Abstract: It is possible to more appropriately perform fluorescence separation.

Abstract: It is possible to more appropriately perform fluorescence separation.

Abstract: The flow rate of light scattering fluid is measured more easily and at a higher speed. A flow rate measuring method according to the present disclosure includes: generating two or more speckle images by continually imaging light scattering fluid to be measured, while defining time shorter than spatial correlation disappearance time corresponding to time in which spatial correlation between speckle patterns generated by the light scattering fluid disappears as exposure time, at a time interval shorter than the spatial correlation disappearance time; and calculating direction and speed of flow of the light scattering fluid from time variation of the speckle patterns between the two or more speckle images, in which the speckle images are imaged by using an imaging device mounted with an area sensor and a pixel group of a part of the area sensor or by using an imaging device mounted with a line sensor.

Abstract: It is possible to more appropriately perform fluorescence separation.

Abstract: To provide an image analyzing technology capable of obtaining an image with less shading and with enough speckle contrast. An imaging apparatus includes: a light source that irradiates an imaging object with coherent light with a first irradiation condition and a second irradiation condition; a speckle imaging unit that captures a first speckle image obtained from scattered light of the imaging object irradiate at the first irradiation condition, and a second speckle image obtained from scattered light of the imaging object irradiate at the second irradiation condition; and an information processing unit that separates speckle images at boundaries of average luminance difference formed in the first speckle image and the second speckle image, connecting the separaged speckle images at the boundaries, and analyzes the combined speckle combined image.

Abstract: The flow rate of light scattering fluid is measured more easily and at a higher speed. A flow rate measuring method according to the present disclosure includes: generating two or more speckle images by continually imaging light scattering fluid to be measured, while defining time shorter than spatial correlation disappearance time corresponding to time in which spatial correlation between speckle patterns generated by the light scattering fluid disappears as exposure time, at a time interval shorter than the spatial correlation disappearance time; and calculating direction and speed of flow of the light scattering fluid from time variation of the speckle patterns between the two or more speckle images, in which the speckle images are imaged by using an imaging device mounted with an area sensor and a pixel group of a part of the area sensor or by using an imaging device mounted with a line sensor.

Abstract: Provided is a dental image acquisition apparatus that allows for acquisition of images in a plurality of imaging directions with a single captured image. The dental image acquisition apparatus includes an oral cavity insertion section and an image acquisition section. The oral cavity insertion section is inserted into an oral cavity. The image acquisition section has a light source. The oral cavity insertion section has an imaging unit that includes an imaging section and a light reflection section. The light reflection section is placed at a position opposed to the imaging section via an imaging target. Also, the dental image acquisition apparatus can further include an image processing section and an image display section. The image processing section calculates three-dimensional coordinates of the imaging target on the basis of the image acquired by the image acquisition section.

Abstract: To provide an image analyzing technology capable of obtaining an image with less shading and with enough speckle contrast. An imaging apparatus includes: a light source that irradiates an imaging object with coherent light with a first irradiation condition and a second irradiation condition; a speckle imaging unit that captures a first speckle image obtained from scattered light of the imaging object irradiate at the first irradiation condition, and a second speckle image obtained from scattered light of the imaging object irradiate at the second irradiation condition; and an information processing unit that separates speckle images at boundaries of average luminance difference formed in the first speckle image and the second speckle image, connecting the separaged speckle images at the boundaries, and analyzes the combined speckle combined image.

Abstract: Provided is an imaging technique capable of detecting a focus even in an imaging apparatus of a speckle image. The imaging apparatus includes a coherent light source that irradiates an imaging object with coherent light, an incoherent light source that irradiates the imaging object with incoherent light, a speckle imaging unit that captures a speckle image obtained from scattered light of the imaging object irradiated with the coherent light, a non-speckle imaging unit that captures a non-speckle image obtained from reflected light of the imaging object irradiated with the incoherent light, and a focus detection unit that detects a focus of the speckle imaging unit on the basis of a focal position of the non-speckle imaging unit.

Abstract: A fluid located at a certain depth in an imaging object can be imaged with high sensitivity and accuracy. As a result, an imaging technique by which information regarding the fluid can be accurately obtained is provided. An imaging apparatus includes: a light irradiation unit that irradiates a plurality of positions of an imaging object with coherent light as spots; a light detection unit that detects light, the light being emitted from the light irradiation unit and propagated in the imaging object; and an imaging unit that captures a speckle image obtained from scattered light of the imaging object, the scattered light being detected by the light detection unit.

Abstract: The imaging apparatus includes a coherent light source that irradiates an imaging object with coherent light, an incoherent light source that irradiates the imaging object with incoherent light, a speckle imaging unit that captures a speckle image obtained from scattered light of the imaging object irradiated with the coherent light, a non-speckle imaging unit that captures a non-speckle image obtained from reflected light of the imaging object irradiated with the incoherent light, and a focus detection unit that detects a focus of the speckle imaging unit on the basis of a focal position of the non-speckle imaging unit.

