Patents by Inventor Noriyuki Satoh
Noriyuki Satoh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230060781Abstract: Provided is a method of assisting the detection of nonalcoholic steatohepatitis (NASH), which is far less invasive than liver biopsy and is based on simple operations that do not require skilled technical personnel. The present invention is a method of assisting the detection of NASH, which includes: a) measuring the amount of LDL-TG contained in a test blood sample isolated from a living body; b) measuring the amount of at least one component selected from the group consisting of LDL-C, LDL subfraction-C, IIDL-C, HDL subfraction-C, ApoB, ApoE, total cholesterol, ALT, and AST contained in the test blood sample; and c) determining the possibility of developing and/or having NASH by using the amount of LDL-TG in combination with the amount of the at least one component.Type: ApplicationFiled: February 4, 2021Publication date: March 2, 2023Applicants: Denka Company Limited, NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITYInventors: Noriyuki SATOH, Yasuki ITO, Toshihiro SAKURAI, Masahiro MIZUTA, Shu-Ping HUI, Kazuhiro NOUSO, Hiroyuki OKADA
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Publication number: 20220372546Abstract: A kit used for fractionation of small dense LDL cholesterol (sdLDL-C) in a sample, including: a first reagent composition having one or two or more activities selected from the group consisting of cholesterol esterase activity, cholesterol oxidase activity, and sphingomyelinase activity; and a second reagent composition for quantifying the sdLDL-C, in which in an absorption spectrum after storing the first reagent composition at 37° C. for 2 weeks, a ratio R1 represented by ABS400/ABS450 is 0.90 or more and 3.00 or less, and in an absorption spectrum after storing the second reagent composition at 37° C. for 2 weeks, a ratio R1 represented by ABS400/ABS450 is 0.90 or more and 8.00 or less.Type: ApplicationFiled: September 9, 2020Publication date: November 24, 2022Applicant: DENKA COMPANY LIMITEDInventors: Yasuki ITO, Noriyuki SATOH
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Publication number: 20220299535Abstract: This invention provides a method for quantifying cholesterol in small, dense LDL in two steps using an autoanalyzer without pretreatment of an analyte, wherein spontaneous color development of a reagent during storage is suppressed, a kit for quantification used in the method, and a method for preparing such kit.Type: ApplicationFiled: September 9, 2020Publication date: September 22, 2022Applicant: Denka Company LimitedInventors: Yasuki ITOH, Noriyuki SATOH
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Patent number: 11382952Abstract: A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.Type: GrantFiled: August 23, 2018Date of Patent: July 12, 2022Assignees: Sapporo Medical University, Sumitomo Pharma Co., Ltd.Inventors: Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Satoh, Kenjiro Kamiguchi, Rena Morita, Satoshi Nishizawa, Akari Takahashi
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Publication number: 20210011036Abstract: Provided are a method which enables more accurate quantification of lipoprotein cholesterol in a test sample, and a quantification reagent and a quantification kit used for this method. The present invention provides a quantification method for lipoprotein cholesterol in a test sample containing a lipoprotein optionally using a quantification reagent, the method including adding a phospholipid to the test sample or the quantification reagent. The present invention also provides a quantification reagent for cholesterol in a lipoprotein used in the method of the present invention, the quantification reagent containing a phospholipid. The present invention also provides a quantification kit for lipoprotein cholesterol used in the method of the present invention, the quantification kit containing a phospholipid.Type: ApplicationFiled: March 28, 2019Publication date: January 14, 2021Applicant: DENKA COMPANY LIMITEDInventors: Noriyuki SATOH, Makoto IKAIDA, Yuhko HIRAO
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Publication number: 20200318155Abstract: Disclosed are a method and reagent of quantifying cholesterol in triglyceride-rich lipoprotein (TRL-C) in a test sample in a more specific manner without requiring laborious operations. The method of quantifying cholesterol in triglyceride-rich lipoprotein (TRL-C) includes the steps of: (1) selectively eliminating cholesterol in lipoproteins other than triglyceride-rich lipoprotein (TRL) by allowing a cholesterol esterase having a molecular weight of more than 50 kDa and a surfactant(s) to act; and (2) quantifying the remaining TRL-C.Type: ApplicationFiled: May 23, 2017Publication date: October 8, 2020Applicant: DENKA SEIKEN CO., LTD.Inventors: Noriyuki SATOH, Makoto IKAIDA, Yuhko HIRAO, Yasuki ITOH
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Publication number: 20190054141Abstract: A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.Type: ApplicationFiled: August 23, 2018Publication date: February 21, 2019Applicants: Sapporo Medical University, Sumitomo Dainippon Pharma Co., Ltd.Inventors: Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Satoh, Kenjiro Kamiguchi, Rena Morita, Satoshi Nishizawa, Akari Takahashi
