Patents by Inventor Noritaka Iwai

Noritaka Iwai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibiotics targeting MreB
    Patent number: 7855228
    Abstract: The identification of MreB as essential for bacterial chromosome segregation provides a new target for antibiotic action. The MreB function is useful in the development of screening assays for new antibiotics, which may use, for example, genetic mutants in MreB, tests of MreB mediated chromosome segregation, and the like. In one embodiment of the invention, the antibiotic is an isothiourea compound, which may comprise a polyhalogenated benzyl group, e.g. at the 4 position, the 2,4 position, etc. A pharmaceutical composition comprising an MreB targeted antibiotic as an active agent is administered to a patient suffering from a microbial infection, particularly bacterial infections.
    Type: Grant
    Filed: February 8, 2006
    Date of Patent: December 21, 2010
    Assignees: The Board of Trustees of the Leland Stamford Junior University, Tokyo Institute of Technology
    Inventors: Zemer Gitai, Lucy Shapiro, Masaaki Wachi, Noritaka Iwai
  • Antibiotics targeting MreB
    Publication number: 20060241185
    Abstract: The identification of MreB as essential for bacterial chromosome segregation provides a new target for antibiotic action. The MreB function is useful in the development of screening assays for new antibiotics, which may use, for example, genetic mutants in MreB, tests of MreB mediated chromosome segregation, and the like. In one embodiment of the invention, the antibiotic is an isothiourea compound, which may comprise a polyhalogenated benzyl group, e.g. at the 4 position, the 2,4 position, etc. A pharmaceutical composition comprising an MreB targeted antibiotic as an active agent is administered to a patient suffering from a microbial infection, particularly bacterial infections.
    Type: Application
    Filed: February 8, 2006
    Publication date: October 26, 2006
    Inventors: Zemer Gitai, Lucy Shapiro, Masaaki Wachi, Noritaka Iwai