Patents by Inventor Noriyuki Hongo

Noriyuki Hongo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Reagent composition of glutamate dehydrogenase from pseudomonas
    Patent number: 5874078
    Abstract: A novel glutamate dehydrogenase derived from the genus Pseudomonas which is specific to L-glutamic acid, requires NAD.sup.+ and NADH as coenzymes, does not act on NADP.sup.+ and NADPH, is with an optimum pH 10.5-11.5 (oxidative deamination), a pH stability of 5-10 (at 25.degree. C.; 20 hours), an optimum temperature of about 60.degree. C. (oxidative deamination) and a molecular weight of about 280,000 (gel filtration) or about 41,000 (SDS-PAGE) and is not activated by ADP. A reagent composition for measuring an amount of ammonia characterized in containing a glutamate dehydrogenase which is not activated by ADP and is NADH-dependent, .alpha.-ketoglutaric acid or a salt thereof and NADH; and a reagent composition wherein urease or creatinine deiminase is further added to the above-mentioned reagent composition.
    Type: Grant
    Filed: January 4, 1996
    Date of Patent: February 23, 1999
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Noriyuki Hongo, Shizuo Hattori, Kazumi Yamamoto, Shinichi Teshima, Yoshihisa Kawamura
  • Glutamate dehydrogenase from Pseudomonas
    Patent number: 5773585
    Abstract: A novel glutamate dehydrogenase is derived from the genus Pseudomonas and is specific to L-glutamic acid, requires NAD.sup.+ and NADH as coenzymes, does not act on NADP.sup.+ and NADPH, has an optimum pH 10.5-11.5 (oxidative deamination), a pH stability of 5-10 (at 25.degree. C.; 20 hours), an optimum temperature of about 60.degree. C. (oxidative deamination) and a molecular weight of about 280,000 (gel filtration) or about 41,000 (SDS-PAGE) and is not activated by ADP.
    Type: Grant
    Filed: June 21, 1996
    Date of Patent: June 30, 1998
    Assignee: Toyo Boseki Kabushiki Kaisha
    Inventors: Noriyuki Hongo, Shizuo Hattori, Kazumi Yamamoto, Shinichi Teshima, Yoshihisa Kawamura