Abstract: Diagnosing a pathology using LIBS and biological fluids includes focusing light on to a sample on a substrate to cause ablation of the sample and formation of a plasma, collecting optical emission from the plasma, and providing the optical emission to a spectroscopic acquisition component that provides information on spectral data of the plasma. The spectral data is provided to a machine learning algorithm to diagnose a pathology in the sample, where the algorithm is trained on a training set that includes spectral features in a difference spectrum derived from differences between a first LIBS optical emission spectrum collected from one or more samples of the biological fluid that have the pathology or known progress of the pathology and a second LIBS optical emission spectrum collected from one or more samples of the predetermined biological fluid that do not have the pathology or the known progress of the pathology.

Abstract: Systems and methods for diagnosing or monitoring progress of a pathology using laser induced breakdown spectroscopy (LIBS) and machine learning are disclosed.

Abstract: A method of analyzing, preferably by laser induced breakdown spectroscopy (LIBS), fluid samples (e.g. liquids, solutions, melts or slurries) that contain soluble and insoluble components of various elemental, molecular and biological components using a pre-characterized, preferably non-magnetic, membrane or plurality of membranes each having different characteristics, such as different porosities. The fluid sample is first deposited on the one or more membranes and the components to be analyzed are retained thereon through filtration or diffusion and then analyzed, such as with LIBS. Different components, such as different sized particles, are fixed on different membranes depending on the characteristics (e.g. pore size) of the corresponding membrane, which provides pre-sorting of the components before LIBS analysis.

Abstract: Systems and methods for diagnosing or monitoring progress of a pathology using laser induced breakdown spectroscopy (LIBS) and machine learning are disclosed.

Abstract: A method of analyzing, preferably by laser induced breakdown spectroscopy (LIBS), fluid samples (e.g. liquids, solutions, melts or slurries) that contain soluble and insoluble components of various elemental, molecular and biological components using a pre-characterized, preferably non-magnetic, membrane or plurality of membranes each having different characteristics, such as different porosities. The fluid sample is first deposited on the one or more membranes and the components to be analyzed are retained thereon through filtration or diffusion and then analyzed, such as with LIBS. Different components, such as different sized particles, are fixed on different membranes depending on the characteristics (e.g. pore size) of the corresponding membrane, which provides pre-sorting of the components before LIBS analysis.

Abstract: The present invention provides a system and method for determining bilirubin levels in an individual based on skin coloration using a smartphone or other personal device and an attached ancillary apparatus. The device, such as a smartphone or tablet, is capable of storing and running software. The device is also coupled to both a camera and light source to obtain data regarding the skin's coloration. Software is installed on the device to control the light source and calculate bilirubin levels in the individual based on the input received from the camera. The ancillary apparatus is a mechanism surrounding the light source and camera that is placed on the skin of the individual when the system is in use. The ancillary apparatus thus creates a light tight seal between the skin, light source and camera, enabling the system to receive the most accurate data from the camera.

Abstract: An apparatus, method, and computer readable medium for writing data on a highly indestructible material is disclosed. A laser may write data on a first side of a highly indestructible material. The data may then be marked as non-rewriteable. The data may also be written on a second side of the highly indestructible material, with the second side being opposite the first side. The highly indestructible material may comprise a stainless steel storage medium.

Abstract: An apparatus, method, and computer readable medium for writing data on a highly indestructible material is disclosed. A laser may write data on a first side of a highly indestructible material. The data may then be marked as non-rewriteable. The data may also be written on a second side of the highly indestructible material, with the second side being opposite the first side. The highly indestructible material may comprise a stainless steel storage medium.

Abstract: The present invention provides a system and method for determining bilirubin levels in an individual based on skin coloration using a smartphone or other personal device and an attached ancillary apparatus. The device, such as a smartphone or tablet, is capable of storing and running software. The device is also coupled to both a camera and light source to obtain data regarding the skin's coloration. Software is installed on the device to control the light source and calculate bilirubin levels in the individual based on the input received from the camera. The ancillary apparatus is a mechanism surrounding the light source and camera that is placed on the skin of the individual when the system is in use. The ancillary apparatus thus creates a light tight seal between the skin, light source and camera, enabling the system to receive the most accurate data from the camera.

