Patents by Inventor Normand Hébert

Normand Hébert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 6-acetylmorphine analogs, and methods for their synthesis and use
    Patent number: 11628216
    Abstract: The present invention relates to novel 6-acetylmorphine analogs, and methods for their synthesis and use. Such analogs are designed to provide a convenient linkage chemistry for coupling under mild conditions to a suitable group on a target protein, polypeptide, solid phase or detectable label.
    Type: Grant
    Filed: November 29, 2021
    Date of Patent: April 18, 2023
    Assignee: ALERE SAN DIEGO, INC.
    Inventors: Mariusz Banaszczyk, Normand Hébert, Neil Stowe
  • 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE
    Publication number: 20220080042
    Abstract: The present invention relates to novel 6-acetylmorphine analogs, and methods for their synthesis and use. Such analogs are designed to provide a convenient linkage chemistry for coupling under mild conditions to a suitable group on a target protein, polypeptide, solid phase or detectable label.
    Type: Application
    Filed: November 29, 2021
    Publication date: March 17, 2022
    Inventors: Mariusz BANASZCZYK, Normand HÉBERT, Neil STOWE
  • 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE
    Publication number: 20180353597
    Abstract: The present invention relates to novel 6-acetylmorphine analogs, and methods for their synthesis and use. Such analogs are designed to provide a convenient linkage chemistry for coupling under mild conditions to a suitable group on a target protein, polypeptide, solid phase or detectable label.
    Type: Application
    Filed: August 20, 2018
    Publication date: December 13, 2018
    Applicant: ALERE SAN DIEGO, INC.
    Inventors: Mariusz BANASZCZYK, Normand HÉBERT, Neil STOWE
  • 6-acetylmorphine analogs, and methods for their synthesis and use
    Patent number: 10052379
    Abstract: The present invention relates to novel 6-acetylmorphine analogs, and methods for their synthesis and use. Such analogs are designed to provide a convenient linkage chemistry for coupling under mild conditions to a suitable group on a target protein, polypeptide, solid phase or detectable label.
    Type: Grant
    Filed: July 3, 2017
    Date of Patent: August 21, 2018
    Assignee: ALERE SAN DIEGO, INC.
    Inventors: Mariusz Banaszczyk, Normand Hébert, Neil Stowe
  • 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE
    Publication number: 20170296654
    Abstract: The present invention relates to novel 6-acetylmorphine analogs, and methods for their synthesis and use. Such analogs are designed to provide a convenient linkage chemistry for coupling under mild conditions to a suitable group on a target protein, polypeptide, solid phase or detectable label.
    Type: Application
    Filed: July 3, 2017
    Publication date: October 19, 2017
    Inventors: Mariusz BANASZCZYK, Normand HÉBERT, Neil STOWE
  • 6-acetylmorphine analogs, and methods for their synthesis and use
    Patent number: 9694069
    Abstract: The present invention relates to novel 6-acetylmorphine analogs, and methods for their synthesis and use. Such analogs are designed to provide a convenient linkage chemistry for coupling under mild conditions to a suitable group on a target protein, polypeptide, solid phase or detectable label.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: July 4, 2017
    Assignee: ALERE SAN DIEGO, INC.
    Inventors: Mariusz Banaszczyk, Normand Hébert, Neil Stowe
  • 6-ACETYLMORPHINE ANALOGS, AND METHODS FOR THEIR SYNTHESIS AND USE
    Publication number: 20160022809
    Abstract: The present invention relates to novel 6-acetylmorphine analogs, and methods for their synthesis and use. Such analogs are designed to provide a convenient linkage chemistry for coupling under mild conditions to a suitable group on a target protein, polypeptide, solid phase or detectable label.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Inventors: Mariusz BANASZCZYK, Normand HÉBERT, Neil STOWE
  • Hepatitis C virus polymerase inhibitors
    Publication number: 20080200512
    Abstract: The invention provides a compound of formula: and methods for making and using the same, where R1 and R2 are independently hydrogen, C1-6 alkyl or C1-6 haloalkyl; R3 is hydrogen, halogen, C1-6 alkyl or C1-6 alkoxy; R4 is hydrogen or halogen; and R5 is a mono- or di-amino acid moiety, a succinic acid moiety, a urea moiety, or a derivative thereof. The invention also provides pharmaceutical compositions comprising a compound of formula I, and methods for making and using the same.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 21, 2008
    Inventors: Jeffrey Mark Blaney, Normand Hebert, Stephanie Ann Hopkins, Elizabeth A. Jefferson, Masaki Tomimoto
  • Nr1h4 nuclear receptor binding compounds
    Publication number: 20070010562
    Abstract: The present invention relates to compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of said nuclear receptor by said compounds and the production of medicaments using said compounds.
