Patents by Inventor Norman Radin

Norman Radin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amino ceramide-like compounds and therapeutic methods of use
    Publication number: 20050239862
    Abstract: Novel amino ceramide-like compounds (1) are provided which inhibit glucosyl ceramide (GlcCer) formation by inhibiting the enzyme GlcCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer synthase inhibition activity and are therefore highly useful in therapeutic methods for treating various conditions and diseases associated with altered glycosphingolipid levels.
    Type: Application
    Filed: March 10, 2005
    Publication date: October 27, 2005
    Applicant: The Regents of the University of Michigan
    Inventors: James Shayman, Norman Radin
  • Amino ceramide-like compounds and therapeutic methods of use
    Publication number: 20050049235
    Abstract: The present invention provides amino ceramide-like compounds which inhibit glucosyl ceramide (GlyCer) formation by inhibiting the enzyme GlyCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer synthase inhibition activity and are therefore useful in therapeutic methods for treating various conditions and diseases associated with altered glycosphingolipid levels.
    Type: Application
    Filed: May 5, 2004
    Publication date: March 3, 2005
    Applicant: The Regents of the University of Michigan
    Inventors: James Shayman, Norman Radin