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Patent number: 10080776Abstract: A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.Type: GrantFiled: May 24, 2016Date of Patent: September 25, 2018Assignees: Sapporo Medical University, Sumitomo Dainippon Pharma Co., Ltd.Inventors: Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Satoh, Kenjiro Kamiguchi, Rena Morita, Satoshi Nishizawa, Akari Takahashi
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Publication number: 20180094287Abstract: A composition that efficiently produces cellulose includes cell extracts derived from a tunicate of ascidian class or yeast expressing tunicate cellulose synthase, at least one divalent cation of calcium ion and magnesium ion, cellobiose and UDP-glucose. The composition has a pH in the range of 6.6-7.2.Type: ApplicationFiled: April 20, 2016Publication date: April 5, 2018Inventors: Keisuke NAKASHIMA, Sakura KIKUCHI, Noriyuki SATOH
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Publication number: 20160367628Abstract: A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.Type: ApplicationFiled: May 24, 2016Publication date: December 22, 2016Applicants: Sapporo Medical University, Sumitomo Dainippon Pharma Co., Ltd.Inventors: Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Satoh, Kenjiro Kamiguchi, Rena Morita, Satoshi Nishizawa, Akari Takahashi
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Patent number: 9399760Abstract: A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.Type: GrantFiled: August 15, 2013Date of Patent: July 26, 2016Assignees: Sapporo Medical University, Sumitomo Dainippon Pharma Co., Ltd.Inventors: Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Satoh, Kenjiro Kamiguchi, Rena Morita, Satoshi Nishizawa, Akari Takahashi
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Patent number: 9204108Abstract: A vehicle periphery monitoring system is provided, in which by matching a behavior of a semitransparent tire image with an operation from a driver's viewpoint, a feeling of strangeness is reduced, an intuitive space perception is assisted and also a moving direction and a behavior of a vehicle can be easily perceived. In a side-view monitor system an image processing controller converts a real camera image including a blind spot into an image to be viewed from a driver's viewpoint to generate a blind spot image, and superimposes a semitransparent vehicle image which is obtained by making a vehicle viewed from the driver's viewpoint semitransparent and a semitransparent tire image which is obtained by making a tire semitransparent and displaying a behavior following a handle operation viewed from the driver's viewpoint on the blind spot image.Type: GrantFiled: December 7, 2009Date of Patent: December 1, 2015Assignee: Clarion Co., Ltd.Inventors: Noriyuki Satoh, Katsuichi Ishii
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Patent number: 9142129Abstract: A virtual-screen setup unit sets up a virtual screen in a seam of images captured by an image capturing unit, the virtual screen being orthogonal to a road surface and extending in a direction from a near side to a far side of the vehicle. A virtual-screen projection image generation unit performs conversion of the images captured by the image capturing unit for projection onto the virtual screen, and thereby generates a virtual-screen projection image. The virtual-screen projection image is displayed on the image display unit.Type: GrantFiled: March 8, 2011Date of Patent: September 22, 2015Assignee: Clarion Co., Ltd.Inventor: Noriyuki Satoh
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Patent number: 8886023Abstract: A see-through side view monitor system includes a camera, an external monitor, and an image processing controller having an image deformation unit configured to perform point-of-view conversion on a real camera image signal inputted from the camera into a blind-spot image that is viewed from the position of the driver's point of view. A vehicle cabin image formation unit is configured to form a vehicle cabin image that is viewed from the position of the driver's point of view. An image composition device is configured to generate a transparent display image showing a blind-spot image transmitted through a semi-see-through vehicle cabin image, and an image composition device is configured to generate an animation display image showing the blind-spot image to be shifted stepwise from the vehicle cabin image.Type: GrantFiled: July 2, 2010Date of Patent: November 11, 2014Assignee: Clarion Co., Ltd.Inventor: Noriyuki Satoh
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Publication number: 20140044686Abstract: A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.Type: ApplicationFiled: August 15, 2013Publication date: February 13, 2014Applicants: Dainippon Sumitomo Pharma Co., Ltd., Sapporo Medical UniversityInventors: Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Satoh, Kenjiro Kamiguchi, Rena Morita, Satoshi Nishizawa, Akari Takahashi