Abstract: An apparatus, method, and computer readable medium for writing data on a highly indestructible material is disclosed. A laser may write data on a first side of a highly indestructible material. The data may then be marked as non-rewriteable. The data may also be written on a second side of the highly indestructible material, with the second side being opposite the first side. The highly indestructible material may comprise a stainless steel storage medium.

Abstract: An apparatus, method, and computer readable medium for writing data on a highly indestructible material is disclosed. A laser may write data on a first side of a highly indestructible material. The data may then be marked as non-rewriteable. The data may also be written on a second side of the highly indestructible material, with the second side being opposite the first side. The highly indestructible material may comprise a stainless steel storage medium.

Abstract: An optical sound detection system including: a laser source to generate a laser beam; an optical fiber; an optical sensor aligned to detect a detected portion of a diffraction pattern formed by the laser light emitted from the output coupling port of the optical fiber; and a signal processor to process the signal produced by the optical sensor. The optical fiber includes: a core that includes a photoelastically active material; an input coupling port optically coupled to the laser source to couple the laser beam into the core of the optical fiber; and an output coupling port from which the laser light is emitted after propagating through the core. The optical sensor is adapted to produce a signal corresponding to the detected portion of the diffraction pattern.

Abstract: Methods for tagging an object with an element-coded particle and identifying the object based on the element code are described. LIBS analysis can be used with the methods to provide a high resolution system for identifying and quantifying objects with great specificity. Objects can include biological and chemical molecules.

Abstract: An optical sound detection system including: a laser source to generate a laser beam; an optical fiber; an optical sensor aligned to detect a detected portion of a diffraction pattern formed by the laser light emitted from the output coupling port of the optical fiber; and a signal processor to process the signal produced by the optical sensor. The optical fiber includes: a core that includes a photoelastically active material; an input coupling port optically coupled to the laser source to couple the laser beam into the core of the optical fiber; and an output coupling port from which the laser light is emitted after propagating through the core. The optical sensor is adapted to produce a signal corresponding to the detected portion of the diffraction pattern.

Abstract: A method for curing polymerizable compositions by irradiating the compositions with a pulsed light that is emitted from an LED. The method of the present invention is especially suitable for curing dental compositions.

Abstract: A method for curing polymerizable compositions by irradiating the compositions with light that is emitted from an LED. The method of the present invention is especially preferred for curing dental compositions.

Abstract: A method for curing polymerizable compositions by irradiating the compositions with light that is emitted from an LED. The method of the present invention is especially preferred for curing dental compositions.

Abstract: A method for curing polymerizable compositions by irradiating the compositions with a pulsed light that is emitted from an LED. The method of the present invention is especially suitable for curing dental compositions.

Abstract: A device for coupling incident radiation to a single mode fiber optic a solid state interferormeter having a front end similar to a Mach-Zehnder integrated interferometer and a back end formed by two converging radiation channels converging at an angle ? and terminating prior to overlapping. The angle ? is calculated to produce an interference zone formed by the exiting radiation a primary constructive interference fringe that provides an optimum match to an input fiber mode of a fiber positioned within the interference zone.

Abstract: A device for simultaneously coupling and modulating incident radiation to a single mode optical fiber based on a solid state truncated integrated Mach-Zehnder interferometer having a back end formed by two converging radiation channels converging at an angle &thgr; and terminating prior to overlapping. The angle &thgr; is calculated to produce in an interference zone formed by the exiting radiation a primary constructive interference fringe that provides an optimum match to an input fiber mode of a fiber positioned within the interference zone. Phase shifting elements in the radiation propagation paths provide a linear shift of the constructive interference fringe across the input of the fiber optic in response to an analog signal.