Patents by Inventor Norma Tom

Norma Tom has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing aficamten
    Patent number: 11932631
    Abstract: Provided herein is a process for the preparation of (R)—N-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide, intermediates thereof, and salts of the foregoing.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: March 19, 2024
    Assignee: CYTOKINETICS, INC.
    Inventors: Denise Andersen, Matthew Pfeiffer, Norma Tom, Bradley P. Morgan
  • PROCESS FOR PREPARING AFICAMTEN
    Publication number: 20230045450
    Abstract: Provided herein is a process for the preparation of (R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide, intermediates thereof, and salts of the foregoing.
    Type: Application
    Filed: August 2, 2022
    Publication date: February 9, 2023
    Inventors: Denise ANDERSEN, Matthew PFEIFFER, Norma TOM, Bradley P. MORGAN
  • POLYMORPHS OF (R)-N-(5-(5-ETHYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE
    Publication number: 20220315571
    Abstract: Provided herein are polymorphs of (R)-N-(5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-1-methyl-1H-pyrazole-4-carboxamide, compositions thereof, methods of preparation thereof, and methods of their uses.
    Type: Application
    Filed: July 16, 2020
    Publication date: October 6, 2022
    Inventors: Norma TOM, Matthew PFEIFFER, Denise ANDERSEN, Qi GAO
  • POLYMORPHS OF (R)-N-(5-(5-ISOPROPYL-1,2,4-OXADIAZOL-3-YL)-2,3-DIHYDRO-1H-INDEN-1-YL)-2-METHYL-2H-TETRAZOLE-5-CARBOXAMIDE
    Publication number: 20220274969
    Abstract: Provided herein are polymorphs of (R)—N-(5-(5-isopropyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl)-2-methyl-2H-tetrazole-5-carboxamide, compositions thereof, methods of preparation thereof, and methods of their uses.
    Type: Application
    Filed: July 16, 2020
    Publication date: September 1, 2022
    Inventors: Norma TOM, Denise ANDERSEN
  • Processes for the Preparation of Benzoimidazole Derivatives
    Publication number: 20070088032
    Abstract: The present invention relates to a process for preparing a compound of the formula I or a pharmaceutically acceptable salt, prodrug, hydrate or solvate thereof. wherein R1, R2, R3 and R4 are as defined herein. The compound of formula I is useful in the treatment of abnormal cell growth, such as cancer in mammals.
    Type: Application
    Filed: December 5, 2006
    Publication date: April 19, 2007
    Inventors: Norma Tom, David Ripin, Michael Castaldi
  • Processes for the preparation of benzoimidazole derivatives
    Publication number: 20050020625
    Abstract: The present invention relates to a process for preparing a compound of the formula I or a pharmaceutically acceptable salt, prodrug, hydrate or solvate thereof, wherein R1, R2, R3 and R4 are as defined herein. The compound of formula I is useful in the treatment of abnormal cell growth, such as cancer, in mammals.
    Type: Application
    Filed: June 23, 2004
    Publication date: January 27, 2005
    Inventors: Norma Tom, David Ripin, Michael Castaldi