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Patent number: 8624977Abstract: A vehicle-peripheral image displaying system (a side view monitor system A1) comprises a side camera 1, a monitor 3 and an image processing controlling unit 2, wherein the image processing controlling unit 2 includes an image processor 43 configured to perform a viewpoint conversion of the actually shot camera image input from the side camera 1 into a virtual camera image which is to be converted as if it is viewed from the driver's eye position, an image memory 44 configured to store a vehicle interior image which is previously shot from the driver's eye position as a vehicle interior image, and a superimposing circuit 46 configured to make the vehicle interior image translucent to form a translucent vehicle interior image, to perform an image composition such that the translucent vehicle interior image is superimposed on the virtual camera image, and to produce a composite image which represents the virtual camera image transparently through the translucent vehicle interior image.Type: GrantFiled: February 19, 2009Date of Patent: January 7, 2014Assignee: Clarion Co., Ltd.Inventor: Noriyuki Satoh
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Patent number: 8541544Abstract: A molecular marker for detecting a cancer stem cell in a cell mass which is a subject of interest, wherein the molecular marker can be detected in a cancer stem cell contained in the subject of interest but cannot be detected in a normal cell and a cancer cell that is different from a cancer stem cell; a method for determining the presence or absence of a cancer stem cell in a subject of interest by using the molecular marker as an measure; a kit for determining the presence or absence of a cancer stem cell, which comprises at least a reagent for detecting the molecular marker; a polypeptide encoded by the molecular marker; an antibody capable of recognizing an epitope of an expression product of a gene derived from the molecular marker; a nucleic acid capable of inhibiting the expression of the molecular marker; and a nucleic acid vaccine comprising a gene derived from the molecular marker.Type: GrantFiled: October 27, 2009Date of Patent: September 24, 2013Assignees: Dainippon Sumitomo Pharma Co., Ltd., Sapporo Medical UniversityInventors: Toshihiko Torigoe, Yoshihiko Hirohashi, Noriyuki Satoh, Kenjiro Kamiguchi, Rena Morita, Satoshi Nishizawa, Akari Takahashi
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Publication number: 20120327238Abstract: A virtual-screen setup unit sets up a virtual screen in a seam of images captured by an image capturing unit, the virtual screen being orthogonal to a road surface and extending in a direction from a near side to a far side of the vehicle. A virtual-screen projection image generation unit performs conversion of the images captured by the image capturing unit for projection onto the virtual screen, and thereby generates a virtual-screen projection image. The virtual-screen projection image is displayed on the image display unit.Type: ApplicationFiled: March 8, 2011Publication date: December 27, 2012Applicant: CLARION CO., LTD.Inventor: Noriyuki Satoh
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Publication number: 20120249789Abstract: A vehicle peripheral image display system is provided, in which a semitransparent vehicle interior image is clearly distinguished from a virtual camera image regardless of a surrounding environment condition where a real camera image is obtained and a blind spot external situation can be clearly visually confirmed through according to a positional relationship with the vehicle. In a see-through side-view monitor system an image processing control unit includes an image processor performing a viewpoint conversion of an external image from a side camera into a virtual camera image viewed from a driver's viewpoint, a luminance-hue sensor judging luminance and hue of the external image, a luminance-hue conversion block automatically adjusting luminance and hue of a semitransparent vehicle interior image and a superimposing circuit superimposing the semitransparent vehicle interior image on the virtual camera image.Type: ApplicationFiled: December 7, 2009Publication date: October 4, 2012Applicant: CLARION CO., LTD.Inventor: Noriyuki Satoh
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Publication number: 20120242834Abstract: A vehicle periphery monitoring system is provided, in which by matching a behavior of a semitransparent tire image with an operation from a driver's viewpoint, a feeling of strangeness is reduced, an intuitive space perception is assisted and also a moving direction and a behavior of a vehicle can be easily perceived. In a side-view monitor system an image processing controller converts a real camera image including a blind spot into an image to be viewed from a driver's viewpoint to generate a blind spot image, and superimposes a semitransparent vehicle image which is obtained by making a vehicle viewed from the driver's viewpoint semitransparent and a semitransparent tire image which is obtained by making a tire semitransparent and displaying a behavior following a handle operation viewed from the driver's viewpoint on the blind spot image.Type: ApplicationFiled: December 7, 2009Publication date: September 27, 2012Applicant: CLARION CO., LTD.Inventors: Noriyuki Satoh, Katsuichi Ishii