Patents by Inventor Norma J. Tom

Norma J. Tom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline pyridazine compound
    Patent number: 8569488
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: October 29, 2013
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • CRYSTALLINE PYRIDAZINE COMPOUND
    Publication number: 20120108601
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Application
    Filed: December 23, 2011
    Publication date: May 3, 2012
    Applicants: Gilead Sciences, Inc., Gerhard Puerstinger, K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Crystalline pyridazine compound
    Patent number: 8106054
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: January 31, 2012
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Crystalline pyridazine compound
    Publication number: 20090036460
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Application
    Filed: July 3, 2008
    Publication date: February 5, 2009
    Applicants: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard Puerstinger
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Processes for the preparation of benzoimidazole derivatives
    Patent number: 7183414
    Abstract: The present invention relates to a process for preparing a compound of the formula I or a pharmaceutically acceptable salt, prodrug, hydrate or solvate thereof, wherein R1, R2, R3 and R4 are as defined herein. The compound of formula I is useful in the treatment of abnormal cell growth, such as cancer, in mammals.
    Type: Grant
    Filed: June 23, 2004
    Date of Patent: February 27, 2007
    Assignee: Pfizer Inc
    Inventors: Norma J. Tom, Michael J. Castaldi, David B. Ripin
  • Process and intermediates for pyridazinone antidiabetic agents
    Patent number: 6759534
    Abstract: The present invention relates to a process for preparing pyridazinone aldose reductase inhibitors which are useful in the prevention and/or treatment of diabetic complications such as diabetic neuropathy, diabetic retinopathy, diabetic nephropathy, diabetic cardiomyopathy, diabetic microangiopathy and diabetic macroangiopathy in mammals. The invention also relates to novel intermediates useful in preparing those aldose reductase inihibitors.
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: July 6, 2004
    Assignee: Pfizer Inc.
    Inventor: Norma J. Tom
  • Methods of making quinoline amides
    Patent number: 6657065
    Abstract: The present invention relates to methods of making quinoline amides of Formula I below, which are microsomal triglyceride transfer protein inhibitors and can be used as medicines. The present invention also relates to compounds that are used to make quinoline amides of Formula I and methods of making these compounds.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: December 2, 2003
    Assignee: Pfizer Inc
    Inventors: Norma J. Tom, David C. Whritenour
  • Process and intermediates for pyridazinone antidiabetic agents
    Publication number: 20030162969
    Abstract: The present invention relates to a process for preparing pyridazinone aldose reductase inhibitors which are useful in the prevention and/or treatment of diabetic complications such as diabetic neuropathy, diabetic retinopathy, diabetic nephropathy, diabetic cardiomyopathy, diabetic microangiopathy and diabetic macroangiopathy in mammals. The invention also relates to novel intermediates useful in preparing those aldose reductase inihibitors.
    Type: Application
    Filed: January 7, 2003
    Publication date: August 28, 2003
    Inventor: Norma J. Tom
  • Methods of making quinoline amides
    Publication number: 20020161233
    Abstract: The present invention relates to methods of making quinoline amides of Formula I below, which are microsomal triglyceride transfer protein inhibitors and can be used as medicines.
    Type: Application
    Filed: April 23, 2002
    Publication date: October 31, 2002
    Inventors: Norma J. Tom, David C. Whritenour
  • Method for preparing sodium-hydrogen exchanger type 1 inhibitor
    Patent number: 6441176
    Abstract: Methods of preparing NHE-1 disclosed. The NHE-1 inhibitors are useful for the reduction of tissue damage resulting from tissue ischemia.
    Type: Grant
    Filed: August 10, 2000
    Date of Patent: August 27, 2002
    Assignee: Pfizer Inc.
    Inventor: Norma J. Tom
  • Methods of making quinoline amides
    Patent number: 6417367
    Abstract: The present invention relates to methods of making quinoline amides of Formula I below, which are microsomal triglyceride transfer protein inhibitors and can be used as medicines. The present invention also relates to compounds that are used to make quinoline amides of Formula I and methods of making these compounds.
    Type: Grant
    Filed: August 8, 2001
    Date of Patent: July 9, 2002
    Assignee: Pfizer Inc.
    Inventors: Norma J. Tom, David C. Whritenour
  • Methods of making quinoline amides
    Publication number: 20020042516
    Abstract: The present invention relates to methods of making quinoline amides of Formula I below, which are microsomal triglyceride transfer protein inhibitors and can be used as medicines.
    Type: Application
    Filed: August 8, 2001
    Publication date: April 11, 2002
    Inventors: Norma J. Tom, David C. Whritenour