Patents by Inventor Noritada Kaji
Noritada Kaji has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11169071Abstract: In a method for analyzing samples involving the use of a device for analyzing samples, the device for analyzing samples includes at least a movement part through which a sample moves, and a measurement unit that is formed in a middle of the movement part and that measures a value of an ion current when the sample passes through the movement part. The analysis method includes at least a measurement step for measuring the value of the ion current when the sample passes through the movement part, and a determination step for determining a change over time in a quantity of ions from the value of the ion current measured in the measurement step. The quantity of ions includes a quantity of ions that have leaked from the sample during movement of the sample through the movement part.Type: GrantFiled: October 4, 2017Date of Patent: November 9, 2021Assignees: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY, OSAKA UNIVERSITY, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Hirotoshi Yasaki, Takao Yasui, Noritada Kaji, Yoshinobu Baba, Tomoji Kawai, Satoyuki Kawano, Kentaro Doi, Takeshi Yanagida, Mao Fukuyama
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Patent number: 10877021Abstract: A device for biological material detection includes a substrate; a through-hole through which a biological material to be tested passes, the through-hole being formed in the substrate; a molecule that interacts with the biological material to be tested passing through, the molecule being formed in the through-hole; a first chamber member that forms, with at least the surface including the through-hole on one surface side of the substrate, a first chamber to be filled with electrolyte; and a second chamber member that forms, with at least the surface including the through-hole on the other surface side of the substrate, a second chamber to be filled with electrolyte. The biological material to be tested is identified by the waveform of the ion current (passage time, shape, etc.) when the biological material to be tested passes through the through-hole.Type: GrantFiled: April 21, 2017Date of Patent: December 29, 2020Assignees: OSAKA UNIVERSITY, TOKYO INSTITUTE OF TECHNOLOGY, NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITYInventors: Makusu Tsutsui, Kazumichi Yokota, Masateru Taniguchi, Tomoji Kawai, Mina Okochi, Masayoshi Tanaka, Yoshinobu Baba, Noritada Kaji, Takao Yasui, Yuji Miyahara, Yukichi Horiguchi
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Patent number: 10830685Abstract: Provided is a device for electrical measurement designed to be able to perform high sensitivity detection by reading not only changes in steady-state current, but also the occurrence of transient current, and an electrical measurement apparatus including the device for electrical measurement. The device for electrical measurement includes a substrate on which are formed at least a sample separation channel and a sample migration channel, as well as a sample measuring unit, with one end of the sample separation channel formed to connect to one end of the sample migration channel, and the sample measuring unit including a first measuring unit connected to the sample migration channel, and a second measuring unit connected to the sample migration channel from the reverse side to the first measuring unit.Type: GrantFiled: April 6, 2016Date of Patent: November 10, 2020Assignee: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITYInventors: Yoshinobu Baba, Noritada Kaji, Takao Yasui, Tomoji Kawai, Takeshi Yanagida
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Publication number: 20200033248Abstract: In a method for analyzing samples involving the use of a device for analyzing samples, the device for analyzing samples includes at least a movement part through which a sample moves, and a measurement unit that is formed in a middle of the movement part and that measures a value of an ion current when the sample passes through the movement part. The analysis method includes at least a measurement step for measuring the value of the ion current when the sample passes through the movement part, and a determination step for determining a change over time in a quantity of ions from the value of the ion current measured in the measurement step. The quantity of ions includes a quantity of ions that have leaked from the sample during movement of the sample through the movement part.Type: ApplicationFiled: October 4, 2017Publication date: January 30, 2020Inventors: Hirotoshi YASAKI, Takao YASUI, Noritada KAJI, Yoshinobu BABA, Tomoji KAWAI, Satoyuki KAWANO, Kentaro DOI, Takeshi YANAGIDA, Mao FUKUYAMA
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Publication number: 20190128888Abstract: A device for biological material detection includes a substrate; a through-hole through which a biological material to be tested passes, the through-hole being formed in the substrate; a molecule that interacts with the biological material to be tested passing through, the molecule being formed in the through-hole; a first chamber member that forms, with at least the surface including the through-hole on one surface side of the substrate, a first chamber to be filled with electrolyte; and a second chamber member that forms, with at least the surface including the through-hole on the other surface side of the substrate, a second chamber to be filled with electrolyte. The biological material to be tested is identified by the waveform of the ion current (passage time, shape, etc.) when the biological material to be tested passes through the through-hole.Type: ApplicationFiled: April 21, 2017Publication date: May 2, 2019Inventors: Makusu TSUTSUI, Kazumichi YOKOTA, Masateru TANIGUCHI, Tomoji KAWAI, Mina OKOCHI, Masayoshi TANAKA, Yoshinobu BABA, Noritada KAJI, Takao YASUI, Yuji MIYAHARA, Yukichi HORIGUCHI