    Type: Application
    Filed: August 13, 2002
    Publication date: January 11, 2007
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hebert, John Kiely, Ingo Kober, Manfred Kogl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • FXR NR1H4 nuclear receptor binding compounds
    Patent number: 7098336
    Abstract: The invention provides compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
    Type: Grant
    Filed: August 13, 2002
    Date of Patent: August 29, 2006
    Assignee: Phenex Pharmaceuticals AG
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hébert, John Kiely, Ingo Kober, Manfred Kögl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • NR1H4 nuclear receptor binding compounds
    Patent number: 7034046
    Abstract: The present invention relates to compounds according to the general formula (I) which bind to the nuclear receptor, NR1H4, and act as agonists and antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: April 25, 2006
    Assignee: Phenex Pharmaceuticals AG
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hébert, John Kiely, Ingo Kober, Manfred Kögl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • NR1H4 nuclear receptor binding compounds
    Patent number: 6974830
    Abstract: The present invention relates to compounds according to the general formula (I) which bind to the NR1H4 receptor and act as agonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
    Type: Grant
    Filed: July 1, 2002
    Date of Patent: December 13, 2005
    Assignee: Phenix Pharmaceuticals AG
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hébert, John Kiely, Ingo Kober, Manfred Kögl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • Oligomeric aminodiol-containing compounds, libraries thereof, and process of preparing the same
    Patent number: 6828427
    Abstract: Oligomeric compounds comprising a plurality of aminodiol monomer subunits joined by linking groups are provided, as well as libraries of such compounds and processes for preparing the oligomeric compounds and libraries.
    Type: Grant
    Filed: March 25, 1998
    Date of Patent: December 7, 2004
    Assignee: ISIS Pharmaceuticals, Inc.
    Inventor: Normand Hebert
  • Thioquinazolinone derivatives and combinatorial libraries thereof
    Publication number: 20040102629
    Abstract: The present invention relates to novel thioquinazolinone derivative compounds and combinatorial libraries of the following formula: 1
    Type: Application
    Filed: November 26, 2002
    Publication date: May 27, 2004
    Inventors: Zach Cheruvallath, R. Normand Hebert
  • Bicyclic thiophene derivatives and combinatorial libraries thereof
    Publication number: 20030232994
    Abstract: The present invention relates to novel bicyclic thiophene derivative compounds of the following formula: 1
    Type: Application
    Filed: October 4, 2001
    Publication date: December 18, 2003
    Inventors: Shao-Po Lu, Normand Hebert
  • NR1H4 nuclear receptor binding compounds
    Publication number: 20030187042
    Abstract: The present invention relates to compounds according to the general formula (I) which bind to the nuclear receptor, NR1H4, and act as agonists and antagonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds.
    Type: Application
    Filed: July 1, 2002
    Publication date: October 2, 2003
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hebert, John Kiely, Ingo Kober, Manfred Kogl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • 1,2-disubstituted-6-oxo-3-phenyl-piperidine-3-carboxamides and combinatorial libraries thereof
    Publication number: 20030171588
    Abstract: The invention relates to combinatorial libraries containing two or more novel piperidine-3-carboxamide derivative compounds, methods of preparing the piperidine-3-carboxamide derivative compounds and piperidine-3-carboxamide derivative compounds bound to a resin
    Type: Application
    Filed: March 7, 2002
    Publication date: September 11, 2003
    Inventors: Jeffrey D. Kahl, Normand Hebert
  • NR1H4 nuclear receptor binding compounds
    Publication number: 20030149087
    Abstract: The present invention relates to compounds according to the general formula (I) which bind to the NR1H4 receptor and act as agonists of the NR1H4 receptor. The invention further relates to the treatment of diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
    Type: Application
    Filed: July 1, 2002
    Publication date: August 7, 2003
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hebert, John Kiely, Ingo Kober, Manfred Kogl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • FXR NR1H4 nuclear receptor binding compounds
    Publication number: 20030130296
    Abstract: The invention provides compounds according to the general formula (1) which bind to the NR1H4 receptor and act as agonists, antagonists or mixed agonists/antagonists of the NR1H4 receptor. The invention further provides methods of treating diseases and/or conditions through binding of the nuclear receptor by the compounds and the production of medicaments using the compounds.
    Type: Application
    Filed: August 13, 2002
    Publication date: July 10, 2003
    Inventors: Ulrike Bauer, Zach Cheruvallath, Ulrich Deuschle, Elena Dneprovskaia, Tim Gahman, Kristina Giegrich, Ronnie Hanecak, Normand Hebert, John Kiely, Ingo Kober, Manfred Kogl, Harald Kranz, Claus Kremoser, Matthew Lee, Kerstin Otte, Carlton Sage, Manish Sud
  • Chemical reaction apparatus and methods
    Patent number: 6558633
    Abstract: Chemical reaction apparatus, materials and methods are provided for the automatable, efficient synthesis of chemical species and libraries. In accordance with preferred embodiments, chemical droplet generation and direction techniques are employed to prepare oligomers and libraries of chemical species. Reaction assemblies adapted for efficient synthetic employment and for improved collection are also disclosed.
    Type: Grant
    Filed: September 21, 1994
    Date of Patent: May 6, 2003
    Assignee: ISIS Pharmaceuticals, Inc.
    Inventors: David J. Ecker, Oscar Acevedo, Normand Hebert, Peter W. Davis, Jacqueline R. Wyatt, John S. Kiely