Abstract: Master valve and cable hanger system for deploying and making electrical connection to an electric submersible pump. A landing for the cable hanger (50) is in the through bore below the valve closure element. The landing has a seal area and a bore transverse to the through bore penetrating into the seal area for allowing electric connection to the pump. The cable hanger has a seal section having longitudinally spaced apart seals engageable with an interior of the seal area, electrical contacts disposed between the seals, and a lockdown profile. Flow ports are arranged to bypass seal area and seal section. A blanking plug (58) is disposed in the transverse bore to seal the seal area prior to insertion of the cable hanger.

Abstract: Disclosed herein is a device capable of high efficiency DNA electrotransfer into cells via a single capacitive discharge. The principle of this system relates to the storage of a quantum of charge on a capacitor which is then discharged through an electrode array configured to produce an electric field having electric field potential gradients focused through a region by the array configuration and of sufficient in strength for efficient electrotransfer of DNA into cells. This DNA, or related ribonucleic acid molecules or indeed other charged molecules, upon entering the cells, can affect changes in biological function.

Abstract: Embodiments of the present invention provide an electroporation system comprising an electroporation probe having at least two contiguous electrodes configured to be inserted into biological tissue for electroporation treatment, and a pulse generator electrically connected to the probe and configured to drive the electroporation probe using a sequence of one or more electric pulses to cause current transmission through the probe and induce a non-uniform electric field in the biological tissue proximate the probe electrodes. Treatment tissue can be targeted by controlling the probe configuration, carrier solution characteristics and parameters of the electroporation pulse sequence to achieve predictable electroporation outcomes. This electroporation control method can also reduce potentially toxic effects of electroporation treatment.

Abstract: Embodiments of the present invention provide an electroporation system comprising an electroporation probe having at least two contiguous electrodes configured to be inserted into biological tissue for electroporation treatment, and a pulse generator electrically connected to the probe and configured to drive the electroporation probe using a sequence of one or more electric pulses to cause current transmission through the probe and induce a non-uniform electric field in the biological tissue proximate the probe electrodes. Treatment tissue can be targeted by controlling the probe configuration, carrier solution characteristics and parameters of the electroporation pulse sequence to achieve predictable electroporation outcomes. This electroporation control method can also reduce potentially toxic effects of electroporation treatment.

Abstract: An implantable band for placement around an anatomical passageway, such as the stomach or other lumen, has the inner surfaces at each end attached to each other in the operative position. One end may include a passageway through which the other end extends. A lateral member may extend from the surface at one end and engage the other end.

Abstract: A gastric band has a balloon shaped and dimensioned to circumscribe the stomach at a predetermined location and a belt extending about the balloon. Further, a linking layer is positioned between the balloon and the belt, wherein the linking layer is harder than either the balloon or the belt. Additionally, the belt includes a first latching member at a first end of the gastric band and second latching member at a second end of the gastric band, the first latching member and the second latching member being shaped and dimensioned for selective engagement to secure the gastric band about a stomach of a patient, wherein the first latching member and second latching member are composed of different materials.

Abstract: A gastric band includes a band body having a first end and a second end. The band body includes a latching mechanism. The latching mechanism is composed of a shell member at the first end of the band body and a collar member at the second end of the band body, the shell member and collar member being shaped and dimensioned for selective locking and unlocking in a manner creating a loop of the gastric band for positioning about a stomach wall.

Abstract: An implantable band for placement around an anatomical passageway, such as the stomach or other lumen, has the inner surfaces at each end attached to each other in the operative position. One end may include a passageway through which the other end extends. A lateral member may extend from the surface at one end and engage the other end.

Abstract: An implantable band for placement around an anatomical passageway, such as the stomach or other lumen, includes a transverse attachment mechanism, such as a dovetail connection or a lateral member disposed in a spiral path.