Patents by Inventor Norman A. Paradis

Norman A. Paradis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10555870
    Abstract: A system for improving cardiac output of a patient suffering from pulseless electrical activity or shock and yet displays myocardial wall motion including: a sensor to detect myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase, a device to prompt the application of or apply a compressive force repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion.
    Type: Grant
    Filed: October 24, 2017
    Date of Patent: February 11, 2020
    Assignee: ZOLL Medical Corporation
    Inventors: Norman Paradis, David Barash, Henry R. Halperin, Gary A. Freeman
  • Patent number: 10548763
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Grant
    Filed: March 28, 2017
    Date of Patent: February 4, 2020
    Assignee: Zoll Circulation, Inc.
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Publication number: 20190374247
    Abstract: Devices for improving vascular cannulation by increasing the probability of, and decreasing the time until, successful puncture of vascular and other structures. In its simplest form, a device composed of multiple connected needles in a linear or curvilinear array that is inserted perpendicular to the vessel such that one or more needles are likely to puncture the vessel. Alternatively, a gantry system incorporating a linear or curvilinear array of needle guides that allows sequential insertion of one or more needles in a linear pattern. The devices herein described may be used to successfully puncture any anatomic structure of interest.
    Type: Application
    Filed: June 9, 2019
    Publication date: December 12, 2019
    Inventor: Norman A. Paradis
  • Publication number: 20180133105
    Abstract: A system for improving cardiac output of a patient suffering from pulseless electrical activity or shock and yet displays myocardial wall motion including: a sensor to detect myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase, a device to prompt the application of or apply a compressive force repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion.
    Type: Application
    Filed: October 24, 2017
    Publication date: May 17, 2018
    Inventors: Norman Paradis, David Barash, Henry R. Halperin, Gary A. Freeman
  • Publication number: 20180021216
    Abstract: A method to increase the overall hemodynamic efficacy of cardiopulmonary resuscitation (CPR) by alternating between chest compression-decompression cycles optimized to either cardiac output or venous return. The phases of cardiac output and venous return enhancement may themselves by adjusted in their duration and character. The method may enhance mechanical and manual techniques delivered to the anterior or circumferential chest, and be synchronized to adjunctive techniques such as airway, ventilatory or abdominal therapies.
    Type: Application
    Filed: July 21, 2017
    Publication date: January 25, 2018
    Inventor: Norman A. Paradis
  • Publication number: 20170354534
    Abstract: Systems, methods and devices for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Application
    Filed: March 28, 2017
    Publication date: December 14, 2017
    Inventors: Norman A. Paradis, B. Stuart Trembly
  • Patent number: 9833378
    Abstract: A system for improving cardiac output of a patient suffering from pulseless electrical activity or shock and yet displays myocardial wall motion including: a sensor to detect myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase, a device to prompt the application of or apply a compressive force repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion.
    Type: Grant
    Filed: February 10, 2016
    Date of Patent: December 5, 2017
    Assignee: ZOLL Medical Corporation
    Inventors: Norman Paradis, David Barash, Henry R. Halperin, Gary A. Freeman
  • Publication number: 20170336247
    Abstract: A method for diagnosing or predicting the risk of shock, the method incorporating an algorithmic combination of optical, electromagnetic, and other sensors, along with their anatomic and temporal patterns. A method for developing the algorithms through iterative optimization using machine learning.
    Type: Application
    Filed: July 29, 2017
    Publication date: November 23, 2017
    Inventor: Norman A. Paradis
  • Patent number: 9719842
    Abstract: A method for diagnosing or predicting the risk of shock, the method incorporating an algorithmic combination of optical, electromagnetic, and other sensors, along with their anatomic and temporal patterns. A method for developing the algorithms through iterative optimization using machine learning.
    Type: Grant
    Filed: August 29, 2014
    Date of Patent: August 1, 2017
    Inventor: Norman A. Paradis
  • Publication number: 20170052936
    Abstract: A computer software program that enhances the readability of electronic documents containing abbreviation or acronym. The program automatically identifies abbreviations and acronyms based on their first definitional use. It then identifies each subsequent use of the abbreviation or acronym and substitutes the appropriate full word or phrase for the abbreviation or acronym. Optionally or alternatively, the program may also identify abbreviations or acronyms that are in general use but have not been specifically defined within the document and offers substitution of the appropriate full word or phrase.
    Type: Application
    Filed: August 21, 2015
    Publication date: February 23, 2017
    Inventors: Norman A. Paradis, Aidan B. Paradis
  • Publication number: 20160361228
    Abstract: The present invention is a method for improving hemodynamics and clinical outcome of patients suffering cardiac arrest and other low-flow states by combination of circumferential constriction and anteroposterior compression decompression of the chest cardiopulmonary resuscitation. Anteroposterior compression decompression may be provided by a piston mechanism attached to a gantry above the patient. Circumferential constriction may be achieved by inflation of pneumatic bladders or shortening of a band. The on-off sequence and relative force of circumferential constriction and anteroposterior compression decompression may be adjusted so as to improve efficacy.