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Publication number: 20180100792Abstract: Provided is a device for electrical measurement designed to be able to perform high sensitivity detection by reading not only changes in steady-state current, but also the occurrence of transient current, and an electrical measurement apparatus including the device for electrical measurement. The device for electrical measurement includes a substrate on which are formed at least a sample separation channel and a sample migration channel, as well as a sample measuring unit, with one end of the sample separation channel formed to connect to one end of the sample migration channel, and the sample measuring unit including a first measuring unit connected to the sample migration channel, and a second measuring unit connected to the sample migration channel from the reverse side to the first measuring unit.Type: ApplicationFiled: April 6, 2016Publication date: April 12, 2018Inventors: Yoshinobu BABA, Noritada KAJI, Takao YASUI, Tomoji KAWAI, Takeshi YANAGIDA
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Patent number: 8920845Abstract: It is intended to provide a method whereby various kinds of microcapsules, which are usable in, for example, a gene vector, can be produced in a small amount. This production method comprises: feeding a fluid containing a substance to be encapsulated into at lease one (13) of material-feeding microchannels in a substrate in which these material-feeding microchannels (12, 13, 14) and a reaction microchannel (18) connected to these material-feeding microchannels are formed; feeding an envelop-forming fluid containing a material for forming envelopes into at least one of the other material-feeding microchannels (12, 14); and allowing the envelope-forming fluid and the fluid containing the encapsulated substance that converge in the reaction microchannel from each material-feeding microchannel to flow through the reaction microchannel while continuously maintaining the interface between the fluids formed at the confluence thereof.Type: GrantFiled: November 2, 2007Date of Patent: December 30, 2014Assignee: National University Corporation Nagoya UniversityInventors: Yoshinobu Baba, Manabu Tokeshi, Noritada Kaji, Hideyoshi Harashima, Kentaro Kogure, Yasuo Shinohara, Hiroshi Kuramoto
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Patent number: 8420891Abstract: Disclosed is a method for introducing a foreign substance (3) into a cell (1) having a cell wall. The method comprises the steps of: providing a carbon nanotube (2) carrying at least one enzyme capable of decomposing a cell wall; supplying the carbon nanotube (2) and the foreign substance (3) into a treatment solution containing the cell (1); decomposing the cell wall of the cell (1) by the action of the enzyme carried on the carbon nanotube (2) upon the contact of the carbon nanotube (2) with the cell (1); and introducing the foreign substance (3) into the cell (1) through a site decomposed with the enzyme on the cell wall.Type: GrantFiled: June 11, 2008Date of Patent: April 16, 2013Assignee: National University Corporation Nagoya UniversityInventors: Yoshinobu Baba, Manabu Tokeshi, Noritada Kaji, Ibrahim Maged Fouad Serag Eldin Bayoumi
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Publication number: 20100248373Abstract: Disclosed is a method for introducing a foreign substance (3) into a cell (1) having a cell wall. The method comprises the steps of: providing a carbon nanotube (2) carrying at least one enzyme capable of decomposing a cell wall; supplying the carbon nanotube (2) and the foreign substance (3) into a treatment solution containing the cell (1); decomposing the cell wall of the cell (1) by the action of the enzyme carried on the carbon nanotube (2) upon the contact of the carbon nanotube (2) with the cell (1); and introducing the foreign substance (3) into the cell (1) through a site decomposed with the enzyme on the cell wall.Type: ApplicationFiled: June 11, 2008Publication date: September 30, 2010Applicant: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITYInventors: Yoshinobu Baba, Manabu Tokeshi, Noritada Kaji, Ibrahim Maged Fouad Serag Eldin Bayoumi
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Publication number: 20100143482Abstract: It is intended to provide a method whereby various kinds of microcapsules, which are usable in, for example, a gene vector, can be produced in a small amount. This production method comprises: feeding a fluid containing a substance to be encapsulated into at lease one (13) of material-feeding microchannels in a substrate in which these material-feeding microchannels (12, 13, 14) and a reaction microchannel (18) connected to these material-feeding microchannels are formed; feeding an envelop-forming fluid containing a material for forming envelopes into at least one of the other material-feeding microchannels (12, 14); and allowing the envelope-forming fluid and the fluid containing the encapsulated substance that converge in the reaction microchannel from each material-feeding microchannel to flow through the reaction microchannel while continuously maintaining the interface between the fluids formed at the confluence thereof.Type: ApplicationFiled: November 2, 2007Publication date: June 10, 2010Applicant: NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITYInventors: Yoshinobu Baba, Manabu Tokeshi, Noritada Kaji, Hideyoshi Harashima, Kentaro Kogure, Yasuo Shinohara, Hiroshi Kuramoto