Abstract: A method produces a pharmaceutical product using a manufacture execution system (MES), and an automation system, such as a batch system. The automation system is configured to drive and to monitor production machines located at a plant floor level. The method is characterized in that it communicatively couples the MES with the automation system, it receives at the MES from the automation system at least one event representative of a situation that has occurred at the plant floor level and relative to the machines, and it depends on the event received at the MES starting at least one workflow controlled by the MES.

Abstract: A method protects at least two redundant servers. The redundant servers act as main and shadow interfaces between respectively at least two redundant process servers coupled to a manufacturing execution system and at least two redundant control servers coupled to an automation part. Each of the servers is configured to receive automation data from each of the redundant control servers. A time of receipt and a tag are extracted from the automation data and are registered in a database coupled with the servers. If one of the tags is registered within a predefined delay after the time of receipt of the other tag, the server with the older time of receipt is set up as the main interface and the other server is set up as the shadow interface.

Abstract: A method protects at least two redundant servers. The redundant servers act as main and shadow interfaces between respectively at least two redundant process servers coupled to a manufacturing execution system and at least two redundant control servers coupled to an automation part. Each of the servers is configured to receive automation data from each of the redundant control servers. A time of receipt and a tag are extracted from the automation data and are registered in a database coupled with the servers. If one of the tags is registered within a predefined delay after the time of receipt of the other tag, the server with the older time of receipt is set up as the main interface and the other server is set up as the shadow interface.

Abstract: A method produces a pharmaceutical product using a manufacture execution system (MES), and an automation system, such as a batch system. The automation system is configured to drive and to monitor production machines located at a plant floor level. The method is characterized in that it communicatively couples the MES with the automation system, it receives at the MES from the automation system at least one event representative of a situation that has occurred at the plant floor level and relative to the machines, and it depends on the event received at the MES starting at least one workflow controlled by the MES.