LX), and solution paths and refrigerant paths by which these units are connected. The absorption refrigerating machine further comprises two branch solution paths branched from a solution supply path through which a dilute solution is introduced from the absorption (A) to the high-temperature regenerator (GH). On one of the branch solution paths, there is disposed a drain heat exchanger (DX) operable to perform heat exchange between the dilute solution in the branch solution path and an exhaust heat source which has heated the high-temperature regenerator (GH).

Abstract: The present invention provides a high-efficiency absorption refrigerating machine which can recover heat from a heat source and can efficiently recover heat from an internal cycle. The absorption refrigerating machine includes an evaporator, an absorber (A), a condenser (C), a high-temperature regenerator (GH), a low-temperature regenerator (GL), a low-temperature solution heat exchanger (LX), and solution paths and refrigerant paths by which these units are connected. The absorption refrigerating machine further comprises two branch solution paths branched from a solution supply path through which a dilute solution is introduced from the absorption (A) to the high-temperature regenerator (GH). On one of the branch solution paths, there is disposed a drain heat exchanger (DX) operable to perform heat exchange between the dilute solution in the branch solution path and an exhaust heat source which has heated the high-temperature regenerator (GH).

Abstract: A cosmetic material sheet which comprises a sheet substrate 1 having, on an upper surface thereof, a large number of concave portions 5 arranged in a checkered pattern, a foundation layer 6 provided at a given position on the upper surface of the sheet substrate 1 in a state of covering arbitrary concave portions 5 out of a large number of concave portions 5, and a protective cover 3 attached releaseably on the upper surface of the sheet substrate 1 in a state of covering the foundation layer 6, wherein each concave portion 5 has an oblong shape in a plan view and has a bottom part thereof formed into a curved plane of a dish shape.

Abstract: A method of measuring a temperature of an object body in an electric furnace, based on an intensity of a radiant energy emitted from the object body, the electric furnace being provided with an electric heater operable by application of a drive voltage thereto to heat the object body, the method comprising: a radiant-energy detecting step of detecting an intensity of a radiant energy emitted from the object body; a stray-light noise eliminating step of determining as a noise an intensity of a radiant energy of a stray light which is emitted from an inner wall surface of the electric furnace toward the object body and reflected by a surface of the object body, according to a predetermined relationship between the intensity of the radiant energy of the stray light and the drive voltage applied to the electric heater and based on an actually applied value of the drive voltage, and subtracting the intensity of the radiant energy of the stray light determined as the noise, from the detected intensity of the radian

Abstract: Method and apparatus for measuring a surface temperature of an object body, by calculating a temperature at each picture element of an image of the object body, on the basis of a radiant intensity ratio at each pair of corresponding picture elements of a first and a second image which are obtained with respective radiations having respective first and second wavelengths which are selected from a light emitted from the surface of the body, by a first filter which permits transmission therethrough a radiation having the first wavelength which is selected according to a radiant intensity curve corresponding to a wavelength of a black body at a lower limit of a temperature measurement range, and which is within a high radiant intensity range in which the radiant intensity is higher than a radiant intensity at a normal room temperature, and a second filter which permits transmission therethrough a radiation having the second wavelength which is selected within the high radiant intensity range, such that the second

Abstract: Method and apparatus for measuring a surface temperature of an object body, by calculating a temperature at each picture element of an image of the object body, on the basis of a radiant intensity ratio at each pair of corresponding picture elements of a first and a second image which are obtained with respective radiations having respective first and second wavelengths which are selected from a light emitted from the surface of the body, by a first filter which permits transmission therethrough a radiation having the first wavelength which is selected according to a radiant-intensity curve corresponding to a wavelength of a black body at a lower limit of a temperature measurement range, and which is within a high radiant-intensity range in which the radiant intensity is higher than a radiant intensity at a normal room temperature, and a second filter which permits transmission therethrough a radiation having the second wavelength which is selected within the high radiant-intensity range, such that the second