Patents by Inventor Norma Jacqueline Tom

Norma Jacqueline Tom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer
    Patent number: 6878848
    Abstract: A process for interconverting a mixture of cis-trans isomers of a compound of formula I into the substantially pure cis isomer. Cis isomers of formula I are useful intermediates in the synthesis of cis isomers of benzamide piperidine compounds which exhibit activity as NK-1 receptor antagonists.
    Type: Grant
    Filed: November 10, 2003
    Date of Patent: April 12, 2005
    Assignee: Pfizer Inc
    Inventors: John Michael Humphrey, Norma Jacqueline Tom
  • Heteroaromatic bicyclic derivatives useful as anticancer agents
    Patent number: 6867201
    Abstract: The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
    Type: Grant
    Filed: August 22, 2002
    Date of Patent: March 15, 2005
    Assignee: Pfizer Inc
    Inventors: John Charles Kath, Norma Jacqueline Tom, Eric David Cox, Samit Kumar Bhattacharya
  • Process for converting a cis-trans mixture of substituted benzylidene amines into the pure cis isomer
    Publication number: 20040254380
    Abstract: A process for interconverting a mixture of cis-trans isomers of a compound of formula I into the substantially pure cis isomer.
    Type: Application
    Filed: November 10, 2003
    Publication date: December 16, 2004
    Applicant: Pfizer Inc
    Inventors: John Michael Humphrey, Norma Jacqueline Tom
  • Substituted bicyclic derivatives useful as anticancer agents
    Patent number: 6541481
    Abstract: The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals with administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
    Type: Grant
    Filed: April 12, 2001
    Date of Patent: April 1, 2003
    Assignee: Pfizer Inc
    Inventors: John Charles Kath, Norma Jacqueline Tom, Zhengyu Liu, Eric David Cox, Joel Morris, Samit Kumar Bhattacharya
  • Heteroaromatic bicyclic derivatives useful as anticancer agents
    Publication number: 20030055049
    Abstract: The invention relates to compounds of the formula 1 1
    Type: Application
    Filed: August 22, 2002
    Publication date: March 20, 2003
    Applicant: Pfizer Inc.
    Inventors: John Charles Kath, Norma Jacqueline Tom, Eric David Cox, Samit Kumar Bhattacharya
  • Heteroaromatic bicyclic derivatives useful as anticancer agents
    Patent number: 6465449
    Abstract: The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals by administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
    Type: Grant
    Filed: January 20, 2000
    Date of Patent: October 15, 2002
    Assignee: Pfizer Inc.
    Inventors: John Charles Kath, Norma Jacqueline Tom, Eric David Cox, Samit Kumar Bhattacharya
  • Substituted bicyclic derivatives useful as anticancer agents
    Publication number: 20010034351
    Abstract: The invention relates to compounds of the formula 1 1
    Type: Application
    Filed: April 12, 2001
    Publication date: October 25, 2001
    Inventors: John Charles Kath, Norma Jacqueline Tom, Zhengyu Liu, Eric David Cox, Joel Morris, Samit Kumar Bhattacharya
  • Substituted bicyclic derivatives useful as anticancer agents
    Patent number: 6284764
    Abstract: The invention relates to compounds of the formula 1 and to pharmaceutically acceptable salts and solvates thereof, wherein A, X, R1, R3 and R4 are as defined herein. The invention also relates to methods of treating abnormal cell growth in mammals with administering the compounds of formula 1 and to pharmaceutical compositions for treating such disorders which contain the compounds of formula 1. The invention also relates to methods of preparing the compounds of formula 1.
    Type: Grant
    Filed: January 20, 2000
    Date of Patent: September 4, 2001
    Assignee: Pfizer Inc.
    Inventors: John Charles Kath, Norma Jacqueline Tom, Zhengyu Liu, Eric David Cox, Joel Morris, Samit Kumar Bhattacharya