    Type: Application
    Filed: June 13, 2016
    Publication date: December 15, 2016
    Inventor: Norman A. Paradis
  • Publication number: 20160242992
    Abstract: A method for treating chest wall injuries, including rib fractures, flail chest injuries or surgical incisions. The method comprising creating a localized airtight compartment external to the chest wall and fully covering the area of injury, varying the pressure within the compartment, and providing dynamic real-time counter forces that act reciprocal to the intrathoracic pressure changes that occur during ventilation. In a preferred embodiment, the apparatus has the capability of sensing the patient's chest wall motion created by ventilation, a pressure control component capable of varying the pressure within the airtight compartment such that it opposes pressure changes within the chest. Said apparatus would be particularly useful in preventing the paradoxical movement of flail chest injuries. The method would also lessen pain experienced by patients with thoracic injuries such as rib fractures and post operative suffering.
    Type: Application
    Filed: February 23, 2016
    Publication date: August 25, 2016
    Inventor: Norman A. Paradis
  • Publication number: 20160158098
    Abstract: A system for improving cardiac output of a patient suffering from pulseless electrical activity or shock and yet displays myocardial wall motion including: a sensor to detect myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase, a device to prompt the application of or apply a compressive force repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion.
    Type: Application
    Filed: February 10, 2016
    Publication date: June 9, 2016
    Inventors: Norman PARADIS, David Barash, Henry R. Halperin, Gary Freeman
  • Patent number: 9259543
    Abstract: A method for improving the cardiac output of a patient who is suffering from pulseless electrical activity or shock and yet still displays some myocardial wall motion including sensing myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase. In such cases, a compressive force is repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion. Also incorporated may be a logic circuit capable of utilizing multiple sensing modalities and optimizing the synchronization pattern between multiple phasic therapeutic modalities and myocardial residual mechanical function.
    Type: Grant
    Filed: July 14, 2011
    Date of Patent: February 16, 2016
    Assignee: Zoll Medical Corporation
    Inventors: Norman Paradis, David Barash, Henry R. Halperin, Gary Freeman
  • Publication number: 20150250643
    Abstract: A method for utilizing heat transfer parameters or energy expenditure of devices providing controlled hypothermia, normothermia or hyperthermia to detect changes, or the absence of changes, a patient's endogenous set-point temperature; which is not available during exogenously induced targeted temperature management. A particular embodiment would allow detection of fever in patients undergoing targeted temperature managed.
    Type: Application
    Filed: March 9, 2015
    Publication date: September 10, 2015
    Inventor: Norman A. Paradis
  • Publication number: 20150025812
    Abstract: A method for the discovery, development and clinical application of multidimensional multiplex synthetic biomarker assays based on patterns of cellular response. After stimulation or inhibition, a selected multiplicity of cell types are assayed for a multiplicity of cellular or molecular responses, and known machine learning techniques are used to synthesize the cellular responses into an optimized clinical biomarker. The computationally derived algorithm includes the relationships within and between the component steps so as to produce an optimized synthetic clinical biomarker. During discover of the assay one or more of the component steps are repeated iteratively until a final clinically optimized algorithm is produced. Such a multidimensional multiplex cell response assay may provide improved diagnostic performance with respect to entities such as immune status, infection, and antibiotic and vaccine efficacy, among others.
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Inventor: Norman A. Paradis
  • Publication number: 20150011844
    Abstract: A method for diagnosing or predicting the risk of shock, the method incorporating an algorithmic combination of optical, electromagnetic, and other sensors, along with their anatomic and temporal patterns. A method for developing the algorithms through iterative optimization using machine learning.
    Type: Application
    Filed: August 29, 2014
    Publication date: January 8, 2015
    Inventor: Norman A. Paradis
  • Patent number: 8870797
    Abstract: A method for improving the cardiac output of a patient who is suffering from pulseless electrical activity or shock and yet still displays some myocardial wall motion including sensing myocardial activity to determine the presence of residual left ventricular pump function having a contraction or ejection phase and a filling or relaxation phase. In such cases, a compressive force is repeatedly applied to the chest based on the sensed myocardial activity such that the compressive force is applied during at least some of the ejection phases and is ceased during at least some of the relaxation phases to permit residual cardiac filling, thereby enhancing cardiac output and organ perfusion. Also incorporated may be a logic circuit capable of utilizing multiple sensing modalities and optimizing the synchronization pattern between multiple phasic therapeutic modalities and myocardial residual mechanical function.
    Type: Grant
    Filed: January 11, 2010
    Date of Patent: October 28, 2014
    Inventor: Norman A. Paradis
  • Publication number: 20130337445
    Abstract: A method and apparatus for the discovery, development and clinical application of multiplex synthetic assays based on patterns of free radicals, indicators of oxidative or nitrosative stress, or indicators of the redox state of biologic fluids and tissue specimens. These individual measurements are combined into an optimized clinical biomarker using known well-known mathematical, machine learning techniques.
    Type: Application
    Filed: June 19, 2013
    Publication date: December 19, 2013
    Inventor: Norman A. Paradis
  • Publication number: 20120196762
    Abstract: A method for deriving a multiplex cell response assay (MCRA), the method comprising: obtaining at least one specimen that has been phenotyped and classified with respect to the disease of interest using existing diagnostic techniques; adding of at least one stimulatory or inhibitory agent; isolating or separating at least one cell type; performing a multiplex measurement of cellular responses in each of the at least one cell type; and computationally deriving a clinically useful biomarker algorithm.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 2, 2012
    Inventor: Norman A. Paradis