Abstract: An improved hypodermic syringe (5) with safety shield, and method of using same, is disclosed. The hypodermic syringe has an elongate hollow cylindrical barrel (7) with a grip flange (11) formed at a first end (8) thereof, and a hypodermic needle (12) attached to a second end (9) thereof, and in fluid communication with the hollow interior of the barrel. The syringe is provided with a reciprocable plunger assembly (15). An elongate hollow cylindrical safety shield (20) is positioned coaxially about the barrel in a retracted position so that the needle projects axially out of the safety shield for use. The safety shield is constructed and arranged for movement on the barrel from the retracted position into an extended position in which the needle is housed within the safety shield. The safety shield has an integral end shield (36) which can be moved into a closed position transverse to the length of the safety shield for fully enclosing the needle within the safety shield.