Abstract: The present invention relates to compounds of formula (I) wherein G1 to G8 are as defined herein. The compounds are PK inhibitors and as such represent a new approach to treating pathogenic infections, including multidrug resistant pathogens. Disclosed herein are the compounds of formula (I), pharmaceutical compositions comprising the compounds of formula (I) and their use in the treatment of antimicrobial infection.

Abstract: A system for efficiently displaying medical data to a user. For one or more of the image series, the system displays a thumbnail image representing the image series in a secondary segment of a display. In response to a selection of one of the displayed thumbnail images the system displays in the secondary segment a positioning grid with multiple sections, each section representing a section of a separate primary segment of the display that does not overlap the secondary segment. In response to a selection of one of the sections in the positioning grid the system updates the display to cause an image in the image series corresponding to the selected thumbnail image to be displayed in the section of the primary segment of the display represented by the selected section of the positioning grid.

Abstract: A system for efficiently displaying medical data to a user. For one or more of the image series, the system displays a thumbnail image representing the image series in a secondary segment of a display. In response to a selection of one of the displayed thumbnail images the system displays in the secondary segment a positioning grid with multiple sections, each section representing a section of a separate primary segment of the display that does not overlap the secondary segment. In response to a selection of one of the sections in the positioning grid the system updates the display to cause an image in the image series corresponding to the selected thumbnail image to be displayed in the section of the primary segment of the display represented by the selected section of the positioning grid.

Abstract: A method, system and user interface for synthetic image generation for magnetic resonance (MR) imaging is described. A plurality of MR imaging data sets is received, each data set being acquired at a different value for a MR acquisition parameter. A response value for a particular property of tissues is determined, based on a calculated fit of each pixel to a property response model. A synthetic image is generated for a selected value of the MR acquisition parameter, based on the determined response value. An option is provided to dynamically change the selected value of the MR acquisition parameter and the synthetic image is re-generated for the changed value. An option may be provided to dynamically change the value. Another option may be provided to calculate a reliability measure for the synthetic image.

Abstract: A method, system and user interface for synthetic image generation for magnetic resonance (MR) imaging is described. A plurality of MR imaging data sets is received, each data set being acquired at a different value for a MR acquisition parameter. A response value for a particular property of tissues is determined, based on a calculated fit of each pixel to a property response model. A synthetic image is generated for a selected value of the MR acquisition parameter, based on the determined response value. An option is provided to dynamically change the selected value of the MR acquisition parameter and the synthetic image is re-generated for the changed value. An option may be provided to dynamically change the value. Another option may be provided to calculate a reliability measure for the synthetic image.

Abstract: There is disclosed herein an anti-loading tray assembly, for mounting upon the lower frame of conventional nestable shopping carts, at a position below the basket so as to prevent pilferage by loading of articles onto the cart below the basket. The tray includes a plurality of interconnecting elongated struts, cross members of a size, shape and arrangement to define a forwardly-and-downwardly sloping, plane-like area with lateral wings which prevent loading of articles upon either the tray or lower frame of the cart. Simplified means of connection of the tray to existing structure of the cart's frame provides that the anti-loading tray may be an economical add-on feature. The arrangement provides a simple inexpensive tray which is easily manufactured and may be readily installed both at the factory and on existing carts in the field.