Patents by Inventor Norio Sakuragawa

Norio Sakuragawa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HUMAN STEM CELLS ORIGINATING FROM HUMAN AMNIOTIC MESENCHYMAL CELL LAYER
    Publication number: 20100330672
    Abstract: Neural stem cells which can be provided stably and which are free from the problem of compatibility in transplantation are disclosed. The stem cells are separated from human amniotic mesenchymal cell layer and express vimentin, nestin and BrdU which are markers of neural stem cells. The stem cells can also be differentiated to cells expressing alkaline phosphatase, that is, osteocytes, and to cells expressing collagen type II, that is, chondrocytes.
    Type: Application
    Filed: September 10, 2010
    Publication date: December 30, 2010
    Inventors: Norio SAKURAGAWA, Saiko Uchida
  • Human Bone Stem Cells From Amniotic Mesenchymal Cell Layer
    Publication number: 20100254954
    Abstract: A bone stem cell which may be supplied stably and which is free from the problem about the compatibility in transplantation is disclosed. The bone stem cell according to the present invention is separated from human amniotic mesenchymal cell layer. The bone stem cell may be used for osteogenesis in a bone defect or the like.
    Type: Application
    Filed: June 16, 2010
    Publication date: October 7, 2010
    Inventors: Norio SAKURAGAWA, Saiko Uchida
  • SIDE POPULATION CELLS ORIGINATED FROM HUMAN AMNION AND THEIR USES
    Publication number: 20100015712
    Abstract: Cells which may be differentiated at least into nerve cells, which are useful for therapies of brain metabolic diseases, are disclosed. The cells are side population cell separated from human amniotic mesenchymal cell layer, in which expressions of Oct-4 gene, Sox-2 gene and Rex-1 gene are observed by RT-PCR, and which are vimentin-positive and CK19-positive in immunocytostaining.
    Type: Application
    Filed: July 8, 2009
    Publication date: January 21, 2010
    Inventors: Norio SAKURAGAWA, Yasunobu Yokoyama
  • Human stem cells originating from human amniotic mesenchymal cell layer
    Publication number: 20060281178
    Abstract: Neural stem cells which can be provided stably and which are free from the problem of compatibility in transplantation are disclosed. The stem cells are separated from human amniotic mesenchymal cell layer and express vimentin, nestin and BrdU which are markers of neural stem cells. The stem cells can also be differentiated to cells expressing alkaline phosphatase, that is, osteocytes, and to cells expressing collagen type II, that is, chondrocytes.
    Type: Application
    Filed: August 25, 2006
    Publication date: December 14, 2006
    Inventors: Norio Sakuragawa, Saiko Uchida
  • Human bone stem cells
    Publication number: 20060147424
    Abstract: A bone stem cell which may be supplied stably and which is free from the problem about the compatibility in transplantation is disclosed. The bone stem cell according to the present invention is separated from human amniotic mesenchymal cell layer. The bone stem cell may be used for osteogenesis in a bone defect or the like.
    Type: Application
    Filed: August 21, 2003
    Publication date: July 6, 2006
    Applicant: NORIO SAKURAGAWA
    Inventors: Norio Sakuragawa, Saiko Uchida
  • Side population cells originated from human amnion and their uses
    Publication number: 20050089513
    Abstract: Cells which may be differentiated at least into nerve cells, which are useful for therapies of brain metabolic diseases, are disclosed. The cells are side population cell separated from human amniotic mesenchymal cell layer, in which expressions of Oct-4 gene, Sox-2 gene and Rex-1 gene are observed by RT-PCR, and which are vimentin-positive and CK19-positive in immunocytostaining.
    Type: Application
    Filed: August 17, 2004
    Publication date: April 28, 2005
    Applicants: Norio SAKURAGAWA, SRL, INC.
    Inventors: Norio Sakuragawa, Yasunobu Yokoyama
  • Human stem cells originated from human amniotic mesenchymal cell layer
    Publication number: 20030044977
    Abstract: Neural stem cells which can be provided stably and which are free from the problem of compatibility in transplantation are disclosed. The stem cells are separated from human amniotic mesenchymal cell layer and express vimentin, nestin and BrdU which are markers of neural stem cells. The stem cells can also be differentiated to cells expressing alkaline phosphatase, that is, osteocytes, and to cells expressing collagen type II, that is, chondrocytes.
    Type: Application
    Filed: July 30, 2002
    Publication date: March 6, 2003
    Inventors: Norio Sakuragawa, Saiko Uchida
  • Transfected human amniotic cells and method for producing a gene product
    Patent number: 6117676
    Abstract: The present invention provides a human amniotic cell in which a gene desired to be expressed is introduced, and wherein said human amniotic cell expresses the product encoded by said gene. The present invention also provides a method for treating hereditary diseases comprising transplanting the human amniotic cells.
    Type: Grant
    Filed: April 30, 1996
    Date of Patent: September 12, 2000
    Assignee: Srl, Inc.
    Inventor: Norio Sakuragawa