Patents by Inventor Norman Eugene Ohler

Norman Eugene Ohler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic side chain containing, n-substituted metalloprotease inhibitors
    Patent number: 6949545
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the compounds have a structure according to the following Formula (I): where R1, R2, R3, n, A, E, X, G, G?, M and Z have the meanings described in the specification and the claims, as well as optical isomers, diastereomers and enantiomers of Formula I, and pharmaceutically-acceptable salts, biohydrolyzable amides, esters, and imides thereof. Also described are pharmaceutical compositions comprising these compounds, and methods of treating metalloprotease-related maladies using the compounds or the pharmaceutical compositions.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: September 27, 2005
    Assignee: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steven Karl Laughlin, Michael George Natchus, Biswanath De, Paul Mitchell Hershberger
  • Beta disubstituted metalloprotease inhibitors
    Publication number: 20040142975
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes.
    Type: Application
    Filed: December 23, 2003
    Publication date: July 22, 2004
    Applicant: The Procter &Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Kelly Michelle Solinsky, Neil Gregory Almstead, Biswanath De, Michael George Natchus
  • Heterocyclic side chain containing, n-substituted metalloprotease inhibitors
    Publication number: 20040127498
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes.
    Type: Application
    Filed: January 16, 2004
    Publication date: July 1, 2004
    Applicant: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steyen Karl Laughlin, Michael George Natchus, Biswanath De, Paul Mitchell Hershberger
  • Beta disubstituted metalloprotease inhibitors
    Patent number: 6696456
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the compounds have a structure according to the following Formula (I): where R1, R2, R3, R4, R5, R6, G and Z have the meanings described in the specification. This invention also includes optical isomers, diastereomers and enantiomers of Formula I, and pharmaceutically-acceptable salts, biohydrolyzable amides, esters, and imides thereof. Also described are pharmaceutical compositions comprising these compounds, and methods of treating metalloprotease-related maladies using the compounds or the pharmaceutical compositions.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: February 24, 2004
    Assignee: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Kelly Michelle Solinsky, Neil Gregory Almstead, Biswanath De, Michael George Natchus
  • Heterocyclic side chain containing metalloprotease inhibitors
    Publication number: 20030171400
    Abstract: The compounds have a structure according to the following Formula (I): 1
    Type: Application
    Filed: September 18, 2002
    Publication date: September 11, 2003
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steven Karl Laughlin, Michael George Natchus, Biswanath De
  • Heterocyclic side chain containing, n-substituted metalloprotease inhibitors
    Publication number: 20030139414
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes.
    Type: Application
    Filed: September 13, 2002
    Publication date: July 24, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steven Karl Laughlin, Michael George Natchus, Biswanath De, Paul Mitchell Hershberger