Abstract: The present technology provides a speckle imaging device including: an irradiation condition setting unit that sets an irradiation condition for coherent light with which an imaging object is irradiated; an imaging unit that captures scattered light obtained from the imaging object irradiated with the coherent light; an image generation unit that generates a speckle-enhanced image from a captured image captured by the imaging unit; and a leveling processing unit that generates a leveled speckle image from speckle-enhanced images corresponding to two or more different irradiation conditions.

Abstract: Provided is a highly accurate imaging technology that utilizes the speckle interference. The present technology provides a speckle imaging device including: an irradiation condition setting unit that sets an irradiation condition for coherent light with which an imaging object is irradiated; an imaging unit that captures scattered light obtained from the imaging object irradiated with the coherent light; an image generation unit that generates a speckle-enhanced image from a captured image captured by the imaging unit; and a leveling processing unit that generates a leveled speckle image from speckle-enhanced images corresponding to two or more different irradiation conditions.

Abstract: Provided is a highly accurate imaging technology that utilizes the speckle interference. The present technology provides a speckle imaging device including: an irradiation condition setting unit that sets an irradiation condition for coherent light with which an imaging object is irradiated; an imaging unit that captures scattered light obtained from the imaging object irradiated with the coherent light; an image generation unit that generates a speckle-enhanced image from a captured image captured by the imaging unit; and a leveling processing unit that generates a leveled speckle image from speckle-enhanced images corresponding to two or more different irradiation conditions.

Abstract: A nucleic acid amplifier for carrying out a nucleic acid amplification reaction is disclosed. The amplifier includes a plurality of wells configured to carry out the nucleic acid amplification reaction. The amplifier also include a heating unit provided for every well. The amplifier further includes a light source for irradiating excitation light of a specified wavelength to all of the wells. A fluorescence detection unit is provided for every well.

Abstract: According to an embodiment of the present disclosure, there is provided a biomolecule detection apparatus including a light emission unit, a measuring unit and an analysis unit. The light emission unit is configured to emit excitation light to living cells, the living cells having been in contact with an antitumor drug in advance. The measuring unit is configured to measure a Raman spectrum of the living cells. The analysis unit is configured to analyze whether or not the antitumor drug and a target biomolecule are bound with each other on the surface or inside of the living cells, based on the Raman spectrum.

Abstract: Provided is a microbead analysis method for a microbead. The microbead is formed in a columnar shape having a top surface and a bottom surface facing each other, as placed almost in parallel, and a side surface extending therefrom, and carries an identification pattern formed on at least one of the top surface and the bottom surface and a substance immobilized on a surface thereof having affinity to an analyte substance. The method includes detecting fluorescence emitted from the microbead surface due to interaction of the analyte substance with the substance having affinity to the analyte substance from a region including a region of the top surface and the bottom surface where there is no identification pattern formed and the side surface.

Abstract: The present disclosure relates to a method and apparatus for separating nucleic acids. A carrier may include a porous microbead having cation-exchangeable groups attached to the surface of the porous microbead. Capturing chains modified with positively charged functional groups and having a base sequence complementary to a target nucleic acid chain sequence are immobilized on to the surface of the porous microbead. In various embodiments, capturing chains are immobilized on to the surface of the porous microbead through an ion exchange bond or a covalent bond with the cation-exchangeable groups of the porous microbead. In some cases, the porous microbead has a number of through pores adapted to permit a solution to pass rapidly through the through pores and a number of diffusive pores adapted to permit a solute of the solution to diffuse into the diffusive pores.

Abstract: Provided is a microbead analysis method for a microbead. The microbead is formed in a columnar shape having a top surface and a bottom surface facing each other, as placed almost in parallel, and a side surface extending therefrom, and carries an identification pattern formed on at least one of the top surface and the bottom surface and a substance immobilized on a surface thereof having affinity to an analyte substance. The method includes detecting fluorescence emitted from the microbead surface due to interaction of the analyte substance with the substance having affinity to the analyte substance from a region including a region of the top surface and the bottom surface where there is no identification pattern formed and the side surface.

Abstract: Disclosed herein is a cell for testing microbeads, used for testing microbeads each formed in a cylindrical shape having an upper surface and a lower surface opposite to and substantially parallel to each other and a side surface continuous with the upper and lower surfaces, at least one of the upper surface and the lower surface being provided with an identification pattern, the cell including: a support substrate; and a cover disposed opposite to the support substrate, wherein a space between the support substrate and the cover forms a containing space in which to dispose the microbeads, and the distance between the support substrate and the cover is greater than the thickness of the microbeads and smaller than twice the thickness of the microbeads.