Patents by Inventor Norman H. Rogers

Norman H. Rogers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial compounds
    Patent number: 4267316
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: June 14, 1979
    Date of Patent: May 12, 1981
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Esters of monic and isomonic acids
    Patent number: 4256879
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: June 11, 1979
    Date of Patent: March 17, 1981
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Antibacterial compounds
    Patent number: 4256762
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: May 21, 1979
    Date of Patent: March 17, 1981
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Antibacterial compounds, processes for their preparation and compositions containing them
    Patent number: 4248887
    Abstract: This invention relates to antibacterial compounds and in particular to a class of esters which have antibacterial activity against certain Gram-positive and Gram-negative organisms, and also possess anti-mycoplasmal activity. The compounds are therefore of value in the treatment of human and veterinary infections.
    Type: Grant
    Filed: March 19, 1979
    Date of Patent: February 3, 1981
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Antibacterial compounds
    Patent number: 4237161
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: August 7, 1978
    Date of Patent: December 2, 1980
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Antibacterial compounds
    Patent number: 4235784
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: January 27, 1978
    Date of Patent: November 25, 1980
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Antibacterial compounds
    Patent number: 4226880
    Abstract: A compound of formula (II), named pseudomonic acid C or a salt or ester thereof: ##STR1## has antibacterial and anti-mycoplasma activity, and can be produced either by fermentation of Pseudomonas fluorescens, or by de-oxygenation of pseudomonic acid A, the compound having an epoxide in place of the double bond. The compounds are therefore useful in the treatment of human and veterinary bacterial and mycoplasma-induced infections.
    Type: Grant
    Filed: May 24, 1979
    Date of Patent: October 7, 1980
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Isolation of organic acids
    Patent number: 4222942
    Abstract: A process for the purification of pseudomonic acid, particularly suitable for isolating the compound when prepared by bacterial culture, comprises making a solution in an organic solvent of the acidic components of the crude preparation substantially free of the neutral components. The polarity of the organic solvent is adjusted so that the pseudomonic acid crystallizes. This may be achieved either by adding a non-polar diluent such as n-heptane to the solution for example in methyl iso-butyl ketone; or by employing a di-C.sub.1-6 alkyl ether in which the acidic components dissolve and then crystallize out.
    Type: Grant
    Filed: September 29, 1978
    Date of Patent: September 16, 1980
    Assignee: Beecham Group Limited
    Inventors: Peter J. O'Hanlon, Maurice C. Woodford, Norman H. Rogers
  • Antibacterial compounds
    Patent number: 4217447
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: June 14, 1979
    Date of Patent: August 12, 1980
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Antibacterial compounds
    Patent number: 4217448
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: August 12, 1980
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Antibacterial compounds
    Patent number: 4216223
    Abstract: A thiol acid and esters thereof of formula (II): ##STR1## wherein R is hydrogen, a salt forming ion or a pharmaceutically acceptable ester-forming radical, have antibacterial and antimycoplasmal activity and are therefore useful in the treatment of human and veterinary bacterial and mycoplasmal infections.
    Type: Grant
    Filed: November 22, 1978
    Date of Patent: August 5, 1980
    Assignee: Beecham Group Limited
    Inventors: John P. Clayton, Norman H. Rogers, Steven Coulton
  • Antibacterial compounds
    Patent number: 4205002
    Abstract: A compound of formula (II), named pseudomonic acid C or a salt or ester thereof: ##STR1## has antibacterial and anti-mycoplasma activity, and can be produced either by fermentation of Pseudomonas fluorescens, or by de-oxygenation of pseudomonic acid A, the compound having a epoxide in place of the double bond. The compounds are therefore useful in the treatment of human and veterinary bacterial and mycoplasma-induced infections.
    Type: Grant
    Filed: October 27, 1978
    Date of Patent: May 27, 1980
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Peter J. O'Hanlon
  • Antibacterially active amides
    Patent number: 4200635
    Abstract: Carboxylic acid amides of formula (II): ##STR1## where R.sup.1 and R.sup.2 represent a variety of hydrocarbon or heterocyclic groups, possess antibacterial activity and antimycoplasmal activity and are therefore of value in the treatment of human and veterinary bacterial and mycoplasmal infections.
    Type: Grant
    Filed: November 3, 1978
    Date of Patent: April 29, 1980
    Assignee: Beecham Group Limited
    Inventor: Norman H. Rogers
  • 3-Carbamoyl substituted-7-ureido substituted cephalosporins
    Patent number: 4198503
    Abstract: A class of 3-carbamoyloxymethyl-7-.alpha.-acylureido cephalosporins have a broad spectrum of antibacterial activity.
    Type: Grant
    Filed: August 2, 1978
    Date of Patent: April 15, 1980
    Assignee: Beecham Group Limited
    Inventors: Norman H. Rogers, Robert Stevenson
  • Antibacterial compounds
    Patent number: 4166863
    Abstract: Esters of an acid of formula: ##STR1## which is termed "monic acid" have activity against Gram-positive and Gram-negative organisms.
    Type: Grant
    Filed: January 30, 1978
    Date of Patent: September 4, 1979
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Ketones
    Patent number: 4152337
    Abstract: A novel acid of formula: ##STR1## which is termed "monic acid" and is prepared from pseudomonic acid, is a useful intermediate for the preparation of esters thereof.
    Type: Grant
    Filed: January 30, 1978
    Date of Patent: May 1, 1979
    Assignee: Beecham Group Limited
    Inventors: Kong Luk, John P. Clayton, Norman H. Rogers
  • Pseudomonic acid amide antibacterial compounds
    Patent number: 4139629
    Abstract: Antibacterial compounds, preparation thereof, human and veterinary compositions containing the same and method of administration of the compositions without producing penicillinase and being amides of pseudomonic acid. The pseudomonic acid amides are effective against Gram-positive and Gram-negative organisms and possess good antimycoplasmal activity.
    Type: Grant
    Filed: February 14, 1977
    Date of Patent: February 13, 1979
    Assignee: Beecham Group Limited
    Inventor: Norman H. Rogers