Patents by Inventor Normando E. IZNAGA ESCOBAR

Normando E. IZNAGA ESCOBAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF PATIENTS DIAGNOSED WITH PANCREATIC DUCTAL ADENOCARCINOMA USING MONOCLONAL ANTIBODIES AGAINST THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR)
    Publication number: 20250099582
    Abstract: The present invention relates to the field of immunotherapy of cancer, in particular pancreatic ductal adenocarcinoma (PDAC). More specifically, the present invention provides means and methods for treatment of a population of PDAC patients suffering from PDAC tumors which express wild-type KRAS, HRAS or NRAS. The means and methods of the invention envisaged administration of an anti-EGFR antibody or antigen-binding fragment or peptide thereof to the patients. Means and methods for selecting patients and tumors for their responsiveness to the treatment are also provided herein.
    Type: Application
    Filed: September 4, 2024
    Publication date: March 27, 2025
    Applicants: INNOCIMAB PTE LTD, ONCOSCIENCE AG
    Inventors: Rikrik Asiyah ILYAS, Dirk STRUMBERG, Dirk REUTER, Dirk M. BEHRINGER, Ferdinand BACH, Normando E. IZNAGA ESCOBAR
  • TREATMENT OF PATIENTS DIAGNOSED WITH PANCREATIC DUCTAL ADENOCARCINOMA USING USING MONOCLONAL ANTIBODIES AGAINST THE EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR)
    Publication number: 20180221478
    Abstract: The present disclosure relates to the field of immunotherapy of cancer, in particular pancreatic ductal adenocarcinoma (PDAC). Means and methods for treatment of a population of PDAC patients suffering from PDAC tumours which express wildtype KRAS, HRAS or NRAS are disclosed. The claimed antibody is Nimotuzumab. The pancreatic cancer preferably does not contain KRAS mutations at position 12, 16, 61, 154.
    Type: Application
    Filed: July 27, 2016
    Publication date: August 9, 2018
    Applicants: INNOCIMAB PTE LTD, ONCOSCIENCE AG
    Inventors: Dirk STRUMBERG, Beate SCHULTHEIS, Matthias P. EBERT, Jens SIVEKE, Andrea KERKHOFF, Ralf HOFHEINZ, Dirk M. BEHRINGER, Wolfgang E. SCHMIDT, Erdem GOKER, Sara DE DOSSO, Michael KNEBA, Suayib YALCIN, Friedrich OVERKAMP, Frank SCHLEGEL, Markus DOMMACH, Robert ROHRBERG, Tilman STEINMETZ, Ferdinand BACH, Dirk REUTER, Rikrik Asiyah ILYAS, Normando E. IZNAGA ESCOBAR